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Diagnostic Microbiology of the Immunocompromised Host
Over the past twenty-five years, the number of patients with compromised immune systems has grown astronomically. High-risk patients such as these require a unique set of healthcare solutions that take into consideration everything from the etiology and degree of immune suppression to the individual patient’s nutritional status. This comprehensive volume, assembled by a group of distinguished authors, examines a wide range of approaches and challenges to infectious disease diagnostics for immunocompromised patients.
Divided into four sections, the book takes a multifaceted approach to the detection and characterization of infections encountered in this high-risk patient group. The first section provides a broad explanation of the causes of immune suppression, the populations at risk for infections, and the various kinds of infections. The next section addresses crucial laboratory diagnostic methods for individual pathogens, while the third section takes a more systematic perspective on the affected organs in immunocompromised patients. The volume concludes with a discussion of future trends in the field. The material is clearly summarized in practical, user-friendly procedures that can be applied to everyday patient care challenges.
This book will be an indispensable reference for laboratory professionals, infectious disease physicians, oncologists, and other healthcare providers who care for immunocompromised patients.
Hardcover, 479 pages, full-color insert, illustrations, index.
[+] I. HOSTS AND INFECTIONS
[+] II. LABORATORY DIAGNOSIS: SPECIFIC ETIOLOGIC AGENTS
[+] III. LABORATORY DIAGNOSIS: AN ORGAN SYSTEMS APPROACH
[+] IV. FUTURE TRENDS
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18 August 2013
At A Glance
In addition to the usual litany of pathogens that threaten all of us, patients with compromised immune status are susceptible to normally harmless microbial cohabitants. Such infections may become invasive and life-threatening, in recent years affecting growing numbers of patients. This book focuses on the implementation of diagnostic techniques for a special purpose, that of accurately and rapidly diagnosing infections of the immunocompromised patient.
The number of immune suppressed patients has increased tremendously in the last decade. In these patients, the accurate and quick identification of the infecting agent can often be life saving. Thus a book dedicated to this purpose is valuable to microbiologists.
The purpose is to review the classes of infecting microorganisms that cause disease in humans and the diagnostic assays available to detect these agents. This book describes how these infecting pathogens may present in the immune suppressed patient in an unusual manner. This is clearly a unique perspective on diagnosing infections.
This book is written for diagnostic laboratory scientists such as pathologists, medical microbiologists, or infectious disease physicians. The authors are all practicing diagnostic physicians or scientists with many years of experience in laboratory medicine.
The first chapter stands alone and provides an introduction to the immune suppressed patient. The authors present information on the normal immune response and then on the numerous ways in which patients can become immunocompromised. The book is then divided into two major sections, the first of which reviews the infectious pathogens. It covers each of the various microorganisms such as fungal agents, parasites, and viral agents, as well as mycobacterial and bacterial organisms. This section is followed by chapters on organ-specific infections. These chapters detail all the pathogens that cause infections in specific locations in the body such as the respiratory tract or the gastrointestinal tract. The final chapter provides an enlightening perspective on the future prospects of diagnostic tests and how testing for infectious agents will rapidly change with this new technology.
This is a valuable resource for laboratories involved in diagnosing infectious processes in the immune suppressed patient population. The one recommendation I have for the next edition is to use additional pictures, especially in the first section on the description of pathogens. This would be helpful for confirming a diagnosis. I anticipate this is a reference source that will be used often to determine various options to detect infections in this patient population.
Reviewer: Rebecca Horvat, PhD, D(ABMM) (University of Kansas Medical Center)
Review Date: Unknown
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