Chapter 10 : Filamentous Fungi

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This chapter discusses the most common causes of invasive mold infections, and provides a brief mention of particular molds that are less frequent causes of infection. The hyaline septate molds are covered first, with emphasis on species, species, and . A section talks about two dimorphic fungal pathogens, and , and also about less commonly encountered hyaline septate molds. Next, it discusses the , and and species are included because they are the genera most frequently encountered. Clinical Laboratory Standards Institute (CLSI) document 38-A addresses the standard broth dilution methods for determining antifungal resistance in the filamentous fungi . Alternatively, some authors have shown the utility of other methods, such as the Etest, for determining antifungal resistance in the filamentous fungi. The presence of a single colony of a mold in a respiratory specimen may simply represent the presence of transient fungal flora or a plate contaminant; however, it could also be evidence of an invasive fungal infection in an immunocompromised host. Every mycology laboratory should be able to definitively identify certain filamentous fungi. Microscopic examination reveals the spore morphology, the conidiophore, and the method of conidiogenesis. These features, when studied with identification keys and atlases, should afford the identification of the most commonly encountered filamentous fungi.

Citation: Procop G, Hayden R, Roberts G. 2009. Filamentous Fungi, p 195-219. In Hayden R, Carroll K, Tang Y, Wolk D (ed), Diagnostic Microbiology of the Immunocompromised Host. ASM Press, Washington, DC. doi: 10.1128/9781555815455.ch10

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Fungal Infections
Antifungal Agents
Tumor Necrosis Factor alpha
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Table 1.

Filamentous fungi that medical mycology laboratories should be able to identify

Citation: Procop G, Hayden R, Roberts G. 2009. Filamentous Fungi, p 195-219. In Hayden R, Carroll K, Tang Y, Wolk D (ed), Diagnostic Microbiology of the Immunocompromised Host. ASM Press, Washington, DC. doi: 10.1128/9781555815455.ch10
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Table 2.

Strengths and limitations of selected antifungal agents

Citation: Procop G, Hayden R, Roberts G. 2009. Filamentous Fungi, p 195-219. In Hayden R, Carroll K, Tang Y, Wolk D (ed), Diagnostic Microbiology of the Immunocompromised Host. ASM Press, Washington, DC. doi: 10.1128/9781555815455.ch10

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