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is an obligate intracellular protozoan that has the ability to infect all mammals, as well as birds and rodents, who serve as intermediate hosts. In immunocompetent hosts, 90% of primary infections caused by are asymptomatic. Reactivation of can thus lead to long-term consequences of a primary infection that occurred in the remote past. has a complex life cycle, with both asexual and sexual reproduction leading to the formation of three different forms of the protozoan. Congenital toxoplasmosis results from the transplacental transmission of infective tachyzoites from a mother with a primary toxoplasmosis infection. Ocular toxoplasmosis can occur in both immunocompetent and immunocompromised hosts and can lead to wide array of symptoms, from asymptomatic retinal scars to blindness requiring enucleation. Clinically, ocular toxoplasmosis can cause a range of symptoms. In Tanzania, a study of 849 pregnant women revealed evidence of congenital toxoplasma infection in 0.8% of newborns. Thus, though congenital toxoplasmosis in the United States is uncommon, its frequency in other countries makes it a worldwide newborn health problem. Most cases of toxoplasma encephalitis occur in human immunodeficiency virus (HIV)-infected individuals with AIDS. Other risk factors associated with toxoplasma encephalitis include lymphoma (either Hodgkin’s or non-Hodgkin’s lymphoma), treatment with immunosuppressants for other malignancies or following organ transplantation, and use of high-dose steroids.

Citation: Kravetz J. 2009. , p 217-228. In Fratamico P, Smith J, Brogden K (ed), Sequelae and Long-Term Consequences of Infectious Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555815486.ch12

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Figure 1.

Risk of congenital infection according to duration of gestation at maternal seroconversion. (Reprinted from [ ] with permission from Elsevier.)

Citation: Kravetz J. 2009. , p 217-228. In Fratamico P, Smith J, Brogden K (ed), Sequelae and Long-Term Consequences of Infectious Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555815486.ch12
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Figure 2.

Risk of developing clinical signs (not necessarily symptomatic) before age 3 years according to gestational age. (Reprinted from [ ] with permission from Elsevier.)

Citation: Kravetz J. 2009. , p 217-228. In Fratamico P, Smith J, Brogden K (ed), Sequelae and Long-Term Consequences of Infectious Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555815486.ch12
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Figure 3.

Seroprevalence of , by age and sex; Third National Health and Nutrition Examination Survey, 1988–1994. White bars represent males, black bars represent females. In the age group 30 to 39 years (*), seroprevalence was higher in males than in females ( = 0.02). Among children under 12 years (†), seroprevalence estimates are unstable because of low sample representation in these categories. (Reprinted from the [ ] with permission of Oxford University Press.)

Citation: Kravetz J. 2009. , p 217-228. In Fratamico P, Smith J, Brogden K (ed), Sequelae and Long-Term Consequences of Infectious Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555815486.ch12
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Figure 4.

T1-weighted axial gadolinium-enhanced magnetic resonance image of toxoplasmosis encephalitis. (Image reprinted with permission from eMedicine.com, 2008; available at http://emedicine.medscape.com/article/344706-overview.)

Citation: Kravetz J. 2009. , p 217-228. In Fratamico P, Smith J, Brogden K (ed), Sequelae and Long-Term Consequences of Infectious Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555815486.ch12
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1. Abtrall, S.,, C. Rabaud, and, D. Costagliola. 2001. Incidence and risk factors for toxoplasmic encephalitis in human immunodeficiency virus-infected patients before and during the highly active antiretroviral therapy era. Clin. Infect. Dis. 33:17471755.
2. Antinori, A.,, D. Larussa,, A. Cingolani,, P. Lorenzini,, S. Bossolasco,, M. G. Finazzi,, M. Bongiovanni,, G. Guaraldi,, S. Grisetti,, B. Vigo,, B. Gigli,, A. Mariano,, E. R. Dalle Nogare,, M. De Marco,, F. Moretti,, P. Corsi,, N. Abrescia,, P. Rellecati,, A. Castragna,, C. Mussini,, A. Ammassari,, P. Cinque,, A. D’Arminio Monforte, and Italian Registry Investigaive NeuroAIDS. 2004. Prevalence, associated factors, and prognostic determinants of AIDS-related toxoplasmic encephalitis in the era of advanced highly active antiretroviral therapy. Clin. Infect. Dis. 39:16811691.
3. Baril, L.,, T. Ancelle,, V. Goulet,, P. Thulliez,, V. Tirard-Fleury, and, B. Carme. 1999. Risk factors for Toxoplasma infection in pregnancy: a case-control study in France. Scand. J. Infect. Dis. 31:305309.
4. Belanger, F.,, F. Derouin,, L. Grangeot-Keros, and, L. Meyer. 1999. Incidence and risk factors of toxoplasmosis in a cohort of human immunodeficiency virus-infected patients: 1988–1995. Clin. Infect. Dis. 28:575581.
5. Benson, C. A.,, J. E. Kaplan,, H. Masur,, A. Pau, and, K. K. Holmes. 2004. Treating opportunistic infections among HIV-infected adults and adolescents. Recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association/Infectious Diseases Society of America. MMWR Morb. Mortal. Wkly. Rep. 53:1112.
6. Bertschy, S.,, M. Opravil,, M. Cavassini,, E. Bernasconi,, V. Schiffer,, P. Schmid,, M. Flepp,, J.-P. Chave,, A. Christen, and, H. Furrer. 2006. Discontinuation of maintenance therapy against toxoplasma encephalitis in AIDS patients with sustained response to antiretroviral therapy. Clin. Microbiol. Infect. 12:666671.
7. Bobic, B.,, I. Jevremovic,, J. Marinkovic,, D. Sibalic, and, O. Djurkovic-Djakovic. 1998. Risk factors for Toxoplasma infection in a reproductive age female population in the area of Belgrade, Yugoslavia. Eur. J. Epidemiol. 14:605610.
8. Bosch-Driessen, L. H.,, S. Karimi,, J. S. Stilma, and, A. Rothova. 2000. Retinal detachment in ocular toxoplasmosis. Ophthalmology 107:3640.
9. Brown, A. S.,, C. A. Schaefer,, C. P. Quesenberry,, L. Liu,, V. P. Babulas, and, E. S. Susser. 2005. Maternal exposure to toxoplasmosis and risk of schizophrenia in adult offspring. Am. J. Psychiatry 162:767773.
10. Centers for Disease Control and Prevention. 2000. CDC recommendations regarding selected conditions affecting women’s health. MMWR Morb. Mortal. Wkly. Rep. 49:5968.
11. Cetinkaya, Z.,, S. Yazar,, O. Gecici, and, M. N. Namli. 2007. Anti-Toxoplasma gondii antibodies in patients with schizophrenia—preliminary findings in a Turkish sample. Schizophren. Bull. 33:789791.
12. Chandenier, J.,, G. Jarry,, D. Nassif,, Y. Couadi,, L. Paris,, P. Thulliez,, E. Bourges-Petit, and, C. Raccurt. 2000. Congestive heart failure and myocarditis after seroconversion for toxoplasmosis in two immunocompetent patients. Eur. J. Clin. Microbiol. Infect. Dis. 19:375379.
13. Cook, A. J.,, R. E. Gilbert,, W. Buffolano,, J. Zufferey,, E. Petersen,, P. A. Jenum,, W. Foulon,, A. E. Semprini, and, D. T. Dunn. 2000. Sources of toxoplasma infection in pregnant women: European multicentre case-control study. Br. Med. J. 321:142147.
14. Cuturic, M.,, G. R. Hayat,, C. A. Vogler, and, A. Velasques. 1997. Toxoplasmic polymyositis revisited: case report and review of literature. Neuromuscul. Disord. 7:390396.
15. da Silva, D. S.,, L. M. Bahia-Oliveira,, S. K. Shen,, O. C. Kwok,, T. Lehman, and, J. P. Dubey. 2003. Prevalence of Toxoplasma gondii in chickens from an area in southern Brazil highly endemic to humans. J. Parasitol. 89:394396.
16. Dedicoat, M.,, and N. Livesley. 2006. Management of toxoplasmic encephalitis in HIV-infected adults (with an emphasis on resource-poor settings). Cochrane Database Syst. Rev. 3:CD005420.
17. DeSalvador-Guillouet, F.,, D. Ajzenberg,, S. Chaillou-Opitz,, M. Saint-Paul,, B. Dunais,, P. Dellamonica, and, P. Marty. 2006. Severe pneumonia during primary infection with an atypical strain of Toxoplasma gondii in an immunocompetent young man. J. Infect. 53:e47e50.
18. Despommier, D. D.,, R. W. Gwadz, and, P. J. Hotez. 1995. Toxoplasma gondii, p. 162–169. In D. D. Despommier,, R. W. Gwadz, and, P. J. Hotez (ed.), Parasitic Diseases, 3rd ed. Springer-Verlag, New York, NY.
19. Dias, R. A. F.,, I. T. Navarro,, B. B. Ruffolo,, F. M. Bugni,, M. V. Castro, and, R. L. Freire. 2005. Toxoplasma gondii in fresh pork sausage and seroprevalence in butchers from factories in Londrina, Parana State, Brazil. Rev. Inst. Med. Trop. Sao Paulo. 47:185189.
20. Dodds, E. M. 2006. Toxoplasmosis. Curr. Opin. Ophthalmol. 17:557561.
21. Doehring, E.,, I. Reiter-Owona,, O. Bauer,, M. Kaisi,, H. Hlobil,, G. Quade,, N. A. S. Hamudu, and, H. M. Seitz. 1995. Toxoplasma gondii antibodies in pregnant women and their newborns in Dar Es Salaam, Tanzania. Am. J. Trop. Med. Hyg. 52:546548.
22. Dubey, J. P. 1996. Strategies to reduce transmission of Toxoplasma gondii to animals and humans. Vet. Parasitol. 64:6570.
23. Dubey, J. P. 1998. Toxoplasma gondii oocyst survival under defined temperatures. J. Parasitol. 84:862865.
24. Dubey, J. P.,, H. R. Gamble,, D. Hill,, C. Sreekumar,, S. Romand, and, P. Thuilliez. 2002. High prevalence of viable Toxoplasma gondii infection in market weight pigs from a farm in Massachusetts. J. Parasitol. 88:12341238.
25. Dubey, J. P.,, D. H. Graham,, E. Dahl,, C. Sreekumar,, T. Lehmann,, M. F. Davis, and, T. Y. Morishita. 2003. Toxoplasma gondii isolates from free-ranging chickens from the United States. J. Parasitol. 89:10601062.
26. Dubey, J. P.,, D. E. Hill,, J. L. Jones,, A. W. Hightower,, E. Kirkland,, J. M. Roberts,, P. L. Marcet,, T. Lehmann,, M. C. Vianna,, K. Miska,, C. Sreekumar,, O. C. Kwok,, S. K. Shen, and, H. R. Gamble. 2005. Prevalence of viable Toxoplasma gondii in beef, chicken, and pork from retail meat stores in the Unites States: risk assessment to consumers. J. Parasitol. 91:10821093.
27. Dunn, D.,, M. Wallon,, F. Peyron,, E. Petersen,, C. Peckham and, R. Gilbert. 1999. Mother-to-child transmission of toxoplasmosis: risk estimates for clinical counseling. Lancet 353:18291833.
28. Eckert, G. U.,, J. Melamed, and, B. Menegaz. 2007. Optic nerve changes in ocular toxoplasmosis. Eye 21:746751.
29. Freeman, K.,, L. Oakley,, A. Pollak,, W. Buffolano,, E. Petersen,, A. E. Semprini,, A. Salt, and, R. Gilbert. 2005. Association between congenital toxoplasmosis and preterm birth, low birthweight and small for gestational age birth. BJOG 112:3137.
30. Freeman, K.,, A. Salt,, A. Prusa,, G. Malm,, N. Ferret,, W. Buffolano,, D. Schmidt,, H. K. Tan, and, R. E. Gilbert. 2005. Association between congenital toxoplasmosis and parent-reported developmental outcomes, concerns, and impairments, in 3 year old children. BMC Pediatr. 5:2333.
31. Gilber, R.,, H. K. Tan,, S. Cliffe,, E. Guy, and, M. Stanford. 2006. Symptomatic toxoplasma infection due to congenital and postnatally acquired infection. Arch. Dis. Child. 91:495498.
32. Gilbert, R. E.,, and M. R. Stanford. 2000. Is ocular toxoplasmosis caused by prenatal or postnatal infection? Br. J. Ophthalmol. 84:224226.
33. Gras, L.,, R. E. Gilbert,, M. Wallon,, F. Peyron, and, M. Cortina-Borja. 2004. Duration of the IgM response in women acquiring Toxoplasma gondii during pregnancy: implications for clinical practice and cross-sectional incidence studies. Epidemiol. Infect. 132:541548.
34. Guerina, N. G.,, H-W. Hsu,, H. C. Meissner,, J. H. Maguire,, R. Lynfield,, B. Stechenberg,, I. Abroms,, M. S. Pasternack,, R. Hoff,, R. B. Eaton, and, G. F. Grady. 1994. Neonatal serologic screening and early treatment for congenital Toxoplasma gondii infection. N. Engl. J. Med. 330:18581863.
35. Havelaar, A. H.,, J. M. Kemmeren, and, L. M. Kortbeek. 2007. Disease burden of congenital toxoplasmosis. Clin. Infect. Dis. 44:14671474.
36. Holland, G. N. 2003. Ocular toxoplasmosis: a global reassessment. Part 1: epidemiology and course of disease. Am. J. Ophthalmol. 136:973988.
37. Holland, G. N. 2004. Ocular toxoplasmosis: a global reassessment. Part II: Disease manifestations and management. Am. J. Ophthalmol. 137:117.
38. Jara, M.,, H. W. Hsu,, R. B. Eaton, and, A. Demaria, Jr. 2001. Epidemiology of congenital toxoplasmosis identified by population-based newborn screening in Massachusetts. Pediatr. Infect. Dis. J. 20:11321135.
39. Jones, J. L.,, V. J. Dietz,, M. Power,, A. Lopez,, M. Wilson,, T. R. Navin,, R. Gibbs, and, J. Schulkin. 2001. Survey of obstetrician-gynecologists in the United States about toxoplasmosis. Infect. Dis. Obstet. Gynecol. 9:2331.
40. Jones, J. L.,, D. Kruszon-Moran,, M. Wilson,, G. McQuillan,, T. Navin, and, J. B. McAuley. 2001. Toxoplasma gondii infection in the United States: seroprevalence and risk factors. Am. J. Epidemiol. 154:357365.
41. Jones, J. L.,, F. Ogunmodede,, J. Scheftel,, E. Kirkland,, A. Lopez,, J. Schulkin, and, R. Lynfield. 2003. Toxoplasmosis-related knowledge and practices among pregnant women in the United States. Infect. Dis. Obstet. Gynecol. 11:139145.
42. Jumaian, N. F. 2005. Seroprevalence and risk factors for Toxoplasma infection in pregnant women in Jordan. East. Mediterr. Health J. 11:4555.
43. Kapperud, G.,, P. A. Jenum,, B. Stray-Pedersen,, K. K. Melby,, A. Eskild, and, J. Eng. 1996. Risk factors for Toxoplasma gondii infection in pregnancy. Results of a prospective case-control study in Norway. Am. J. Epidemiol. 144:405412.
44. Kaushik, R. M.,, S. K. Mahajan,, A. Sharma,, R. Kaushik, and, R. Kukreti. 2005. Toxoplasmic meningoencephalitis in an immunocompetent host. Trans. R. Soc. Trop. Med. Hyg. 99:874878.
45. Kotton, C. N. 2007. Zoonoses in solid-organ and hematopoietic stem cell transplant recipients. Clin. Infect. Dis. 44:857866.
46. Kravetz, J. D.,, and D. G. Federman. 2005. Prevention of toxoplasmosis in pregnancy: knowledge of risk factors. Infect. Dis. Obstet. Gynecol. 13:161165.
47. Kravetz, J. D.,, and D. G. Federman. 2005. Toxoplasmosis in pregnancy. Am. J. Med. 118:212216.
48. Lebech, M.,, D. H. M. Joynson,, H. M. Seitz,, P. Thulliez,, R. E. Gilbert,, G. N. Dutton,, B. Ovlisen, and, E. Petersen. 1996. Classification system and case definitions of Toxoplasma gondii infection in immunocompetent pregnant women and their congenitally infected offspring. Eur. J. Clin. Microbiol. Infect. Dis. 15:799805.
49. Liesenfeld, O. 2004. Toxoplasmosis. In L. Goldman and, D. Ausiello (ed.), Cecil Textbook of Medicine, 22nd ed. Saunders, Philadelphia, PA.
50. Lindsay, D. S.,, M. V. Collins,, D. Holliman,, G. J. Flick, and, J. P. Dubey. 2006. Effects of high-pressure processing on Toxoplasma gondii tissue cysts in ground pork. J. Parasitol. 92:195196.
51. Maetz, H. M.,, R. N. Kleinstein,, D. Federico, and, J. Wayne. 1987. Estimated prevalence of ocular toxoplasmosis and toxocariasis in Alabama. J. Infect. Dis. 156:414.
52. Mariani, M.,, M. Pagani,, C. Inserra, and, S. DeServi. 2006. Complete atrioventricular block associated with toxoplasma myocarditis. Europace 8:221223.
53. Markell, E. K.,, D. T. John, and, W. A. Krotoski. 1999. Toxoplasma gondii, p. 161–171. In K. Edwards,, D. T. John, and, W. A. Krotoski (ed.), Markell and Voge’s Medical Parasitology, 8th ed. Saunders, Philadelphia, PA.
54. McQuillan, G.,, D. Kruszon-Moran,, B. J. Kottiri,, L. R. Curtin,, J. W. Lucas, and, R. S. Kington. 2004. Racial and ethnic differences in the seroprevalence of 6 infectious diseases in the United States: date from NHANES III, 1988-1994. Am. J. Public Health 94:19521958.
55. Miro, J. M.,, J. C. Lopez,, D. Podzamczer,, J. M. Peña,, J. C. Alberdi,, E. Martínez,, P. Domingo,, J. Cosin,, X. Claramonte,, J. R. Arribas,, M. Santín, and, E. Ribera. 2006. Discontinuation of primary and secondary Toxoplasma gondii prophylaxis is safe in HIV-infected patients after immunological restoration with highly active antiretroviral therapy: results of an open, randomized, multicenter clinical trial. Clin. Infect. Dis. 43:7989.
56. Mombro, M.,, C. Perathoner,, A. Leone,, V. Buttafuoco,, C. Zotti,, M. A. Lievre,, C. Fabris. 2003. Congenital toxoplasmosis: assessment of risk to newborns in confirmed and uncertain maternal infection. Eur. J. Pediatr. 162:703706.
57. Montoya, J. G.,, R. Jordan,, S. Lingamneni,, G. J. Berry, and, J. S. Remington. 1997. Toxoplasmic myocarditis and polymyositis in patients with acute acquired toxoplasmosis diagnosed during life. Clin. Infect. Dis. 24:676683.
58. Montoya, J. G.,, and O. Liesenfeld. 2004. Toxoplasmosis. Lancet 363:19651976.
59. Montoya, J. G.,, and J. S. Remington. 1996. Toxoplasmic chorioretinitis in the setting of acute acquired toxoplasmosis. Clin. Infect. Dis. 23:277282.
60. Mussini, C.,, P. Pezzotti,, A. Govoni,, V. Borghi,, A. Antinori,, A. Monforte,, A. De Luca,, N. Mongiardo,, M. C. Cerri,, F. Chiodo,, E. Concia,, L. Bonazzi,, M. Moroni,, L. Ortona,, R. Esposito,, A. Cossarizza, and, B. De Rienzo. 2000. Discontinuation of primary prophylaxis for Pneumocystis carinii pneumonia and toxoplasmic encephalitis in human immunodeficiency virus type 1-infected patients: the changes in opportunistic prophylaxis study. J. Infect. Dis. 181:16351642.
61. Nascimento, L. V.,, F. Stollar,, L. B. Tavares,, C. E. Cavasini,, I. L. Maia, and, J. A. Cordeiro. 2001. Risk factors for toxoplasmic encephalitis in HIV-infected patients: a case-control study in Brazil. Ann. Trop. Med. Parasitol. 95:587593.
62. Nash, J. Q.,, S. Chissel,, J. Jones,, F. Warburton, and, N. Q. Verlander. 2005. Risk factors for toxoplasmosis in pregnant women in Kent, United Kingdom. Epidemiol. Infect. 133:475483.
63. Nelson, J. C.,, D. J. Kauffmann,, D. Ciavarella, and, W. J. Senisi. 1989. Acquired toxoplasmic retinochoroiditis after platelet transfusions. Ann. Ophthalmol. 21:253254.
64. Neto, E. C.,, E. Anele,, R. Rubim,, A. Brites,, J. Schulte,, D. Becker, and, T. Tuuminen. 2000. High prevalence of congenital toxoplasmosis in Brazil estimated in a 3-year prospective neonatal screening study. Int. J. Epidemiol. 29:941947.
65. Neto, E. C.,, R. Rubin,, J. Schulte, and, R. Giugliani. 2004. Newborn screening for congenital infectious diseases. Emerg. Infect. Dis. 10:10691073.
66. Perkins, E. S. 1973. Ocular toxoplasmosis. Br. J. Ophthalmol. 57:117.
67. Petersen, E. 2007. Toxoplasmosis. Semin. Fetal Neonatal Med. 12:214223.
68. Pradhan, S.,, R. Yadav, and, V. N. Mishra. 2007. Toxoplasma meningoencephalitis in HIV-seronegative patients: clinical patterns, imaging features and treatment outcome. Trans. R. Soc. Trop. Med. Hyg. 101:2533.
69. Reiter-Owona, I.,, R. Bialek,, J. K. Rockstroh, and, H. M. Seitz. 1998. The probability of acquiring primary Toxoplasma infection in HIV-infected patients: results of an 8-year retrospective study. Infection 26:2025.
70. Renold, C.,, A. Sugar,, J.-P. Chave,, L. Perrin,, J. Delavelle,, G. Pizzolato,, P. Burkhard,, V. Gabriel, and, B. Hirschel. 1992. Toxoplasma encephalitis in patients with the Acquired Immunodeficiency Syndrome. Medicine 71:224239.
71. Rorman, E.,, C. S. Zamir,, I. Rilkis, and, H. Ben-David. 2006. Congenital toxoplasmosis—prenatal aspects of Toxoplasma gondii infection. Reprod. Toxicol. 21:458472.
72. Roth, J. A.,, S. E. Siegel,, A. S. Levine, and, C. W. Berard. 1971. Fatal recurrent toxoplasmosis in a patient initially infected via a leukocyte transfusion. Am. J. Clin. Pathol. 56:601605.
73. Schmidt, D. R.,, B. Hogh,, O. Andersen,, J. Fuchs,, H. Fledelius, and, E. Petersen. 2006. The national neonatal screening programme for congenital toxoplasmosis in Denmark: results from the initial four years, 1999–2002. Arch. Dis. Child. 91:661665.
74. Siegel, S. E.,, M. N. Lunde,, A. H. Gelderman,, R. H. Halterman,, J. A. Brown,, A. S. Levine, and, R. G. Graw. 1971. Transmission of toxoplasmosis by leukocyte transfusion. Blood 37:388394.
75. Signorell, L. M.,, D. Seitz,, S. Merkel,, R. Berger, and, C. Rudin. 2006. Cord blood screening for congenital toxoplasmosis in northwestern Switzerland, 1982–1999. Pediatr. Infect. Dis. J. 25:123128.
76. Sijpkens, Y. W.,, R. J. de Knegt, and, S. D. van der Werf. 1994. Unusual presentation of acquired toxoplasmosis in an immunocompetent adult. Neth. J. Med. 45:174176.
77. Smith, R. E.,, and J. P. Ganley. 1972. Ophthalmic survey of a community. 1: abnormalities of the ocular fundus. Am. J. Ophthalmol. 74:11261130.
78. Song, K. J.,, J. C Shin,, H. J. Shin, and, H. W. Nam. 2005. Seroprevalence of toxoplasmosis in Korean pregnant women. Korean J. Parasitol. 2005:6971.
79. Torrey, E. F.,, J. J. Bartko,, Z.-R. Lun, and, R. H. Yolken. 2007. Antibodies to Toxoplasma gondii in patients with schizophrenia: a meta-analysis. Schizophren. Bull. 33:729736.
80. Wallon, M.,, L. Kodjikian,, C. Binquet,, J. Garweg,, J. Fleury,, C. Quantin, and, F. Peyron. 2004. Long-term ocular prognosis in 327 children with congenital toxoplasmosis. Pediatrics 113:15671572.
81. Westfall, A. C.,, A. K. Lauer,, E. B. Suhler, and, J. T. Rosenbaum. 2005. Toxoplasmosis retinochoroiditis and elevated intraocular pressure. A retrospective study. J. Glaucoma 14:310.
82. Yazar, S.,, F. Arman,, S. Yalçin,, F. Demirtaş,, O. Yaman, and, I. şahin. 2003. Investigation of probable relationship between Toxoplasma gondii and cryptogenic epilepsy. Seizure 12:107109.


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Table 1.

Counseling for reduction of primary toxoplasmosis in women of childbearing age

Citation: Kravetz J. 2009. , p 217-228. In Fratamico P, Smith J, Brogden K (ed), Sequelae and Long-Term Consequences of Infectious Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555815486.ch12

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