Full text loading...
Chapter 22 : Complications of Superficial Mycoses
Category: Clinical Microbiology
Ebook: Choose a downloadable PDF or ePub file. Chapter is a downloadable PDF file. File must be downloaded within 48 hours of purchase
Superficial fungal infections are common infections limited to the skin, mucous membranes, hair, and nails. Tinea pedis, usually interdigital type, and toenail onychomycosis are significant risk factors for bacterial cellulitis of the lower legs. It was also demonstrated that thorough examination of the patient’s feet and interdigital spaces will often reveal active tinea pedis. Treatment of this condition could significantly reduce the number of cellulitis episodes. Recently, it was reported that dermatophytoses could be complicated by preseptal cellulitis. Empiric therapy with oral antibacterial and antiviral medications failed to resolve the disease. Candida species and Malassezia species are the most important pathogens in the induction of fungal allergy and may be responsible for allergic rhinitis, allergic sinusitis, atopic asthma, urticaria, or allergic eczema. The importance of hypersensitivity to fungal allergens was underscored in patients suffering from atopic dermatitis, in whom fungal allergens could provoke severe exacerbations. Superficial fungal infections were also described to induce allergic diseases de novo. Remarkably, dermatophytes have also occasionally been reported to be responsible for widespread and invasive infections in immunosuppressed patients. Several studies demonstrated that chronic dermatomycoses, mainly onychomycosis, significantly reduced patients’ quality of life. The majority of patients believed that the nail condition would last for the rest of their lives and claimed that other people found it unpleasant to look at their nails.