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Bacterial Pathogenomics

Editors: Mark J. Pallen1, Karen E. Nelson2, Gail M. Preston3
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Affiliations: 1: University of Birmingham Birmingham, United Kingdom; 2: Department of Biology Howard University Washington, DC and The Institute for Genomic Research Rockville, Maryland; 3: Oxford University Oxford, United Kingdom
Content Type: Monograph
Publication Year: 2007

Category: Genomics and Bioinformatics; Bacterial Pathogenesis

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This landmark volume details progress in the fast-changing world of bacterial genomics. The availability of genome sequences pervades every aspect of bacteriology. Bacteriologists now can examine the genomic sequence for every significant bacterial pathogen of humans, plants, and animals. With chapters from more than forty scientists from around the world, explains the scientific advances that have resulted from the application of bacterial genome sequencing to the study of how bacterial pathogens have evolved and how these bacteria cause disease.

The first half of the book reviews the impact of genomics on our understanding of selected groups of pathogens, including , mycobacteria, , staphylococci, spirochetes, , plant pathogens, and . The remaining chapters cover themes that cut across taxonomic boundaries, such as genomic signatures of intracellularity, the impact of shared genomic tools and datasets, pathogenomics of bacterial biothreat agents, the impact of phages on the evolution of bacterial pathogenicity, gram-positive protein secretion, cell wall biosynthesis, and intracellular pathogens. will prove indispensable in the library of any bacteriology research group and will act as a key text for anyone studying bacterial genomics or the molecular basis of bacterial infection.

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