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Molecular Principles of Fungal Pathogenesis

Editors: Joseph Heitman1, Scott G. Filler2, John E. Edwards, Jr.3, Aaron P. Mitchell4
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Affiliations: 1: Duke University Medical School Durham, North Carolina; 2: Harbor-UCLA Medical Center Torrance, California; 3: Harbor-UCLA Medical Center Torrance, California; 4: Columbia University College of Physicians & Surgeons New York, New York
Content Type: Monograph
Format: Paperback, Electronic
Publication Year: 2006

Category: Fungi and Fungal Pathogenesis

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Molecular Approaches of Fungal Pathogenesis presents readers with an up-to-date compendium of research in the field of medical mycology. This new volume measures the impact of genome projects, genetics, and molecular biology on the understanding of a diverse group of pathogenic fungi and explores the potential impact of vaccines and new therapeutic approaches to treatment. It will serve as a valuable resource for students, fellows, instructors, researchers, specialists, clinicians, and anyone interested in the general field of microbial pathogenesis.

Divided into five sections, the book provides readers with a broad overview of pathogenic fungi, including ascomycetes, basidiomycetes, zygomycetes, and both rare and common infections. A cluster of chapters focuses on immunological aspects of infection involving innate, humoral, and cell-mediated immunity. The remaining chapters of Molecular Principles of Fungal Pathogenesis feature comprehensive coverage of everything from general principles to specific pathogens and vaccine development. An in-depth analysis of the host-pathogen relationship is offered, and future directions are contemplated.

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Doody Enterprises

23 June 2013

At A Glance

Molecular Approaches of Fungal Pathogenesis presents readers with an up-to-date compendium of research in the field of medical mycology. This new volume measures the impact of genome projects, genetics, and molecular biology on the understanding of a diverse group of pathogenic fungi and explores the potential impact of vaccines and new therapeutic approaches to treatment. It will serve as a valuable resource for students, fellows, instructors, researchers, specialists, clinicians, and anyone interested in the general field of microbial pathogenesis. Divided into five sections, the book provides readers with a broad overview of pathogenic fungi, including ascomycetes, basidiomycetes, zygomycetes, and both rare and common infections. A cluster of chapters focuses on immunological aspects of infection involving innate, humoral, and cell-mediated immunity. The remaining chapters of Molecular Principles of Fungal Pathogenesis feature comprehensive coverage of everything from general principles to specific

pathogens and vaccine development. An in-depth analysis of the host-pathogen relationship is offered, and future directions are contemplated.

Description

This book focuses specifically on the molecular basis of fungal pathogenesis, bringing together the current research in pathogenic fungi and presenting it in an organized, systematic fashion.

Purpose

According to the editors, this book is intended to provide "state-of-the-art molecular and genetic approaches" to the classic study of fungal pathogens. The generation of this book is a result of the many years of experience from the molecular mycology course taught at the Marine Biological Laboratories in Woods Hole, Massachusetts. It is intended to set the stage for the next generation of "teaching, research and discovery."

Audience

The book is directed at individuals with research interests in fungal pathogenesis. It brings together the accomplishments that have occurred in this field over the past several years.

Features

The first of the book's five sections is on general principles and covers such topics as the mechanism of antifungal agents and the complicated topic of fungal mating. The next section details model systems used to study fungi such as the use of Drosophila to study Aspergillus and Galleria mellonella used to study Candida species. The third section discusses specific human pathogens such as Cryptococcus species and the soil fungi, Histoplasma capsulatum. The next section examines the host immune response to specific pathogens. In the final section there is discussion of future areas of research and discovery.

Assessment

This is unique. I know of no other reference that details the current information and research on fungal pathogens like this book does. I would highly recommend this book for a graduate level fungal pathogenesis course.

Doody Enterprises

Reviewer: Rebecca Horvat, PhD, D(ABMM) (University of Kansas Medical Center)

Review Date: Unknown

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