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Chapter 104 : Introduction

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Introduction, Page 1 of 2

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Abstract:

This is the introductory chapter to the section . This section covers the important topics of the allergen, in vivo and in vitro confirmatory IgE antibody testing, mediators and markers of allergic inflammation, and application of the analytical measurements to food allergy and hypereosinophilic syndromes. This chapter presents brief insights into each chapter discussed in the section. Chapter 105, by deVore and Slater, examines assays that are used in the quantification and standardization of allergens that are glycoproteins which elicit allergic reactions in susceptible individuals. Chapter 106, by Damin and Peebles, examines in vivo confirmatory assays for the detection of allergen-specific IgE antibody in patients suspected of having allergic disease. Chapter 107, by Hamilton, examines the diagnostic analytes that are measured in the diagnostic allergy clinical and research laboratory to aid in the diagnosis and management of human allergic disease. Chapter 108, by Schroeder and Saini, overviews mediators and markers of inflammation that are associated with immediate-type hypersensitivity reactions. Chapter 109, by Fleischer and Wood, discusses diagnostic tests that are useful in the workup of food allergy. In chapter 110, Klion overviews the clinical features, pathogenesis, and variants of hypereosinophilic syndromes.

Citation: Saini S. 2006. Introduction, p 935-936. In Detrick B, Hamilton R, Folds J (ed), Manual of Molecular and Clinical Laboratory Immunology, 7th Edition. ASM Press, Washington, DC. doi: 10.1128/9781555815905.ch104

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References

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1. Bennich, H. H.,, K. Ishizaka,, S. G. Johansson,, D. S. Rowe,, D. R. Stanworth, and , W. D. Terry. 1968. Immunoglobulin E: a new class of human immunoglobulin. Immunology 3:323324.

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