1887

Chapter 135 : Histocompatibility Testing after Fifty Years of Transplantation

MyBook is a cheap paperback edition of the original book and will be sold at uniform, low price.

Preview this chapter:
Zoom in
Zoomout

Histocompatibility Testing after Fifty Years of Transplantation, Page 1 of 2

| /docserver/preview/fulltext/10.1128/9781555815905/9781555813642_Chap135-1.gif /docserver/preview/fulltext/10.1128/9781555815905/9781555813642_Chap135-2.gif

Abstract:

Early attempts in human transplantation were limited by the immunosuppressive regimens which comprised primarily steroids, irradiation, and azathioprine. The development of clinical transplantation has fostered growth in understanding of the alloimmune response and of the major histocompatibility complex and in histocompatibility assessment. For much of the past 50 years of transplantation, the primary assay for histocompatibility testing, which can be used both for typing and for alloantibody detection, has been the complement-dependent cytotoxicity test. Molecular typing methods and solid-phase immunoassays are enabling histocompatibility laboratories to adapt testing to meet the changing needs of transplant patients. Three of the chapters in this section focus on the methods that are being used to monitor and evaluate transplant patients. For transplants with some degree of HLA mismatching, accurate determination of humoral sensitization is required to assess the risk of engraftment failure due to antibody-mediated rejection. The remaining chapters in this section address these newer issues for bone marrow and stem cell transplantation.

Citation: Leffell M. 2006. Histocompatibility Testing after Fifty Years of Transplantation, p 1195-1197. In Detrick B, Hamilton R, Folds J (ed), Manual of Molecular and Clinical Laboratory Immunology, 7th Edition. ASM Press, Washington, DC. doi: 10.1128/9781555815905.ch135

Key Concept Ranking

Major Histocompatibility Complex
0.6514297
Hematopoietic Stem Cell Transplantation
0.4581267
0.6514297
Highlighted Text: Show | Hide
Loading full text...

Full text loading...

References

/content/book/10.1128/9781555815905.ch135
1. Barker, J. N., and , J. E. Wagner. 2002. Umbilical cord blood transplantation: current state of the art. Curr. Opin. Oncol. 14:160164.
2. Barnard, C. H. 1967. A human cardiac transplantation interim report of a successful operation performed at Groote Schurr Hospital, Capetown. S. Afr. Med. J. 41:12711274.
3. Bensinger, W. I., and , R. Storb. 2001. Allogeneic peripheral blood stem cell transplantation. Rev. Clin. Exp. Hematol. 5:6786.
4. Bjorkman, P. J.,, M. A. Saper,, B. Samraoui,, W. S. Bennett,, J. L. Strominger, and , D. C. Wiley. 1987. Structure of the human class I histocompatibility antigen, HLA-A2. Nature 329:506512.
5. Borel, J. F.,, C. Feurer,, H. U. Gubler, and , H. Stahelin. 1994. Biological effects of cyclosporin A: a new antilym-phocytic agent. Agents Actions 43:179186. [Reprint of 1976 paper.]
6. Couzin, J. 2004. Putting tolerance to the test. Science 305:194196.
7. Dausset, J. 1954. Leuco-agglutinins. IV. Leuco-agglutinins and blood transfusion. Vox Sang 4:190198.
8. Delmonico, F. L. 2004. Exchanging kidneys—advances in living-donor transplantation. N. Engl. J. Med. 350:18121814.
9. Flomenberg, N.,, L. Baxter-Lowe,, D. Confer,, M. Fernandez-Vina,, A. Filipovich,, M. Horowitz,, C. Hurley,, C. Kollman,, C. Anasetti,, H. Noreen,, A. Begovich,, W. Hildebrand,, E. Petersdorf,, B. Schmeckpeper,, M. Setterholm,, E. Trachtenberg,, T. Williams,, E. Yunis, and , D. Weisdorf. 2004. Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome. Blood 104:19231930.
10. Hardy, J. D.,, W. R. Webb,, M. L. Dalton, Jr., and , G. R. Walker, Jr. 1963. Lung homotransplantation in man. JAMA 186:10651074.
11. Horowitz, M. M. 1999. Uses and growth of hematopoi-etic stem cell transplantation, p. 1218. In E. D. Thomas,, K. G. Blume, and , S. J. Forman (ed.), Hematopoietic Cell Transplantation, 2nd ed. Blackwell Sciences, Malden, Mass.
12. Jordan, S. C.,, A. Vo,, S. Bunnapradist,, M. Toyoda,, A. Peng,, D. Puliyanda,, E. Kamil, and , D. Tyan. 2003. Intravenous immune globulin treatment inhibits cross-match positivity and allows for successful transplantation of incompatible organs in living-donor and cadaver recipients. Transplantation 76:631636.
13. Khakoo, S. I.,, C. L. Thio,, M. P. Martin,, C. R. Brooks,, X. Gao,, J. Astemborski,, J. Cheng,, J. J. Goedert,, D. Vlahov,, M. Hilgartner,, S. Cox,, A. M. Little,, G. J. Alexander,, M. E. Cramp,, S. J. O’Brien,, W. M. Rosenberg,, D. L. Thomas, and , M. Carrington. 2004. HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection. Science 305:872874.
14. Kissmeyer-Nielsen, F.,, S. Olsen,, V. P. Peterson, and , O. Fjeldborg. 1966. Hyperacute rejection of kidney allo-grafts associated with pre-existing humoral antibodies against donor cells. Lancet ii:662665.
15. Leung, W.,, R. Iyengar,, V. Turner,, P. Lang,, P. Bader,, P. Conn,, D. Niethammer, and , R. Handgretinger. 2004. Determinants of antileukemia effects of allogeneic NK cells. J. Immunol. 172:644650.
16. Lillehei, R. C.,, Y. Idezuki,, W. D. Kelly,, J. S. Najarian,, F. K. Merkel, and , F. C. Goetz. 1969. Transplantation of the intestine and pancreas. Transplant. Proc. 1:230238.
17. Maris, M.,, B. M. Sandmaier,, D. G. Maloney,, P. A. McSweeney,, A. Wollfrey,, T. Chauncey,, J. Shizuru,, D. Niederwieser,, K. G. Blume,, S. Forman, and , R. Storb. 2001. Non-myeloablative hematopoietic stem cell transplantation. Transfus. Clin. Biol. 8:231234.
18. Merrill, J. P.,, J. E. Murray,, J. H. Harrison, and , W. R. Guild. 1956. Successful homotransplantation of the human kidney between identical twins. JAMA 160:277282.
19. Mittal, K. K.,, M. R. Mickey,, D. P. Singal, and , P. I. Terasaki. 1968. Serotyping for homotransplantation. 18. Refinement of microdroplet lymphocyte cytotoxicity test. Transplantation 6:913927.
20. National Marrow Donor Program. June 28, 2005, posting date. About the National Marrow Donor Program. [Online.] National Marrow Donor Program, Minneapolis, Minn. http://www.marrow.org/NMDP/.
21. Nelson, G. W.,, M. P. Martin,, D. Gladman,, J. Wade,, J. Trowsdale, and , M. Carrington. 2004. Cutting edge: heterozygote advantage in autoimmune disease: hierarchy of protection/susceptibility conferred by HLA and killer Ig-like receptor combinations in psoriatic arthritis. J. Immunol. 173:42734276.
22. Patel, R., and , P. I. Terasaki. 1969. Significance of the positive crossmatch test in kidney transplantation. N. Engl. J. Med. 280:735739.
23. Payne, R.,, M. Tripp,, J. Wiegle,, W. Bodmer, and , J. Bodmer. 1964. A new leukocyte isoantigenic system in man. Cold Spring Harbor Symp. Quant. Biol. 29:285.
24. Port, F. K.,, D. M. Dykstra,, R. M. Merion, and , R. A. Wolfe. 2004. Organ donation and transplantation trends in the USA, 2003. Am. J. Transplant. 4(Suppl. 9):712.
25. Ruggeri, L.,, M. Capanni,, E. Urbani,, K. Perruccio,, W. D. Shlomchik,, A. Tosti,, S. Posati,, D. Rogaia,, E. Frassoni,, F. Aversa,, M. F. Martelli, and , A. Velardi. 2002. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 295:20972100.
26. Slavin, S. 2001. Immunotherapy of cancer with alloreac-tive lymphocytes. Lancet Oncol. 2:491498.
27. Slavin, S.,, A. Nagler,, M. Y. Shapira,, M. Aker,, C. Gabriel, and , R. Or. 2002. Treatment of leukemia by alloreactive lymphocytes and nonmyeolablative stem cell transplantation. J. Clin. Immunol. 22:6469.
28. Starzl, T. E.,, C. G. Groth,, L. Brettschneider,, I. Penn,, V. A. Fulginiti,, J. B. Moon,, H. Blanchard,, A. J. Martin, Jr., and , K. A. Porter. 1968. Orthotopic homotransplantation of the human liver. Ann. Surg. 168:392415.
29. U.S. Department of Health and Human Services. 2003. Annual Report of the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients: Transplant Data 1993-2002. Department of Health and Human Services, Health Resources and Services Administration, Office of Special Programs, Division of Transplantation, Rockville, Md.; United Network for Organ Sharing, Richmond, Va.; University Renal Research and Education Association, Ann Arbor, Mich.
30. Williams, G. M.,, D. M. Hume,, R. P. Hudson, Jr.,, P. J. Morris,, K. Kano, and , F. Milgrom. 1968. “Hyperacute” renal-homograft rejection in man. N. Engl. J. Med. 279:611618.
31. Zachary, A. A.,, R. A. Montgomery,, L. E. Ratner,, M. Samaniego-Picotta,, D. Kopchaliiska, and , M. S. Leffell. 2003. Specific and durable elimination of antibody to donor HLA antigens in renal transplant patients. Transplantation 76:151925.

This is a required field
Please enter a valid email address
Please check the format of the address you have entered.
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error