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Antimicrobial Agents: Antibacterials and Antifungals

Editor: André Bryskier, M.D.1
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Affiliations: 1: Director, Clinical Pharmacology of Anti-infectives Sanofi-Aventis Romainville, France
Content Type: Reference
Format: Hardcover, Electronic
Publication Year: 2005

Category: Bacterial Pathogenesis

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is a significant revision of an original French reference published by Ellipses in 1999. Featuring more than 1,200 illustrations, over 1,500 tables, and more than 3,000 references, this major new volume comprehensively covers the history, chemistry, synthesis, mechanisms of action, pharmacology, and efficacy of all antimicrobial agents.

Written by experts, opens with foundational material covering the history of antibacterial chemotherapy, the system of classifying antimicrobial agents, the epidemiology of resistance, and the development of an antibiotic. The body of the text is divided into antimicrobial classes, including new chapters that extensively cover and methicillin-resistant . Also examined are antimicrobial agents that are in advanced states of development, products that are used on animals, agents that are as yet unexplored, and those for which development has ceased. All existing chapters have been thoroughly updated to reflect advances in technology and research since the publication of the first edition.

Unmatched in depth and scope of coverage, the new edition of is the reference source for physicians, microbiologists, chemists, pharmacologists, research scientists, and all others involved in antimicrobial research and development.

There are no separately available contributors for this publication.

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Doody Enterprises

15 August 2013

At A Glance

Antimicrobial Agents: Antibacterials and Antifungals is a significant revision of an original French reference published by Ellipses in 1999. Featuring more than 1,200 illustrations, over 1,500 tables, and more than 3,000 references, this major new volume comprehensively covers the history, chemistry, synthesis, mechanisms of action, pharmacology, and efficacy of all antimicrobial agents. Unmatched in depth and scope of coverage, the new edition of Antimicrobial Agents: Antibacterials and Antifungals is the reference source for physicians, microbiologists, chemists, pharmacologists, research scientists, and all others involved in antimicrobial research and development.

Description

This is a comprehensive reference on antibiotics and antifungal agents. The chapters are arranged in a systematic fashion and cover each class of antibiotics as well as the mechanism of antibiotic resistance.

Purpose

According to the author, the purpose is to "bring together as much information as possible on the subject of antimicrobial agents." He has accomplished this purpose and this is a remarkable reference book! I am not aware of another publication with so much information on antimicrobial agents.

Audience

This is a book that should be used by all individuals studying, testing, or prescribing antibiotics. The authors studiously explain each antibiotic by structure, function, metabolic activity, and antimicrobial mechanism of action. They also look at the antibiotic from the bacterial view, thus explaining how antibiotic resistance occurs. In addition, new drugs under development are evaluated by comparison with antibiotics currently in use. This is a treasure trove of useful information.

Features

This book will become the ultimate reference for understanding antibiotics. The first few chapters summarize the history of antibiotic development and the different antibiotic classes. The remaining chapters systematically detail the various classes of antibiotics. Numerous figures show the structure of the antimicrobial molecules and how the structure is modified as new agents are generated. As I read through the first chapters, I was reminded again of the great miracle that antibiotics provide to mankind and the great scientists that committed themselves to this endeavor. We must use the information in this book to go forward with the struggle to overcome bacterial resistance to antibiotics.

Assessment

This is a second edition of a book that was first published in French. I would highly recommend to the large audience of scientists who study antimicrobial agents. As we move from the era of antibiotic development to antibiotic resistance, a complete understanding of these agents and the history behind their development is needed. This book will become the "go-to" reference for researchers, pharmacists, pharmacologists, microbiologists, and infectious disease physicians as we struggle to fight antibiotic resistance.

Doody Enterprises

Reviewer: Rebecca Horvat, PhD, D(ABMM) (University of Kansas Medical Center)

Review Date: Unknown

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