1887

Chapter 11 : Future Trends in Control of Neglected Tropical Diseases and the Antipoverty Vaccines

MyBook is a cheap paperback edition of the original book and will be sold at uniform, low price.

Ebook: Choose a downloadable PDF or ePub file. Chapter is a downloadable PDF file. File must be downloaded within 48 hours of purchase

Buy this Chapter
Digital (?) $7.00

Preview this chapter:
Zoom in
Zoomout

Future Trends in Control of Neglected Tropical Diseases and the Antipoverty Vaccines, Page 1 of 2

| /docserver/preview/fulltext/10.1128/9781555816339/9781555816711_Chap11-1.gif /docserver/preview/fulltext/10.1128/9781555816339/9781555816711_Chap11-2.gif

Abstract:

The seven most prevalent neglected tropical diseases (NTDs) (in order of prevalence, they are ascariasis, trichuriasis, hookworm infection, schistosomiasis, lymphatic filiarisis [LF], trachoma, and onchocerciasis) are the most common infections of the world's poorest people. The major product development partnerships (PDPs) for new kinetoplastid drugs are listed in the chapter. These PDPs are either exploiting just-finished genome projects for protozoan parasites, in order to identify potential drug targets, or are embarking on high-throughput screening and other traditional approaches to drug development and clinical testing. Some of these PDPs are supported partly by the Bill and Melinda Gates Foundation. Researchers have the technology in hand to develop new antipoverty drugs, vaccines, and diagnostics, but it is financial innovation that is most needed in order to promote institutions for conducting scale-up process development, manufacturing, and clinical testing and for securing global access for these new products. Within the last decade, several important NTD PDPs have been established for research, development, and clinical testing of new drugs for Chagas' disease, human African trypanosomiasis, and leishmaniasis. At least five PDPs have also successfully developed NTD vaccines, also known as antipoverty vaccines, for clinical testing.

Citation: Hotez, M.D., Ph.D. P. 2008. Future Trends in Control of Neglected Tropical Diseases and the Antipoverty Vaccines, p 143-155. In Forgotten People, Forgotten Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555816339.ch11

Key Concept Ranking

Human African Trypanosomiasis
0.4050536
0.4050536
Highlighted Text: Show | Hide
Loading full text...

Full text loading...

References

/content/book/10.1128/9781555816339.ch11

Tables

Generic image for table
Table 11.1

New drugs developed between 1975 and 2004 specifically targeting NTDs

Citation: Hotez, M.D., Ph.D. P. 2008. Future Trends in Control of Neglected Tropical Diseases and the Antipoverty Vaccines, p 143-155. In Forgotten People, Forgotten Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555816339.ch11
Generic image for table
Table 11.2

PDPs for new drugs to treat human kinetoplastid infections

Citation: Hotez, M.D., Ph.D. P. 2008. Future Trends in Control of Neglected Tropical Diseases and the Antipoverty Vaccines, p 143-155. In Forgotten People, Forgotten Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555816339.ch11
Generic image for table
Table 11.3

PDPs for antipoverty vaccines to combat NTDs

Citation: Hotez, M.D., Ph.D. P. 2008. Future Trends in Control of Neglected Tropical Diseases and the Antipoverty Vaccines, p 143-155. In Forgotten People, Forgotten Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555816339.ch11

This is a required field
Please enter a valid email address
Please check the format of the address you have entered.
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error