1887

Antisepsis, Disinfection, and Sterilization: Types, Action, and Resistance

Author: Gerald E. McDonnell1
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Affiliations: 1: Vice President of Research and EMEA Affairs STERIS Limited

Basingstoke, Hampshire, United Kingdom
Content Type: Monograph
Format: Electronic
Publication Year: 2007

Category: Industrial Microbiology; Clinical Microbiology

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The new title examines the various chemical and physical antisepsis, disinfection, and sterilization methods used for infection prevention and contamination control. Targeting microbiologists, chemists, facilities managers, health care professionals, infection and contamination control practitioners, application engineers, and students, is a valuable reference written by an acknowledged expert working in the field.

The book provides descriptive background material covering the applications and various chemical and physical processes used for microbial control. An array of biocides is described, and the variables affecting their safe and effective use are detailed. The advantages, disadvantages, limitations, and correct applications of biocides and biocidal processes are discussed as well.

The mechanisms of biocidal action on microorganisms are investigated, including an examination of the less-studied intrinsic and acquired mechanisms of resistance in viruses, prions, protozoa, and fungi. Further considerations are given to the mechanisms on intrinsic and acquired resistance to biocides and biocidal processes, including cross-resistance to antibiotics in bacteria and novel mechanisms in extremophiles.

There are no separately available contributors for this publication.

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Microbiology Today

14 August 2013

This book is unique in his field as it is pitched between a student hand book and a book for professionals. G.E. McDonnell manages successfully to combine in a clear readable manner basic information on a wide of micro-organisms and up-to-date practical information on disinfection, antisepsis and sterilization. The main chapters are structured in a logical way and include background information, practical information(such as current standard protocols) and theoretical information, which allow a clear understanding of the principles and usage of these processes. The last chapters on mechanisms of action and microbial resistance are more academic in nature, but reflect accurately the rapidly growing, and much needed, interests to understand better the interactions between antisepsis/disinfection/sterilization processes and microorganisms. This book will appeal to a broad audience, in particular to students and professionals that have an interest in antisepsis, disinfection and sterilization but have a limited knowledge of microbiology.

Society for General Microbiology: Microbiology Today

Reviewer: Jean-Yves Maillard, Cardiff University

Review Date: Unknown

Doody Enterprises

14 August 2013

At A Glance

This new title examines the various chemical and physical antisepsis, disinfection, and sterilization methods used for infection prevention and contamination control. Targeting microbiologists, chemists, facilities managers, health care professionals, infection and contamination control practitioners, application engineers, and students. Antisepsis, Disinfection, and Sterilization is a valuable reference written by acknowledged expert working in the field.

Description

This comprehensive review of the various chemical and physical antisepsis, disinfection, and sterilization methods discusses the current understanding of mechanisms of biocide action on microorganisms. The last and most lengthy chapter describes the current knowledge of biocide resistance in bacteria, and the less studied mechanisms of resistance in viruses, prions, fungi, and eukaryotes.

Purpose

The book is intended to provide a basic understanding of the various chemical and physical antisepsis, disinfection, and sterilization methods used for infection prevention and contamination control. The author succeeds in providing a comprehensive review of the types, actions, and practical uses of the available biocidal methods.

Audience

It is targeted at healthcare professionals involved in infection control and prevention, application engineers, facilities managers, microbiologists, chemists, and students. The author is an acknowledged expert working in the field.

Features

A general introduction provides a review of terminology, definitions, and a background of pertinent microbiology. An array of physical and chemical agents are described, including specific types, practical uses, spectrum of activity, and variables affecting their safe and effective use. The mechanisms of action of biocides are covered in four general groups: oxidizing agents, cross-linking agents, action by transfer of energy, and other structure-disrupting agents. Current knowledge of the natural and acquired mechanisms that microorganisms employ to resist the biocidal effects of chemical and physical processes is explored.

Assessment

Students and healthcare professionals of infection control, microbiology, and public health will be able to use this as a reliable reference for the various chemical and physical antisepsis, disinfection, and sterilization methods. The book will provide a greater understanding and appreciation of these technologies used in contamination and infection prevention. In return, this will help ensure their long-term safe and effective use.

Doody Enterprises

Reviewer: Robert Penn, MD (Nebraska Methodist Hospital)

Review Date: Unknown

©Doody’s Review Service

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