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Chapter 10 : Crimean-Congo Hemorrhagic Fever
Category: Clinical Microbiology
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Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral zoonosis widely distributed in Africa, Asia, and Eastern Europe within the range of ticks belonging to the genus Hyalomma. It causes mild fever and viremia in cattle, sheep, and small mammals such as hares. Humans become infected by contact with infected blood or other tissues of livestock or human patients or from tick bites. CCHF virus is classified as a member of the genus Nairovirus, of the family Bunyavirida. The genus, consisting of 33 viruses, is divided into seven serogroups on the basis of antigenic relationships. This chapter first discusses the etiologic agent, biology, life cycle and zoonotic hosts of CCHF virus. Then, it talks about epidemiology, clinical manifestations, prevention, control, and treatment of CCHF.
Key Concept Ranking
- Hemorrhagic Fever With Renal Syndrome