Chapter 27 : Pathogenesis of Oral Streptococci

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Species of streptococci are well represented among the bacteria found in the oral cavity, which has been estimated to harbor around 500 different species of bacteria, though there remain many taxa of uncertain status and many microscopically observable microbes that have not yet been isolated in laboratory culture. These oral streptococci seem to be ubiquitous among all the human populations studied. When they have been sought, identical or closely related streptococci have also been found in a wide variety of animal species, so streptococci are clearly part of the normal commensal flora of mammals; this chapter considers the problems that arise when this commensal relationship breaks down and the oral streptococci become opportunistic pathogens. The chapter talks about acquisition of oral streptococci, mechanism of colonization, immunological processes in the mouth, and metabolism of dental plaque. The oral streptococci are normal commensals of the human mouth and as such play a beneficial role in colonization resistance, excluding potentially pathogenic species oral streptococci as pathogens, systemic infections, virulence factors of oral streptococci.

Citation: Russell R. 2006. Pathogenesis of Oral Streptococci, p 332-339. In Fischetti V, Novick R, Ferretti J, Portnoy D, Rood J (ed), Gram-Positive Pathogens, Second Edition. ASM Press, Washington, DC. doi: 10.1128/9781555816513.ch27

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Restriction Fragment Length Polymorphism
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Phylogenetic relationships among 34 species by 16S rRNA gene sequence analysis. (Reproduced from Kawamura et al. [ ] with permission.)

Citation: Russell R. 2006. Pathogenesis of Oral Streptococci, p 332-339. In Fischetti V, Novick R, Ferretti J, Portnoy D, Rood J (ed), Gram-Positive Pathogens, Second Edition. ASM Press, Washington, DC. doi: 10.1128/9781555816513.ch27
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Generic image for table

Streptococci commonly found in the human mouth

Citation: Russell R. 2006. Pathogenesis of Oral Streptococci, p 332-339. In Fischetti V, Novick R, Ferretti J, Portnoy D, Rood J (ed), Gram-Positive Pathogens, Second Edition. ASM Press, Washington, DC. doi: 10.1128/9781555816513.ch27

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