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Key Concept Ranking

Fungal Infections
Candida albicans
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1. Bain, B. J.,, D. M. Clark,, I. A. Lampert,, and B. S. Wilkins. 2001. Bone Marrow Pathology, 3rd ed., p. 99. Wiley-Blackwell, New York, NY.
2. Barenfanger, J.,, C. Drake,, J. Lawhorn,, and S. J. Verhulst. 2004. Comparison of chlorhexidine and tincture of iodine for skin antisepsis in preparation for blood culture collection. J. Clin. Microbiol. 42:22162217.
3. Baron, E. J.,, M. P. Weinstein,, W. M. Dunne, Jr.,, P. Yagupsky,, D. F. Welch,, and D. M. Wilson. 2005. Cumitech 1C, Blood cultures IV. Coordinating ed., E. J. Baron. ASM Press, Washington, DC.
4. Carrol, K.,, and L. Reimer. 1996. Microbiology and laboratory diagnosis of upper respiratory tract infections. Clin. Infect. Dis. 23:442448.
5. Chapin-Robertson, K.,, S. E. Dahlberg,, and S. C. Edberg. 1992. Clinical and laboratory analyses of cytospin-prepared Gram stains for recovery and diagnosis of bacteria from sterile body fluids. J. Clin. Microbiol. 30:377380.
6. Chern, K. C.,, D. M. Meisler,, K. R. Wilhelmus,, D. B. Jones,, G. A. Stern,, and C. Y. Lowder. 1996. Corneal anesthetic abuse and Candida keratitis. Ophthalmology 103:3740.
7. Chiarini, A.,, A. Palmeri,, T. Amato,, R. Immordino,, S. Distefano,, and A. Giammanco. 2008. Detection of bacterial and yeast species with the Bactec 9120 automated system with routine use of aerobic, anaerobic, and fungal media. J. Clin. Microbiol. 46:40294033.
8. Cimbaluk, D.,, J. Scudiere,, J. Butsch,, and S. Jakate. 2005. Invasive candidal enterocolitis followed shortly by fatal cerebral hemorrhage in immuno-compromised patients. J. Clin. Gastroenterol. 39:795797.
9. Cockerill, F. R., III,, J. W. Wilson,, E. A. Vetter,, K. M. Goodman,, C. A. Torgerson,, W. S. Harmsen,, C. D. Schleck,, D. M. Illstrup,, J. A. Washington III,, and W. R. Wilson. 2004. Optimal testing parameters for blood cultures. Clin. Infect. Dis. 38:17241730.
10. Cockerill, F. R., III,, C. A. Torgerson,, G. S. Reed,, E. A. Vetter,, A. L. Weaver,, J. C. Dale,, G. D. Roberts,, N. K. Henry,, D. M. Illstrup,, and J. E. Rosenblatt. 1996. Clinical comparison of Difco ESP, Wampole Isolator, and Becton Dickinson Septi-Chek aerobic blood culturing systems. J. Clin. Microbiol. 34:2024.
11. Creger, R. J.,, K. E. Weeman,, M. R. Jacobs,, A. Morrisey,, P. Parker,, R. M. Fox,, and H. M. Lazarus. 1998. Lack of utility of the lysis-centrifugation blood culture method for detection of fungemia in immunocompromised cancer patients. J. Clin. Microbiol. 36:290293.
12. Duong, S.,, B. J. Dezube,, G. Desai,, K. Eichelberger,, Q. Qian,, and J. E. Kirby. 2009. Limited utility of bone marrow culture: a ten-year retrospective analysis. Lab. Med. 40:3738.
13. Ellis, M. E.,, H. Al-Abdely,, A. Sandridge,, W. Greer,, and W. Ventura. 2001. Fungal endocarditis: evidence in the world literature. Clin. Infect. Dis. 32:5062.
14. Fisher, J. E.,, C. L. Newman,, and J. D. Sobel. 1995. Yeast in the urine: solutions for a budding problem. Clin. Infect. Dis. 20:183189.
15. Forbes, B. A.,, D. F. Sahm,, and A. S. Weissfeld. 2007. Bailey & Scott’s Diagnostic Microbiology, 12th ed., p. 778797. Mosby Elsevier, St. Louis, MO.
16. Forbes, B. A.,, D. F. Sahm,, and A. S. Weissfeld. 2007. Bailey & Scott’s Diagnostic Microbiology, 12th ed., p. 629713. Mosby Elsevier, St. Louis, MO.
17. Fraser, V. J.,, M. Jones,, and J. Dunkel. 1992. Candidemia in a tertiary care hospital: epidemiology, risk factors, and predictors of mortality. Clin. Infect. Dis. 15:414421.
18. Fricker-Hidalgo, H.,, B. Lebeau,, H. Pelloux,, and R. Grillot. 2004. Use of the BACTEC 9240 system with mycosis-IC/F blood culture bottles for detection of fungemia. J. Clin. Microbiol. 42:18551856.
19. Gaur, A. H.,, M. A. Giannini,, P. M. Flynn,, J. W. Boudreaux,, M. A. Mestemacher,, J. L. Shenep,, and T. Hayden. 2003. Optimizing blood culture practices in pediatric immunocompromised patients: evaluation of media types and blood culture volume. Pediatr. Infect. Dis. J. 22:545552.
20. Hazen, K. C., 1998. Section 6. Mycology and aerobic actinomycetes, p. 255283. In H. D. Isenberg (ed.), Essential Procedures for Clinical Microbiology. American Society for Microbiology, Washington, DC.
21. Hellinger, W. C.,, J. J. Cawley,, S. Alvarez,, S. F. Hogan,, W. S. Harmsen,, D. M. Ilstrup,, and F. R. Cockerill III. 1995. Clinical comparison of the Isolator and BacT/Alert aerobic blood culture systems. J. Clin. Microbiol. 33:17871790.
22. Hubbard, T. W.,, and J. M. de Triquet. 1992. Brush-culture method for diagnosing tinea capitis. Pediatrics 90:416418.
23.Joint Commission (JCAHO). 2009. IM.6.240. Clinical Laboratory Improvement Act Subpart K Sec. 493.1232, Sec. 493.1242, and Sec. 493.1249. Joint Commission, Oakbrook Terrace, IL.
24. Kellogg, J. A.,, J. P. Manzella,, and D. A. Bankert. 2000. Frequency of low-level bacteremia in children from birth to fifteen years of age. J. Clin. Microbiol. 38:21812185.
25. Kosmin, A. R.,, and T. Fekete. 2008. Use of fungal blood cultures in an academic medical center. J. Clin. Microbiol. 46:38003801.
26. Kouklakis, G.,, S. Dokas,, E. Molyvas,, P. Vakianis,, and A. Efthymiou. 2001. Candida colitis in a middle-aged male receiving permanent haemodialysis. Eur. J. Gastroenterol. Hepatol. 13:735736.
27. Kwon-Chung, K. J.,, and J. Bennett. 1992. Medical Mycology, p. 4546. Lea & Febiger, Philadelphia, PA.
28. Labarca, J. A.,, E. A. Wagar,, A. E. Grasmick,, H. M. Kokkinos,, and D. A. Bruckner. 1998. Critical evaluation of 4-week incubation for fungal cultures: is the fourth week useful? J. Clin. Microbiol. 35:36833685.
29. Larone, D. H. Medically Important Fungi: a Guide to Identification, 4th ed. ASM Press, Washington, DC.
30. Lee, A.,, S. Mirrett,, L. B. Reller,, and M. P. Weinstein. 2007. Detection of bloodstream infections in adults: how many blood cultures are needed? J. Clin. Microbiol. 45:35463548.
31. Maki, D. G.,, C. D. Weise,, and H. W. Sarafin. 1977. A semiquantitative culture method for identifying intravenouscatheter- related infection. N. Engl. J. Med. 296:13051309.
32. Mawhorter, S. D.,, G. V. Curley,, E. D. Kursh,, and C. E. Farver. 2000. Prostatic and central nervous system histoplasmosis in an immunocompetent host: case report and review of the prostatic histoplasmosis literature. Clin. Infect. Dis. 30:595598.
33. McGinnis, M. R. 1980. Laboratory Handbook of Medical Mycology. Academic Press, New York, NY.
34. Merz, W. G.,, and G. D. Roberts,. 1999. Detection and recovery of fungi from clinical specimens, p. 709722. In P. R. Murray et al. (ed.), Manual of Clinical Microbiology, 7th ed. American Society for Microbiology, Washington, DC.
35. Mess, T.,, and E. S. Daar. 1997. Utility of fungal blood cultures for patients with AIDS. Clin. Infect. Dis. 25:13501353.
36. Mirrett, S.,, L. B. Reller,, C. A. Petti,, C. W. Woods,, B. Vazirani,, R. Sivadas,, and M. P. Weinstein. 2003. Controlled clinical comparison of BacT/ALERT standard aerobic medium with BACTEC standard aerobic medium for culturing blood. J. Clin. Microbiol. 41:23912394.
37. Mirrett, S.,, K. E. Hanson,, and L. B. Reller. 2007. Controlled clinical comparison of VersaTREK and BacT/ALERT blood culture systems. J. Clin. Microbiol. 45:299302.
38. Morello, J. A.,, S. M. Matushek,, W. M. Dunne,, and D. B. Hinds. 1991. Performance of a BACTEC nonradiometric medium for pediatric blood cultures. J. Clin. Microbiol. 29:359362.
39. Morrell, R. M.,, B. L. Wasilauskas,, and C. H. Steffe. 1996. Performance of fungal blood cultures by using the Isolator collection system: is it cost effective? J. Clin. Microbiol. 34:30403043.
40. Musial, C. E.,, F. R. Cockerill III,, and G. D. Roberts. 1988. Fungal infections of the immunocompromised host: clinical and laboratory aspects. Clin. Microbiol. Rev. 1:349364.
41. Neal, P. M.,, and A. Nikolai. 2008. Systemic blastomycosis diagnosed by prostate needle biopsy. Clin. Med. Res. 6: 2428.
42. Petti, C. A.,, A. K. M. Zaidi,, S. Mirrett,, and L. B. Reller. 1996. Comparison of Isolator 1.5 and BACTEC NR660 aerobic 6A blood culture systems for detection of fungemia in children. J. Clin. Microbiol. 34:18771879.
43. Procop, G. W.,, F. R. Cockerill III,, E. A. Vetter,, W. S. Harmsen,, J. G. Hughes,, and G. D. Roberts. 2000. Performance of five agar media for recovery of fungi from Isolator blood cultures. J. Clin. Microbiol. 38:38273829.
44. Reimer, L. G.,, M. L. Wilson,, and M. P. Weinstein. 1997. Update on detection of bacteremia and fungemia. Clin. Microbiol. Rev. 10:444465.
45. Reimer, L. G.,, and K. C. Carroll. 1998. Role of the microbiology laboratory in the diagnosis of lower respiratory tract infections. Clin. Infect. Dis. 26:742748.
46. Richardson, M.,, and C. Lass-Flörl. 2008. Changing epidemiology of systemic fungal infections. Clin. Microbiol. Infect. 4(Suppl.):524.
46a. Scognamiglio, T.,, R. Zinchuk,, P. Gumpeni,, and D. H. Larone. 2010. Comparison of inhibitory mold agar to Sabouraud dextrose agar as a primary medium for isolation of fungi. J. Clin. Microbiol. 48:19241925.
47. Shanholtzer, C. J.,, P. J. Schaper,, and L. R. Peterson. 1982. Concentrated Gram stain smears prepared with a cytospin centrifuge. J. Clin. Microbiol. 16:10521056.
48. Sohail, M. R.,, P. E. Andrews,, and J. E. Blair 2005. Coccidioidomycosis of the male genital tract. J. Urol. 173:19781982.
49. Sonntag, H. G. 2002. Sampling and transport of specimens for microbial diagnosis of ocular infections. Dev. Ophthalmol. 33:362367.
50. Sutton, D. A., 2007. Specimen collection, transport, and processing: mycology, p. 17281736. In P. R. Murray,, E. J. Baron,, J. H. Jorgensen,, M. L. Landry,, and M. A. Pfaller (ed.), Manual of Clinical Microbiology, 9th ed. American Society for Microbiology, Washington, DC.
51. Szymzcak, E. G.,, J. T. Barr,, W. A. Durbin,, and D. A. Goldman. 1979. Evaluation of blood culture procedures in a paediatric hospital. J. Clin. Microbiol. 9:8892.
52. Tanure, M. A.,, E. J. Cohen,, S. Sudesh,, C. J. Rapuano,, and P. R. Laibson. 2000. Spectrum of fungal keratitis at Wills Eye Hospital, Philadelphia, Pennsylvania. Cornea 19:307312.
53. Telenti, A.,, and G. D. Roberts. 1989. Fungal blood cultures. Eur. J. Clin. Microbiol. Infect. Dis. 8:825831.
54. Washington, J. A., II,, and D. M. Illstrup. 1986. Blood cultures: issues and controversies. Rev. Infect. Dis. 8:792802.
55. Watts, B.,, P. Argekar,, S. Saint,, and C. A. Kauffman. 2007. Clinical problem-solving. Building a diagnosis from the ground up—a 49-year-old man came to the clinic with a 1-week history of suprapubic pain and fever. N. Engl. J. Med. 356:14561462.
56. Witebsky, F. G.,, and V. J. Gill. 1995. Fungal blood culture systems: which ones and when to use them. Clin. Microbiol. Newsl. 17:161163.
57. Wolf, J.,, and A. Daley. 2007. Microbiological aspects of bacterial lower respiratory tract illness in children: typical pathogens. Paediatr. Respir. Rev. 8:204211.
58. Yurkanin, J. P.,, F. Ahmann,, and B. L. Dalkin. 2006. Coccidioidomycosis of the prostate: a determination of incidence, report of 4 cases, and treatment recommendations. J. Infect. 52:e19e25.


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Specimen collection and transport guidelines

Abbreviations: BAL, bronchoalveolar lavage fluid; CSF, cerebrospinal fluid; RT, room temperature.

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Common clinical sites for laboratory recovery of pathogenic fungi

X, recovery of fungus from indicated tissue.

Includes skin and mucous membranes.

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Pretreatment of clinical specimens prior to plating

-Acetyl-l-cysteine, 5% oxalic acid, or dithiothreitol (Sputolysin).

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Media suggested for the recovery of fungi from clinical specimens

Abbreviations: BHI, brain heart infusion agar; SDA, Sabouraud dextrose agar; Sabhi medium, Sabouraud dextrose and brain heart infusion agar; IMA, inhibitory mold agar; DTM, dermatophyte test medium; DIM, dermatophyte identification medium; CMA, cornmeal agar; PDA, potato dextrose agar; PFA, potato flake agar; RSA, rapid sporulation agar; EBM, esculin base medium.


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