1887

Chapter 1 : From Breathing Bad Air to Biting Beasts

MyBook is a cheap paperback edition of the original book and will be sold at uniform, low price.

Ebook: Choose a downloadable PDF or ePub file. Chapter is a downloadable PDF file. File must be downloaded within 48 hours of purchase

Buy this Chapter
Digital (?) $7.00

Preview this chapter:
Zoom in
Zoomout

From Breathing Bad Air to Biting Beasts, Page 1 of 2

| /docserver/preview/fulltext/10.1128/9781555816889/9781555819095_Chap01-1.gif /docserver/preview/fulltext/10.1128/9781555816889/9781555819095_Chap01-2.gif

Abstract:

Malaria is also called ague, intermittent fever, marsh fever, Roman fever, or simply The Fever. It was believed that the fever recurred during the sickly summer season due to vapors emanating from the marshes, hence the name “malaria” (literally “bad air”). Ronald Ross’s discovery of infectious stages in the mosquito salivary glands in bird malaria appeared to be the critical element in understanding transmission of the disease in humans. After discovering the mosquito as a vector for Plasmodium, Ross presumed that once the inoculated parasites (called sporozoites) had entered the bloodstream they burrowed straightaway into red blood cells. Giovanni Battista Grassi recognized that insofar as malaria was concerned there remained two main tasks: to demonstrate the developmental cycle of the human parasite in the mosquito and to identify the kind of mosquito that transmitted human malaria. There are four kinds of human malaria parasites, , , , and , with three developmental stages (in the blood, in the mosquito, and in the liver). Each of these could be a potential target for drug therapy. Medicines developed against the various stages could serve to break the cycle of transmission, prevent relapses, and, minimize or eliminate entirely the pathologic effects of the rapidly multiplying stages in the blood.

Citation: Sherman I. 2011. From Breathing Bad Air to Biting Beasts, p 1-22. In Magic Bullets to Conquer Malaria. ASM Press, Washington, DC. doi: 10.1128/9781555816889.ch1

Key Concept Ranking

Blood Infections
0.42588475
0.42588475
Highlighted Text: Show | Hide
Loading full text...

Full text loading...

Figures

Image of Figure 1
Figure 1

The life cycle of the human malaria parasite .

Citation: Sherman I. 2011. From Breathing Bad Air to Biting Beasts, p 1-22. In Magic Bullets to Conquer Malaria. ASM Press, Washington, DC. doi: 10.1128/9781555816889.ch1
Permissions and Reprints Request Permissions
Download as Powerpoint

References

/content/book/10.1128/9781555816889.ch01

This is a required field
Please enter a valid email address
Please check the format of the address you have entered.
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error