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Chapter 9 : Escherichia coli O157:H7

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Escherichia coli O157:H7, Page 1 of 2

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Abstract:

O157:H7 can cause nonbloody diarrhea, bloody diarrhea (hemorrhagic colitis), hemolytic uremic syndrome (HUS), thrombotic thrombocytopenic purpura (TIP), and death. Illness typically begins with severe abdominal cramps and nonbloody diarrhea, which often becomes bloody by the second or third day of illness. Thus, although bloody stools are common with O157:H7 infection, the diagnosis must be considered for patients with nonbloody diarrhea as well. Differential diagnosis of colitis caused by O157:H7 have been provided in this chapter. Probably the most common cause of acute renal failure in children, HUS is characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal failure, and central nervous system manifestations. Most information about modes of transmission of O157:H7 infection has been derived from outbreak investigations. Although most O157:H7 strains are susceptible to antimicrobial agents used for enteric infections, such treatment has not been demonstrated to improve the course of illness or to prevent complications. The authors recommend that clinicians urge their clinical laboratories to culture for O157:H7 by using sorbitol-MacConkey medium, at a minimum from stools with visible blood. They should advise patients with diarrhea and parents of children with diarrhea that washing hands with soap after bowel movements is the most important measure in preventing the spread of infection.

Citation: Griffin P, Boyce T. 1998. Escherichia coli O157:H7, p 137-146. In Scheld W, Armstrong D, Hughes J (ed), Emerging Infections 1. ASM Press, Washington, DC. doi: 10.1128/9781555816940.ch9

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Shiga Toxin 1
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Shiga Toxin 2
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References

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1. Ashkenazi, S. 1993. Role of bacterial cytotoxins in hemolytic uremic syndrome and thrombotic thrombocytopenic purpura. Annu. Rev. Med. 44:1118.
2. Banatvala, N.,, M. M. DeBeukelaer,, P. M. Griffin,, T. J. Barrett,, K. D. Greene,, J. H. Green,, and J. G. Wells. 1996. Shiga-like toxin-producing Escherichia coli 0 III and associated hemolyticuremic syndrome: a family outbreak. Pediatr. Infect. Dis. J. 15:10081011.
3. Barrett, T. J.,, J. H. Green,, P. M. Griffin,, A. T. Pavia,, S. M. Ostroff,, and I. K. Wachsmuth. 1991. Enzyme•linked immunosorbent assays for detecting antibodies to Shiga-like toxin I, Shigalike toxin II, and Escherichia coli 0157:H7 lipopolysaccharide in human serum. Curr Microbial. 23:189195.
4. Bell, B. P.,, M. Goldoft,, P. M. Griffin,, M. A. Davis,, D. C. Gordon,, P. I. Tarr,, C. A. Bartleson,, J. H. Lewis,, T. J. Barrett,, J. G. Wells,, R. Baron,, and J. Kobayashi. 1994. A multistate outbreak of Escherichia coli 01 57:H7-associated bloody diarrhea and hemolytic uremic syndrome from ham• burgers: the Washington experience. JAMA 272:13491353.
5. Bokete, T. N.,, C. M. O'Caliahan,, C. R. Clausen,, N. M. Tang,, N. Tran,, S. L. Moseley,, T. R. Fritsche,, and P. I. Tarr. 1993. Shiga-like toxin-producing Escherichia coli in Seattle children: a prospective study. Gastroenterology 105:17241731.
6. Boyce, T. G.,, A. G. Pemberton,, J. G. Wells,, and P. M. Griffin. 1995. Screening for Escherichia coli 0157:H7-a nationwide survey of clinical laboratories. J. Clin. Microbial. 33:32753277.
7. Boyce, T. G.,, D. L. Swerdlow,, and P. M. Griffin. 1995. Escherichia coli 0I57:H7 and the hemolytic uremic syndrome. N. Engl. J. Med. 333:364368.
8. Bryant, H. E.,, M. A. Athar,, and C. H. Pal. 1989. Risk factors for Escherichia coli 0157:H7 infection in an urban community. J. Infect. Dis. 160:858864.
9. Cahoon, F. E., and J. S. Thompson. 1987. Frequency of Escherichia coli 0157:H7 isolation from stool specimens. J. Infect. Dis. 33:914915.
10. Calderwood, S. B.,, D. W. K. Acheson,, G. T. Keusch,, T. J. Barrett,, P. M. Griffin,, N. A. Strock• bine,, B. Swaminathan,, J. B. Kaper,, M. M. Levine,, B. S. Kaplan,, H. Karch,, A. D. O'Brien,, T. G. Obrig,, Y. Takeda,, P. I. Tarr,, and I. K. Wachsmuth. 1996. Proposed new nomenclature for SLT (VT) family. ASM News 62:118119.
11.. Caprioli, A.,, I. Luzzi,, F. Rosmini,, C. Resti,, A. Edefonti,, F. Perfumo,, C. Farina,, A. Goglio,, A. Gianviti,, and G. Rizzoni. 1994. Community•wide outbreak of hemolytic-uremic syndrome associated with non-0157 verocytotoxin-producing Escherichia coli. J. Infect. Dis. 169:208211.
12. Carter, A. 0., A. A. Borc2yk, J. A. K. Carlson, B. Harvey, J. C. Hockin, M. A. Karmali, C. Krishnan, D. A. Korn, and H. Lior. 1987. A severe outbreak of Escherichia coli 0157:H7-associated hemorrhagic colitis in a nursing home. N. Engl. J. Med. 317:14961500.
13..Centers for Disease Control and Prevention. 1995. Outbreak of acute gastroenteritis attributable to Escherichia coli serotype 0104:H21-Helena. Montana. 1994. Morbid. Mortal. Weekly Rep. 44:501Æ503.
14..Centers for Disease Control and Prevention. 1995. Community outbreak of hemolytic uremic syndrome attributable to Escherichia coli 0111:NM-South Australia, 1995 Morbid. Mortal. Weekly Rep. 44:550Æ558.
15. Chapman, P. A. 1989. Evaluation of commercial latex slide test for identifying Escherichia coli 0157. J. Clin. Pathol. 42:11091110.
16. Chapman, P. A.,, C. A. Siddons,, A. T. C. Malo,, and M. A. Harkin. 1994. Lamb products as a potential source of E. coli 0157. Vet. Rec. 139:427428.
17. Cimolai, N.,, S. Basalyga,, D. G. Mah,, B. J. Morrison,, and J. E. Carter. 1994. A continuing assessment of risk factors for the development of Escherichia coli 0157:H7-associated hemolytic uremic syndrome. Clin. Nephrol. 42:8589.
18. Cimolai, N.,, J. E. Carter,, B. J. Morrison,, and J. D. Anderson. 1990. Risk factors for the progression of Escherichia coli 0157:H7 enteritis to hemolytic-uremic syndrome. J. Pediatr. 116:589592.
19. Goldwater, P. N.,, and K. A. Bettelheim. 1996. An outbreak of hemolytic uremic syndrome due to Escherichia coli 01 57:H-: or was it? Emerg. Infect. Dis. 2:153154.
20. Gransden, W. R.,, M. A. Damm,, J. D. Anderson,, J. E. Carter,, and H. Lior. 1986. Further evidence associating hemolytic uremic: syndrome with infection by verotoxin-producing Escherichia coli 0157:H7. J Infect. Dis. 154:522524.
21. Griffin, P. M., 1995. Escherichia coli 0157:H7 and other enterohemorrhagic Escherichia coli, p. 739761. In M. J. Blaser,, P. D. Smith,, J. I. Ravdin,, H. B. Greenberg,, and R. L. Guerrant (ed.). Infections of the Gastrointestinal Tract. Raven Press, Ltd., New York, N.Y..
22. Griffin, P. M.,, B. P. Bell,, P. R. Cieslak,, J. Thttle,, T. J . Barrett,, M. P. Doyle,, A. M. McNamara,, A. M. Shefer,, and J. G. Wells,. 1994. Large outbreak of Escherichia coli 0157:H7 infections in the western United States: the big pictu re, p. 712. In M. A. Karmali, and A. G. Goglio (ed.). Recent Advance.f in Ve rocytotoxin -Producing Escherichia coli Infections. Elsevier, New York, N.Y..
23. Griffin, P. M.,, S. M. Ostroff,, R. V. Tauxe,, K. D. Greene,, J. G. Wells,, J. H. Lewis,, and P. A. Blake. 1988. Illnesses associated with Es(•herichia coli 0 157:H7 infections: a broad clinical spectrum. Ann. Intern. Med. 109:705712.
24. Griffin, P. M., and R. V. Tauxe. 1991. The epidemiology of infections caused by Escherichia coli 0 157:H7, other enterohemorrhagic E. coli, and the associated hemolytic uremic syndrome. Epidemiol. Rev. 13:6098.
25. Itoh, T.,, A. Kai,, K. Saito,, Y. Yanagawa,, M. Inaba,, M. Takahashi,, Y. Kudoh,, S. Yamada,, S. Matsushita,, T. Terayama,, and M. Ohashi,. 1988. Gastroenteritis associated with verocytolOxin producing Escherichia coli 0 145:NM. p. 2128. In S. Kuwahara, and N. F. Pierce (cd.). Advances in Research on Cholera and Related Diarrheas. KTK Scientific Publishers, Tokyo, Japan.
26. Karmali, M. A.,, M. Petrie,, C. Lim,, P. C. Fleming,, G. S. Arbus,, and H. Lior. 1985. The asso• dation between idiopathic hemolytic uremic syndrome and infection by verotoxin•producing Escherichia coli. J. Infect. Dis. 151:775782.
27. Keene, W. E.,, J. Kok,, E. Sazie,, V. K. Balan,, D. H. Rice,, and D. D. Hancock. 1996. An outbreak of Escherichia coli 0 157:H7 infections traced to a novel source: black•tailed deer, abstr. K152, p.277. In Abstracts of the 36th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology. Washington, D.C..
28. Kudva, I. T.,, P. G. Hatfield,, and C. J. Hovde. 1996. Escherichia c:oli 0157:H7 in microbial flora of sheep. J. Clin. Microbial. 34:431433.
29. MacDonald, K. L.,, M. J. O'Leary,, M. L. Cohen,, P. Norris,, J. G. Wells,, E. Noll,, J. M. Kobayashi,, and P. A. Blake. 1988. Escherichia coli OI 57: H7, an emerging gastrointestinal pathogen: results of a one-year, prospective, population-based study. JAMA 259:35673570.
30. March, S. B.,, and S. Ratnam. 1986. Sorbitol-MacConkey medium for detection of Escherichia coli 0157:H7 associated with hemorrhagic colitis. J. Clin. Microhiol. 23:869872.
31. Marshall, W. F.,, C. A. McLimans,, R. E. Van Scoy,, and J. P. Anhalt. 1990. Results of a 6•month survey of stool cultures for Escherichia coli 0 157:H7. Mayo Clin. Proc. 65:787792.
32. Martin, D. L.,, K. L. MacDonald,, K. E. White,, J. T. Soler,, and M. T. Osterholm. 1990. The epidemiology and clinical aspects of the hemolytic uremic syndrome in Minnesota. N. Engl. J. Med. 323:11611167.
33. Ostroff, S. M.,, P. M. Griffin,, R. V. Tauxe,, L. D. Shipman,, K. D. Greene,, J. G. Wells,, J. H. Lewis,, P. A. Blake,, and J. M. Kobayashi. 1990. A statewide outbreak of Escherichia wli 0157: H7 infections in Washington State. Am. J. Epidemiol. 132:239247.
34. Ostroff, S. M.,, J. M. Kobayashi,, and J. H. Lewis. 1989. In fections with Escherichia coli 0157:H7 in Washington State: the first year of statewide disease surveillance. JAMA 262:355359.
35. Pai, C. H.,, N. Ahmed,, H. Lior,, W. M. Johnson,, H. V. Sims,, and D. E. Woods. 1988. Epidemiology of sporadic diarrhea due to verocytotox in -producing Escherichia coli: a two-year prospective study. J. Infect. Dis. 157:10541057.
36. Pai, C. H.,, R. Gordon,, H. V. Sims,, and L. E. Bryan. 1984. Sporad ic cases of hemorrhagic colitis associated with Escherichia coli 01 57:H7: clinical. epidemiologic, and bacteriologic features. Ann. Intern. Med. 101:738742.
37. Park, C. H.,, D. L. Hixon,, W. L. Morrison,, and C. B. Cook. 1994. Rapid diagnosis of enterohemorrhagic Escherichia coli 0157:H7 directly from fecal specimens using immunofluorescence stain. Am. J. Clin. Pathol. 101:9194.
38. Pavia, A. T.,, C. R. Nichols,, D. P. Green,, R. V. Tauxe,, S. Mottiee,, K. D. Greene,, J . G. Wells,, R. L. Siegler,, E. D. Brewer,, D. Hannon,, and P. A. Blake. 1990. Hemolytic-uremic syndrome during an outbreak of Escherichia coli 0157:H7 infections in institutions for mentally retarded persons: clinical and epidemiologic observalions. J. Pediatr. 116:544551.
39. Pickering, L. K.,, T. G. Obrig,, and F. B. Stapleton. 1994. Hemolytic-uremic syndrome and enlerohemorrhagic Escherichia coli. Pediatr. Infect. Dis. J. 13:459476.
40. Proulx, F.,, J. P. Turgeon,, G. Delage,, L. Lafleur,, and L. Chicoine. 1992. Randomized. controlled trial of antibiotic therapy for Esdlerichia coli 0157:H7 enteritis. J. Pediatr. 121:299303.
41. Ratnam, S.,, and S. B. March. 1986. Sporadic occurrence of hemorrhagic colitis associated with Escherichia coli 0157:H7 in Newfoundland. Can. Med. Assoc. J. 134:4346.
42. Riley, L. W.,, R. S. Remis,, S. D. Helgerson,, H. B. McGee,, J. G. Wells,, B. R. Davis,, R. J. Hebert,, E. S. Olcott,, L. M. Johnson,, N. T. Hargrett,, P. A. Blake,, and M. L. Cohen. 1983. Hemorrhagic colitis associated with a rare Escherichia coli serotype. N. Engl. J. Med. 308:681685.
43. Rowe, P. C.,, E. Orrbinc,, M. Ogborn,, G. A. Wells,, W. Winther,, H. Lior,, D. Manuel,, and P. N. McLaine. 1994. Epidemic Escherichia coli 0157:H7 gastroemeritis and hemolytic-uremic syndrome in a Canadian Inuil community: intestinal illness in family members as a risk factor. J. Pediatr. 124:2126.
44. Ruggenenti, P.,, and G. Remuzzi. 1990. Thrombotic thrombocylopenic purpura and relaled disorders. Hematol.Oncol. Clin. North Am. 4:219241.
45. Shah, S.,, R. Hoffman,, P. Shillam,, and B. Wilson. 1996. Prolonged fecal shedding of Escherichia coli 0157:H7 during an outbreak at a day care center. Clin. Infect. Dis. 23:835836.
46. Siegler, R. L.,, A. T. Pavia,, R. D. ChristolTerson,, and M. K. Milligan. 1994. A 20•year population• based study of postdiarrheal hemolytic uremic syndrome in Utah. Pediatrics 94:3540.
47. Slutsker, L.,, A. A. Ries,, K. D. Greene,, J. G. Wells,, L. Hutwagner,, P. M. Griffin, and Escherichia coli 0157:H7 Study Group. 1997. Escherichia coli 0157:H7 diarrhea in the United States: clinical and epidemiologic features . Ann. Intern. Med. 126:505513.
48. Strockbine, N. A.,, L. R. M. Marques,, J. W. Newland,, H. W. Smith,, R. K. Holmes,, and A. D. O'Brien. 1986. Two toxin-converting phages from Escherichia coli 0157:H7 strain 933 encode antigenically distinct toxills with similar biologic activities. Infect. Immun. 53:135140.
49. Swerdlow, D. L.,, B. A. Woodruff,, R. C. Brady,, P. M. Griffin,, S. Tippen,, H. D. Donnell,, E. Geldreich,, B. J . Payne,, A. Meyer,, J. G. Wells,, K. D. Greene,, M. Bright,, N. H. Bean,, and P. A. Blake. 1992. A waterborne outbreak in Missouri of Escherichia coli 0157:H7 associated wilh bloody diarrhea and death. Ann. Intern. Med. 117:812819.
50. Tarr, P. I., and M. A. Neill. 1996. Perspective: The problem of non-0157 Shiga toxin (verocytotoxin)producing Escherichia coli. J. Infect. Dis. 174:11361139.
51. Tarr, P. I.,, M. A. Neill,, C. R. Clausen,, S. L. Watkins,, D. L. Christie,, and R. O. Hickman. 1990. Escherichia coli 0157:H7 and the hemolytic uremic syndrome: importance of early cultures in establishing the etiology. J. Infect. Dis. 162:553556.
52. Watanabe, H.,, A. Wada,, Y. Inagaki,, K. Itoh,, and K. Tamura. 1996. Outbreaks of enterohaemorrhagic Escherichia coli 0157:H7 infect ion by two different genotype strains in Japan, t 996. Lancet 348:831832.
53. Waters, J. R.,, J. C. M. Sharp,, and V. J. Dev. 1994. Infection caused by Escherichia coli 0157: H7 in Alberta. Canada, and in Scotland: a five•year review. 1987-1991. Clin. Infect. Dis. 19:834843.
54. Wells, J. G.,, B. R. Davis,, I. K. Wachsmuth,, L. W. Riley,, R. S. Remis,, R. Sokolow,, and G. K. Morris. 1983. Laboratory investigation of hemorrhagic cotitis outbreaks associated with a rare Escherichia coli serotype. J. Clin. Microbiol. 18:512520.

Tables

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Table 1.

Differential diagnosis of colitis caused by O157:H7

Citation: Griffin P, Boyce T. 1998. Escherichia coli O157:H7, p 137-146. In Scheld W, Armstrong D, Hughes J (ed), Emerging Infections 1. ASM Press, Washington, DC. doi: 10.1128/9781555816940.ch9

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