9 : Helicobacter Species other than Helicobacter pylori: Emerging Pathogens in Humans and Animals

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Many novel species are now known to play a role in naturally occurring gastrointestinal diseases in humans and several species of animals. This chapter provides an overview of the enterohepatic and gastric helicobacters (other than ) and their emerging role as important gastrointestinal pathogens with zoonotic potential. Enterohepatic helicobacters such as , and have been discussed in the chapter. , previously classified as (CLO-IA), was first isolated from the lower bowel of homosexual men with proctitis and colitis. In a retrospective study of 23 patients with -associated illness, 22 had the organism isolated from blood using an automated blood culture system where a slightly elevated growth index was noted. This study also described a new -associated syndrome, consisting of bacteremia and fever accompanied by leukocytosis and thrombocytopenia. Non- gastric helicobacters including and are discussed. The various spp. and their associated diseases in numerous hosts allow us the means to assess pathogenic mechanisms, as well as the utility of these in vivo models to develop various therapeutic and prophylactic strategies to eradicate or prevent -induced gastrointestinal disease in humans. The ultimate goal of these studies will be to eliminate afflictions causing significant human morbidity and mortality in both the developed and the developing worlds.

Citation: Fox J. 2000. Helicobacter Species other than Helicobacter pylori: Emerging Pathogens in Humans and Animals, p 121-135. In Scheld W, Craig W, Hughes J (ed), Emerging Infections 4. ASM Press, Washington, DC. doi: 10.1128/9781555816971.ch9
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Generic image for table
Table 1.

Nongastric species and their hosts (as of 1999)

Citation: Fox J. 2000. Helicobacter Species other than Helicobacter pylori: Emerging Pathogens in Humans and Animals, p 121-135. In Scheld W, Craig W, Hughes J (ed), Emerging Infections 4. ASM Press, Washington, DC. doi: 10.1128/9781555816971.ch9
Generic image for table
Table 2.

Characteristics that differentiate nongastric species

Citation: Fox J. 2000. Helicobacter Species other than Helicobacter pylori: Emerging Pathogens in Humans and Animals, p 121-135. In Scheld W, Craig W, Hughes J (ed), Emerging Infections 4. ASM Press, Washington, DC. doi: 10.1128/9781555816971.ch9

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