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12 : Amebiasis, an Emerging Disease

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Abstract:

Today, amebiasis is commonly found in nearly all tropical and subtropical countries. Improved diagnostic tests are beginning to overturn some of the commonly held beliefs about amebiasis. Amebiasis outbreaks in developed nations have resulted from contamination of water supplies with sewage secondary to inadequate water maintenance and treatment. Four glycolytic isoenzymes (glucosephosphate isomerase, phosphoglucomutase, hexokinase, and malic enzyme) exhibit different migration patterns on gel electrophoresis. The cytologic diagnosis of amebiasis is neither specific nor sensitive. and are identical in appearance. Since in most areas is more common than , this makes cytologic diagnosis extremely nonspecific. Detection of the Gal-GalNAc lectin antigen in serum can be used to identify infection. The application of riboprinting techniques may therefore provide a better understanding of the epidemiology of amebiasis, including different modes of transmission. One study investigated 105 cases of travelers returning from regions of endemicity and residents of those regions, with infection with and/or identified by microscopic detection. Twenty-one of 60 isolates were identified as by PCR and hexokinase isoenzyme, including isolates from 13 of 26 infected patients with amebiasis-like symptoms. The other important group to affect the epidemiology of amebiasis in the United States is the immigrant population, especially Hispanic and Pacific Islander immigrants and Indochinese refugees.

Citation: Tanyuksel M, Tachibana H, Petri W. 2001. Amebiasis, an Emerging Disease, p 197-212. In Scheld W, Craig W, Hughes J (ed), Emerging Infections 5. ASM Press, Washington, DC. doi: 10.1128/9781555816988.ch12

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Humoral Immune Response
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Complement Fixation Test
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Parasitic Diseases
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References

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1. Abd-Alla, M. D.,, T. F. H. G. Jackson,, V. Gathiram,, A. M. EI-Hawey,, and J. I. Ravdin. 1993. Differentiation of pathogenic Entamoeba histolytica infections from nonpathogenic infections by detection of galactose-inhibitable adherence protein antigen in sera and feces. J. Clin. Microbiol. 31:28452850.
2. Abd-Alla, M. D.,, T. F. H. G. Jackson,, and J. I. Ravdin. 1998. Serum IgM antibody response to the galactose-inhibitable adherence lectin of Entamoeba histolytica. Am. J. Trop. Med. Hyg. 59:431434.
3. Abd-Alla, M. D.,, T. F. H. G. Jackson,, S. Reddy,, and J. I. Ravdin. 2000. Diagnosis of invasive amebiasis by enzyme-linked immunosorbent assay of saliva to detect amebic lectin antigen and antilectin immunoglobulin G antibodies. J. Clin. Microbiol. 38:23442347.
4. Abd-Alla, M. D.,, A. A. Wahib,, and J. I. Ravdin. 2000. Comparison of antigen-capture ELISA to stool-culture methods for the detection of asymptomatic Entamoeba species infection in Kafer Daoud, Egypt. Am. J. Trop. Med. Hyg. 62:579582.
5. Abou-EI-Magd, I.,, C. G. Soong,, A. M. EI-Hawey,, and J. I. Ravdin. 1996. Humoral and mucosal IgA antibody response to a recombinant 52-kDa cysteine-rich portion of the Entamoeba histolytica galactose-inhibitable lectin correlates with detection of native 170-kDa lectin antigen in serum of patients with amebic colitis. J. Infect. Dis. 174:157162.
5.a. Ali, I. K. M.,, P. F. Ayeh-Kumi,, L. A. Lockhart,, W. A. Petri, Jr.,, and R. Haque. Entamoeba histolytica: genetic diversity of clinical isolates from Bangladesh as demonstrated by polymorphisms in the serine-rich gene. Exp. Parasitol., in press.
6. Anaya-Vebizquez, F.,, and A. Barrios-Conejo. 2000. Cytological and immunological methods to identify Entamoeba histolytica and Entamoeba dispar trophozoites in patients from Guanajuato, Mexico. Arch. Med. Res. 31:S32S33.
7. Braga, L. L.,, A. A. M. Lima,, C. L. Sears,, R. D. Newman,, T. Wuhib,, C. A. Paiva,, R. L. Guerrant,, and B. J. Mann. 1996. Seroepidemiology of Entamoeba histolytica in a slum in northeastern Brazil. Am. J. Trop. Med. Hyg. 55:693697.
8. Braga, L. L.,, Y. Mendonca,, C. A. Paiva,, A. Sales,, A. L. M. Cavalcante,, and B. J. Mann. 1998. Seropositivity for and intestinal colonization with Entamoeba histolytica and Entamoeba dispar in individuals in northeastern Brazil. J. Clin. Microbiol. 36:30443045.
9. Caballero-Salcedo, A.,, M. Viveros-Rogel,, B. Salvatierra,, R. Tapia-Conyer,, J. Sepulveda-Amor,, G. Gutierrez,, and L. Ortiz-Ortiz. 1994. Seroepidemiology of amebiasis in Mexico. Am. J. Trop. Med. Hyg. 50:412419.
10. Cheng, H. S.,, and L. C. Wang. 1999. Amoebiasis among institutionalized psychiatric patients in Taiwan. Epidemiol. Infect. 122:317322.
11. Clark, C. G.,, and L. S. Diamond. 1993. Entamoeba histolytica: a method for isolate identification. Exp. Parasitol. 77:450455.
12. Clark, C. G.,, and L. S. Diamond. 1997. Intraspecific variation and phylogenetic relationships in the genus Entamoeba as revealed by riboprinting. J. Eukaryot. Microbiol. 44:142154.
13. Clark, C. G.,, and L. S. Diamond. 1991. Ribosomal RNA genes of 'pathogenic' and 'nonpathogenic' Entamoeba histolytica are distinct. Mol. Biochem. Parasitol. 49:297302.
14. Diamond, L. S.,, and C. G. Clark. 1993. A redescription of Entamoeba histolytica Schaudinn, 1903 (emended Walker, 1911) separating it from Entamoeba dispar Brumpt, 1925. J. Eukaryot. Microbiol. 40:340344.
15. Doganci, L.,, M. Tanyuksel,, and H. Gun. 1997. Overdiagnosis of intestinal amoebosis in Turkey. Lancet 350:670.
16. Garfinkel, L. I.,, M. Giladi,, M. Huber,, C. Gitler,, D. Mirelman,, M. Revel,, and S. Rozenblatt. 1989. DNA probes specific for Entamoeba histolytica possessing pathogenic and nonpathogenic zymodemes. Infect. Immun. 57:926931.
17. Gathiram, V.,, and T. F. H. G. Jackson. 1985. Frequency distribution of Entamoeba histolytica zymodemes in a rural South African population. Lancet i:7l9721.
18. Gathiram, V.,, and T. F. H. G. Jackson. 1987. A longitudinal study of asymptomatic carriers of pathogenic zymodemes of Entamoeba histolytica. S. Afr. Med. J. 72:669672.
19. Gatti, S.,, C. Cevini,, L. Marchi,, S. Novati,, and M. Scaglia. 1995. Entamoeba histolytica autochthonous isolates from mentally retarded Italian patients. Parasitol. Res. 81:148151.
20. Ghosh, S.,, M. Frisardi,, L. Ramirez-Avila,, S. Descoteaux,, K. Sturm-Ramirez,, O. A. NewtonSanchez,, J. I. Santos-Preciado,, C. Ganguly,, A. Lohia,, S. Reed,, and J. Samuelson. 2000. Molecular epidemiology of Entamoeba spp.: evidence of a bottleneck (demographic sweep) and transcontinental spread of diploid parasites. J. Clin. Microbiol. 38:38153821.
21. Gonzalez, C. R.,, A. Isibasi,, V. Ortiz-Navarrete,, J. Paniagua,, J. A. Garcia,, A. Ramirez,, B. Salvatierra,, R. Tapia,, J. Sepulveda,, G. Gutierrez,, and J. Kumate. 1995. Prevalence of antibodies against Entamoeba histolytica in Mexico measured by ELISA. Epidemiol. Infect. 115:535543.
22. Gonzalez-Ruiz, A.,, and S. G. Wright. 1998. Disparate amoebae. Lancet 351:16721673.
23. Haque, R.,, I. K. M. Ali,, and W. A. Petri, Jr. 1999. Prevalence and irmnune response to Entamoeba histolytica infection in preschool children in Bangladesh. Am. J. Trop. Med. Hyg. 60:10311034.
24. Haque, R.,, A. S. G. Faruque,, P. Hahn,, D. M. Lyerly,, and W. A. Petri, Jr. 1997. Entamoeba histolytica and Entamoeba dispar infection in children in Bangladesh. J. Infect. Dis. 175:734736.
25. Haque, R.,, I. K. M. Ali,, and W. A. Petri, Jr. 2000. Salivary antilectin IgA antibodies in a cohort of children residing in an endemic area of Bangladesh. Arch. Med. Res. 31:S41S43.
26. Haque, R.,, N. U. Mollah,, I. K. M. Ali,, K. Alam,, A. Eubanks,, D. Lyerly,, and W. A. Petri, Jr. 2000. Diagnosis of amebic liver abscess and intestinal infection with the TechLab Entamoeba histolytica II antigen detection and antibody tests. J. Clin. Microbiol. 38:32353239.
27. Haque, R.,, L. M. Neville,, P. Hahn,, and W. A. Petri, Jr. 1995. Rapid diagnosis of Entamoeba infection by using Entamoeba and Entamoeba histolytica stool antigen detection kits. J. Clin. Microbiol. 33:25582561.
28. Healey, G. R. 1986. Irmnunologic tools in the diagnosis of amebiasis: epidemiology in the United States. Rev. Infect. Dis. 8:239246.
29. Huston, C. D.,, and W. A. Petri, Jr. 1999. Amebiasis: clinical implications of the recognition of Entamoeba dispar. Curr. Infect. Dis. Rep. 1:441447.
30. Huston, C. D.,, W. A. Petri, Jr.,, and R. Haque,. 2001. Amebiasis, p. 5054. In R. E. Rakel (ed.), Rakel and Bope: Conn's Current Therapy, 53rd ed. W. B. Saunders Company, Philadelphia, Pa.
31. Jackson, T.,, S. Reddy,, J. Fincham,, M. Abd-Alla,, S. Welles,, and J. I. Ravdin. 2000. A comparison of cross-sectional and longitudinal seroepidemiological assessments of Entamoeba-infected populations in South Africa. Arch. Med. Res. 31:S36S37.
32. Jackson, T. F. H. G., V, Gathiram, and A. E. Simjee. 1985. Seroepidemiological study of antibody responses to the zymodemes of Entamoeba histolytica. Lancet i:716719.
33. Kelsall, B. L.,, T. G. Jackson,, V. Gathiram,, S. B. Salig,, M. Vaithilingum,, R. D. Pearson,, and J. I. Ravdin. 1994. Secretory irmnunoglobulin A antibodies to the galactose-inhibitable adherence protein in the saliva of patients with amebic liver disease. Am. J. Trop. Med. Hyg. 51:454459.
34. Kobayashi, S.,, R. A. Fonseca,, C. M. Andrade,, V. M. de Melo,, H. Tachibana,, N. Kaneko,, S. Tateno,, and T. Takeuchi. 1993. Seroepidemiologic studies on amebiasis in Grand Recife, a possible endemic area of nonpathogenic Entamoeba histolytica. Permambuca. Brazil, Jpn. J. Parasitol. 42:484492.
35. Kobayashi, S.,, E. Okuzawa,, T. Takeuchi,, and H. Tachibana. 1992. Zymodeme profiles and reactivity to a monoclonal antibody specific for pathogenic Entamoeba histolytica of the isolates from serologically positive Japanese homosexual men with invasive amoebiasis. Jpn. Arch. Sex. Transm. Dis. 3:127130.
36. Kraoul, L.,, H. Adjmi,, V. Lavarde,, J. F. Pays,, C. Tourte-Schaefer,, and C. Hennequin. 1997. Evaluation of a rapid enzyme immunoassay for diagnosis of hepatic amoebiasis. J. Clin. Microbiol. 35:15301532.
37. Krogstad, D. J.,, H. C. Spencer, Jr.,, G. R. Healy,, N. N. Gleason,, D. J. Sexton,, and C. A. Herron. 1978. Amebiasis: epidemiologic studies in the United States, 1971-1974. Ann. Intern. Med. 88:8997.
38. Lotter, H.,, T. F. H. G. Jackson,, and E. Tannich. 1995. Evaluation of three serological tests for the detection of anti amebic antibodies applied to sera of patients from an area endemic for amebiasis. Trop. Med. Parasitol. 46:180182.
39. Mann, B. J.,, B. E. Torian,, T. S. Vedvick,, and W. A. Petri, Jr. 1991. Sequence of cysteine-rich galactose-specific lectin of Entamoeba histolytica. Proc. Natl. Acad. Sci. USA 88:32483252.
40. Mirelman, D.,, Y. Nuchamowitz,, and T. Stolarsky. 1997. Comparison of use of enzyme-linked immunosorbent assay-based kits and PCR amplification of rRNA genes for simultaneous detection of Entamoeba histolytica and E. dispar. J. Clin. Microbiol. 35:24052407.
41. Nagakura, K.,, H. Tachibana,, Y. Kaneda,, H. Suzuki,, K. Sasaoka,, S. Kobayashi,, and T. Takeuchi. 1990. Amebiasis in institutions for the mentally retarded in Kanagawa Prefecture, Japan. Jpn. J. Med. Sci. Biol. 43:123131.
42. Nagakura, K.,, H. Tachibana,, T. Tanaka,, Y. Kaneda,, M. Tokunaga,, M. Sasao,, and T. Takeuchi. 1989. An outbreak: of amebiasis in an institution for the mentally retarded in Japan. Jpn. J. Med. Sci. Biol. 42:6376.
43. Novati, S.,, M. Sironi,, S. Granata,, A. Bruno,, S. Gatti,, M. Scaglia,, and C. Bandi. 1996. Direct sequencing of the PCR amplified SSU rRNA gene of Entamoeba dispar and the design of primers for rapid differentiation from Entamoeba histolytica. Parasitol. 112:363369.
44. Nozaki, T.,, I. Aca,, E. Okuzawa,, M. Magalhaes,, S. Tateno,, and T. Takeuchi. 1990. Zymodemes of Entamoeba histolytica isolated in the Amazon and the north-east of Brazil. Trans. R. Soc. Trop. Med. Hyg. 84:387388.
45. Nozaki, T.,, S. R. Motta,, T. Takeuchi,, S. Kobayashi,, and P. G. Sargeaunt. 1989. Pathogenic zymodemes of Entamoeba histolytica in Japanese male homosexual population. Trans. R. Soc. Trop. Med. Hyg. 83:525.
46. Ohnishi, K.,, and M. Murata. 1997. Present characteristics of symptomatic amebiasis due to Entamoeba histolytica in the east-southeast area of Tokyo. Epidemiol. Infect. 119:363367.
47. Ohnishi, K.,, M. Murata,, H. Kojima,, N. Takemura,, T. Tsuchida,, and H. Tachibana. 1994. Brain abscess due to infection with Entamoeba histolytica. Am. J. Trop. Med. Hyg. 51:180182.
48. Petri, W. A., Jr.,, R. Haque,, D. Lyerly,, and R. R. Vines. 2000. Estimating the impact of amebiasis on health. Parasitol. Today 16:320321.
49. Petri, W. A., Jr.,, T. F. Jackson,, V. Gathiram,, K. Kress,, L. D. Saffer,, T. L. Snodgrass,, M. D. Chapman,, Z. Keren,, and D. Mirelman. 1990. Pathogenic and nonpathogenic strains of Entamoeba histolytica can be differentiated by monoclonal antibodies to the galactose-specific adherence lectin. Infect. Immun. 58:18021806.
50. Pillai, D. R.,, J. S. Keystone,, D. C. Sheppard,, J. D. MacLean,, D. W. MacPherson,, and K. C. Kain. 1999. Entamoeba histolytica and Entamoeba dispar: epidemiology and comparison of diagnostic methods in a setting of nonendemicity. Clin. Infect. Dis. 29:13151318.
51. Proctor, E. M.,, Q. Wong,, J. Yang,, and J. S. Keystone. 1987. The electrophoretic isoenzyme patterns of strains of Entamoeba histolytica isolated in two major cities in Canada. Am. J. Trop. Med. Hyg. 37:296301.
52. Rivera, W. L.,, and H. Kanbara. 1999. Detection of Entamoeba dispar DNA in macaque feces by polymerase chain reaction. Parasitol. Res. 85:493495.
53. Rivera, W. L.,, H. Tachibana,, and H. Kanbara. 1998. Field study on the distribution of Entamoeba histolytica and Entamoeba dispar in the northern Philippines as detected by the polymerase chain reaction. Am. J. Trop. Med. Hyg. 59:916921.
54. Rivera, W. L.,, H. Tachibana,, M. R. A. Silva-Tahat,, H. Uemura,, and H. Kanbara. 1996. Differentiation of Entamoeba histolytica and E. dispar DNA from cysts present in stool specimens by polymerase chain reaction: its field application in the Philippines. Parasitol. Res. 82:585589.
55. Roche, J.,, and A. Benito. 1999. Prevalence of intestinal parasite infections with special reference to Entamoeba histolytica on the island of Bioko (Equatorial Guinea). Am. J. Trop. Med. Hyg. 60:257262.
56. Sanchez-Gnillen, M. C.,, M. Velazquez-Rojas,, H. Salgado-Rosas,, E. Torres-Rasgado,, R. PerezFuentes,, J. Martinez-Munguia,, and P. Talamas-Rohana. 2000. Seroprevalence of anti-Entamoeba histolytica antibodies by IHA and ELISA assays in blood donors from Puebla, Mexico, Arch. Med. Res. 31:S53S54.
57. Sargeaunt, P. G.,, J. E. Williams,, T. F. H. G. Jackson,, and A. E. Simjee. 1982. A zymodeme study of Entamoeba histolytica in a group of South African schoolchildren. Trans. R. Soc. Trop. Med. Hyg. 76:401402.
58. Sehgal, D.,, V. Mittai,, S. Ramachandran,, S. K. Dhar,, A. Bhattacharya,, and S. Bhattacharya. 1994. Nucleotide sequence organization and analysis of the nuclear ribosomal DNA circle of the protozoan parasite Entamoeba histolytica. Mol. Biochem. Parasitol. 67:205214.
59. Stanley, S. L.,, T. F. H. G. Jackson,, J. Foster,, and S. Singh. 1998. Longitudinal study of the antibody response to recombinant Entamoeba histolytica antigens in patients with amebic liver abscess. Am. J. Trop. Med. Hyg. 58:414416.
60. Tachibana, H.,, X. J. Cheng,, S. Kobayashi,, N. Matsubayashi,, S. Gotoh,, and K. Matsubayashi. 2001. High prevalence of infection with Entamoeba dispar, but not E. histolytica, in captive macaques. Parasitol. Res. 87:1417.
61. Tachibana, H.,, S. Ihara,, S. Kobayashi,, Y. Kaneda,, T. Takeuchi,, and Y. Watanabe. 1991. Differences in genomic DNA sequences between pathogenic and nonpathogenic isolates of Entamoeba histolytica identified by polymerase chain reaction. J. Clin. Microbiol. 29:22342239.
62. Tachibana, H.,, S. Kobayashi,, Y. Kato,, K. Nagakura,, Y. Kaneda,, and T. Takeuchi. 1990. Identification of a pathogenic isolate-specific 30,000-M, antigen of Entamoeba histolytica by using a monoclonal antibody. Infect. Immun. 58:955960.
63. Tachibana, H.,, S. Kobayashi,, K. Nagakura,, Y. Kaneda,, and T. Takeuchi. 2000. Asymptomatic cyst passers of Entamoeba histolytica but not Entamoeba dispar in institutions for the mentally retarded in Japan. Parasitol. Int. 49:3135.
64. Tachibana, H.,, S. Kobayashi,, E. Okuzawa,, and G. Masuda. 1992. Detection of pathogenic Entamoeba histolytica DNA in liver abscess fluid by polymerase chain reaction. Int. J. Parasitol. 22:11931196.
65. Tachibana, H.,, S. Kobayashi,, K. C. Paz,, I. S. Aca,, S. Tateno,, and S. Ihara. 1992. Analysis of pathogenicity by restriction-endonuclease digestion of amplified genomic DNA of Entamoeba histolytica isolated in Pernambuco, Brazil. Parasitol. Res. 78:433436.
66. Tannich, E.,, R. D. Horstmann,, J. Knobloch,, and H. H. Arnold. 1989. Genomic DNA differences between pathogenic and nonpathogenic Entamoeba histolytica. Proc. Natl. Acad. Sci. USA 86:51185122.
67. Walderich, B.,, A. Weber,, and J. Knobloch. 1997. Differentiation of Entamoeba histolytica and Entamoeba dispar from German travelers and residents of endemic areas. Am. J. Trop. Med. Hyg. 57:7074.
68. Walsh, J. A. 1986. Problems in recognition and diagnosis of amebiasis: estimation of the global magnitude of morbidity and mortality. Rev. Infect. Dis. 8:228238.
69. Weinke, T.,, B. Friedrich-Janicke,, P. Hopp,, and K. Janitschke. 1989. Prevalence and clinical importance of Entamoeba histolytica in two high-risk groups: travelers returning from the tropics and male homosexuals. J. Infect. Dis. 161:10291031.
70.World Health Organization. 1997. Amoebiasis. Wkly. Epidemiol. Rec. 72:9799.
71. Zengzhu, G.,, R. Bracha,, Y. Nuchamowitz,, W. Cheng-I,, and D. Mirelman. 1999. Analysis by enzyme-linked immunosorbent assay and PCR of human liver abscess aspirates from patients in China for Entamoeba histolytica. J. Clin. Microbiol. 37:30343036.

Tables

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Table 1

Sensitivity and specificity of tests of diagnosis for amebiasis in patients with colitis and liver abscess

Citation: Tanyuksel M, Tachibana H, Petri W. 2001. Amebiasis, an Emerging Disease, p 197-212. In Scheld W, Craig W, Hughes J (ed), Emerging Infections 5. ASM Press, Washington, DC. doi: 10.1128/9781555816988.ch12

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