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Oral Microbial Communities: Genomic Inquiry and Interspecies Communication

Editor: Paul E. Kolenbrander1
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Affiliations: 1: Oral Infection and Immunity Branch, National Institute of Dental, Craniofacial Research, National Institutes of Health, Bethesda, MD 20892
Content Type: Monograph
Format: Electronic, Hardcover
Publication Year: 2011

Category: Genomics and Bioinformatics

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Oral bacteria are the first human microbiome to encounter the food we eat. To date, most research has focused on the role of oral bacteria in the development and progression of caries and periodontal disease; however, little is known about the microbial communities that maintain a healthy oral cavity. This book, , helps readers understand how multispecies microbial communities function to maintain and promote oral health as well as disease. It explores the immense opportunities presented by readily accessible, genetically tractable, genome-sequenced oral species that naturally form multispecies communities.

Emphasizing the use of genomic inquiry to probe questions, examines multispecies community interactions, spatiotemporal organization, and gene function. Readers will find coverage of all the major microbe species currently under investigation by leading oral microbiologists. In particular, the book highlights model systems that study oral bacterial interactions, including biofilm growth using saliva as the source of nutrition.

The book’s 25 chapters have been contributed by an international team of leading oral microbiologists. As a result, readers will gain a deeper understanding of the role of the oral microbiome in health, oral disease, and systemic disease. Moreover, they will gain a new appreciation of how oral microbial communities form, evolve, and communicate the intricacies of multispecies community life.

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Microbiology Today

11 June 2013

This book presents the latest information obtained at the molecular level on oral microbial communities, with particular reference to dental plaque biofilms. It emphasizes how recent advances in sequencing and associated bioinformatics are enabling a detailed analysis of the role of the oral microbiota in health and disease. The book examines how genomic inquiry can be applied to some of the key commensal and pathogenic species involved in early to late phases of dental plaque development. Although the precise biological mechanisms involved in communication and other interactions between species, and with the host, are still being determined, the latest strategies being applied to these areas of research are described.

With excellent contributions from 58 experts from around the globe this book will be a valuable and timely resource.

Society for General Microbiology - Microbiology Today

Reviewer: Rob Allaker, Queen Mary University of London

Review Date: May 2012

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