Tuberculosis and Nontuberculous Mycobacterial Infections, Sixth Edition

Editor: David Schlossberg1
Affiliations: 1: Professor of Medicine Temple University School of Medicine and Medical Director Tuberculosis Control Program Philadelphia Department of Public Health Philadelphia, Pennsylvania
Content Type: Monograph
Format: Hardcover, Electronic
Publication Year: 2011

Category: Clinical Microbiology; Bacterial Pathogenesis

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One-third of the world’s human population is currently infected with tuberculosis. Tuberculosis remains epidemic, causing close to two million deaths each year. Most of these deaths occur in developing nations; however, developed nations also struggle with tuberculosis, contending with such growing challenges as drug resistance, immigration, immunosuppression, and nontuberculous mycobacterial infection. Nearly 30 years after the publication of the first edition, the Sixth Edition of this comprehensive reference gathers the most current science and tools available in the fight against tuberculosis, enabling readers to fully understand the underlying mechanisms of tuberculosis and correctly diagnose and manage the disease.

is divided into three sections. Section I presents basic concepts of epidemiology, pathophysiology, diagnosis, medical and surgical therapy, drug-resistant tuberculosis, vaccines, and tuberculosis in enclosed populations. Section II covers both classic and more recent clinical manifestations of tuberculosis infection. Separate chapters address every organ system as well as issues unique to pregnancy, infants and children, HIV infection, organ transplantation and immune reconstitution inflammatory syndrome. Section III explores nontuberculous mycobacterial infections, including a detailed discussion of the clinical syndromes produced by these organisms.

All the chapters have been written by leading experts whose experience ranges from basic and clinical research to bedside medicine.

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Doody Enterprises

17 August 2013


This is a complete and user‐friendly review of tuberculosis and nontuberculous mycobacterial infections. The previous edition was published in 2006.


With the multiple issues in the management of tuberculosis, especially with the emergence of antimicrobial resistance and the discovery of new nontuberculous mycobacterial infections, just to name a few of the challenges faced by clinical practitioners, a book like this is needed.


According to the authors, the book is designed to be helpful to clinicians, epidemiologists, and scientists involved in the diagnosis and treatment of tuberculosis. The book will be more appealing to clinicians than scientists, who might be more interested in books that provide more robust information on molecular biology and pathogenesis of tuberculosis (e.g., the three volumes of the Handbook of Tuberculosis, Kaufmann et al. (Wiley, 2008)). The authors are leaders in tuberculosis, and primarily based in the U.S. I wish the authorship was more global.


The book is divided into three sections that cover general considerations, clinical syndromes, and nontuberculous mycobacteria. The first section is very diverse, providing information on multiple aspects of the management of tuberculosis, including epidemiology, pathophysiology, and treatment. The book follows a style that will be familiar to readers of books published by the American Society of Microbiology. It is a shame that it does not have any sort of color illustrations ‐‐ not even a color photograph of a positive stain for acid fast bacilli.


This is a well‐rounded book on tuberculosis, which strives to be helpful to a diverse group of readers, but will be most beneficial to clinicians. It faces competition from other books on tuberculosis, and it is hard to see how it differentiates itself.

Weighted Numerical Score: 79 ‐ 3 Stars

Doody Enterprises

Reviewer: Carlos E Figueroa Castro, MD (Boone Hospital Center)

Review Date: May 2012

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