1887

and Candidiasis, Second Edition

Editors: Richard A. Calderone1, Cornelius J. Clancy2
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Affiliations: 1: Georgetown University Medical Center, Washington, DC; 2: Department of Medicine, Infectious Diseases Division, University of Pittsburgh, Pittsburgh, PA
Content Type: Monograph
Format: Hardcover, Electronic
Publication Year: 2012

Category: Fungi and Fungal Pathogenesis; Clinical Microbiology

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The underlying mechanisms of and candidiasis and promising new directions in drug discovery and treatment.

  • Reviews all aspects of this common fungal pathogen and its impact on human health, from the basic biology of to the clinical management of candidiasis.
  • Reviews the latest basic and clinical research, focusing on findings in genome variability, host-pathogen interactions, antifungal resistance and drug discovery, and diagnostics to foster better understanding and treatment of candidiasis.
  • Examines recent discoveries that have shed light on morphogenesis and the cell cycle, including how new findings on host responses may have applications for the diagnosis of blood-borne candidiasis.

Recommended for researchers and clinicians in medical mycology, medical microbiology, and infectious disease.

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Microbiology Today

03 March 2013

This new&#160;[edition]&#160;is not merely an updated replacement of the first edition. In fact, it is more like a second volume and reviews the huge scientific advances in Candida species, immunity and disease that have occurred in the 10 years since the publication of the first edition. Each of the chapters is a well-written and thought-provoking review of one aspect of Candida biology and/or immunity and disease associated with these species, written by experts in that area of research. Whilst the first edition had a strong focus on the fungus, this edition more directly relates Candida biology to clinical disease and therapy. Unique to this edition is the 'Cool tools' section, which highlights recently developed experimental techniques and approaches to increase our understanding of Candida species and virulence now that the genome sequences are available for many Candida species.

This edition will be essential reading for all researchers and clinicians with an interest in Candida and represents excellent value for money. However, the second edition should sit alongside the first, as the first edition still contains information, such as clinical identification of Candida species, no longer covered in this newer edition.

Society for General Microbiology: Microbiology Today

Reviewer: Donna MacCallum, University of Aberdeen

Review Date: 2011

Doody Enterprises

02 January 2013

Description



This is an update of a comprehensive reference on the current state of knowledge and research on this important fungal pathogen. It encompasses everything from recent discoveries in traditional research areas such as morphology and growth to the emerging public health threat of candidiasis. The previous edition was published in 2002.

Purpose



The book collects the most current information in the field of Candida biology in a single reference and includes sections on genomic variability, host-pathogen interaction and immunology, vaccine candidates, therapeutic management including resistance mechanisms, and new drug discovery.

Audience



It is targeted at researchers and physicians with experience in the field of fungal pathogens; especially those in infectious disease, microbiology, and medical mycology. The editors and contributing authors are highly respected authorities on the subject.

Features



This detailed and thorough book includes concise chapters that are extensively referenced and sufficiently illustrated. It includes sections on Candida biology and genomics, host-pathogen interactions, and specific human immunological responses, as well as clinical issues and current research surrounding diagnostics and therapeutics. The references are current and conveniently listed at the end of each chapter. A small section of full-color illustrations is placed between sections I and II, with black-and-white illustrations and figures throughout the remainder of the book. The book seamlessly crosses disciplines and interweaves basic science and clinical concepts to provide a comprehensive knowledge base.

Assessment



This is a valuable compendium of scientific knowledge for readers who desire extensive detail on the state of the art of basic and clinical sciences in the field of Candida and candidiasis. It provides an exemplary framework upon which to build future research questions and provoke scientific inquiry.

Doody Enterprises

Reviewer: Kari A Simonsen, MD (University of Nebraska Medical Center)

Review Date: March 2012

©Doody’s Review Service

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