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Chapter 5 : Automation and Design of the Clinical Microbiology Laboratory

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Abstract:

This chapter discusses laboratory design and the growing impact of laboratory automation. The chapter is divided into two sections. The first section addresses more traditional considerations of laboratory design such as staffing, workflow, laboratory location, and the role of efficiency programs such as lean and Six Sigma. The second section discusses currently available systems for automating the clinical microbiology laboratory. Individual technologies for specimen processing, organism identification, and susceptibility testing as well as total lab automation are covered. Important considerations for purchase and utilization are outlined to aid readers in deciding which technology is right for their lab and how best to approach implementation.

Citation: Doern C, Holfelder M. 2015. Automation and Design of the Clinical Microbiology Laboratory, p 44-53. In Jorgensen J, Pfaller M, Carroll K, Funke G, Landry M, Richter S, Warnock D (ed), Manual of Clinical Microbiology, Eleventh Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817381.ch5
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FIGURE 1

InoqulA magnetic bead. doi:10.1128/9781555817381.ch5.f1

Citation: Doern C, Holfelder M. 2015. Automation and Design of the Clinical Microbiology Laboratory, p 44-53. In Jorgensen J, Pfaller M, Carroll K, Funke G, Landry M, Richter S, Warnock D (ed), Manual of Clinical Microbiology, Eleventh Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817381.ch5
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FIGURE 2

PREVI Isola-inoculated agar plate. doi:10.1128/9781555817381.ch5.f2

Citation: Doern C, Holfelder M. 2015. Automation and Design of the Clinical Microbiology Laboratory, p 44-53. In Jorgensen J, Pfaller M, Carroll K, Funke G, Landry M, Richter S, Warnock D (ed), Manual of Clinical Microbiology, Eleventh Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817381.ch5
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Image of FIGURE 3
FIGURE 3

BD-Kiestra TLA with barcoding, inoculation (InoqulA) (depth, 93.5 cm; width, 417.2 cm; weight, 770 kg), and incubation (ReadA) (depth, 164.0 cm; width, 87 cm; weight, 430–730 kg). doi:10.1128/9781555817381.ch5.f3

Citation: Doern C, Holfelder M. 2015. Automation and Design of the Clinical Microbiology Laboratory, p 44-53. In Jorgensen J, Pfaller M, Carroll K, Funke G, Landry M, Richter S, Warnock D (ed), Manual of Clinical Microbiology, Eleventh Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817381.ch5
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Image of FIGURE 4
FIGURE 4

FMLA, bioMérieux, smart incubation unit (depth, 145.7 cm; width, 128.0 cm; weight, 850 to 950 kg); PREVI Isola (depth, 90.7 cm; width, 144.5 cm; weight, 298 kg). doi:10.1128/9781555817381.ch5.f4

Citation: Doern C, Holfelder M. 2015. Automation and Design of the Clinical Microbiology Laboratory, p 44-53. In Jorgensen J, Pfaller M, Carroll K, Funke G, Landry M, Richter S, Warnock D (ed), Manual of Clinical Microbiology, Eleventh Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817381.ch5
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Image of FIGURE 5
FIGURE 5

WASPLab, Copan: WASP (depth, 119.1 cm; width, 194.9 cm; weight, 700 kg); double incubator (depth, 83.0 cm; width, 174.0 cm; weight, 700 kg); imaging system (depth, 121.3 cm; width, 37.5 cm; weight, 250 kg). doi:10.1128/9781555817381.ch5.f5

Citation: Doern C, Holfelder M. 2015. Automation and Design of the Clinical Microbiology Laboratory, p 44-53. In Jorgensen J, Pfaller M, Carroll K, Funke G, Landry M, Richter S, Warnock D (ed), Manual of Clinical Microbiology, Eleventh Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817381.ch5
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References

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Tables

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TABLE 1

Automated inoculation systems

Citation: Doern C, Holfelder M. 2015. Automation and Design of the Clinical Microbiology Laboratory, p 44-53. In Jorgensen J, Pfaller M, Carroll K, Funke G, Landry M, Richter S, Warnock D (ed), Manual of Clinical Microbiology, Eleventh Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817381.ch5

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