Chapter 15.1 : Introduction

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Laboratory workers are at high risk for occupational exposure to infectious agents. Infections can be acquired from exposure to contaminated blood, tissue, and other material. The greatest risks for clinical microbiologists are associated with the processing of specimens and the manipulating of pathogens isolated from these materials. The actual incidence of laboratory-acquired infections is probably higher than recognized due to subclinical symptoms and poor compliance in reporting.

Citation: Garcia L. 2010. Introduction, p 648-648. In Clinical Microbiology Procedures Handbook, 3rd Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817435.ch15.1
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1. Centers for Disease Control andPrevention. 1994. Guidelines for preventing the transmission of Mycobacterium tuberculosis in health-care facilities. MMWRMorb. Mortal. Wkly. Rep. 43:1128.
2. Centers for Disease Control andPrevention and National Institutes of Health. February 2007, posting date. BioSafety in Microbiological and BiomedicalLaboratories, 5th ed. U.S. GovernmentPrinting Office, Washington, DC. http://www.cdc.gov/OD/ohs/biosfty/bmbl5/bmbl5toc.htm.
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5. Noble, M. A., 2007. Prevention andcontrol of laboratory- acquired infections, p. 97106. In P. R. Murray,, E. J. Baron,, J. H. Jorgensen,, M. L. Landry,, and M. A. Pfaller (ed.), Manual of Clinical Microbiology, 9th ed. ASM Press, Washington, DC.
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7. Occupational Safety and HealthAdministration. 1997. Occupational exposure to tuberculosis:proposed rule. Fed. Regist. 62:5416054308.
8. Sewell, D. L. 2006. Laboratory-acquired infections: are microbiologists at risk? Clin. Microbiol. Newsl. 28:17.
9. Sewell, D. L., 2004. Nosocomialinfections in diagnostic laboratories, p. 14311441. In C. G. Mayall (ed.), Hospital Epidemiology and Infection Control, 3rd. ed. Lippincott Williams & Wilkins, Philadelphia, PA.
10. Sewell, D. L. 1996. Laboratories at risk: the threat of exposure to infectious agents, and the role of the biosafety program. Lab. Med. 27:673678.
11. Sewell, D. L. 1995. Laboratory-associated infections and biosafety. Clin. Microbiol. Rev. 8:389- 405

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