Chapter 16.8 : Tularemia—

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is a tiny (0.2- to 0.5- by 0.7- to 1.0-μm), pleomorphic, nonmotile, fastidious, gram-negative, facultative intracellular coccobacillus. can be divided into two subspecies, subsp. (type A) and subsp. (type B), based on virulence testing, 16S sequencing, biochemical reactions, and epidemiological features. Type A and type B strains are highly infectious (e.g., require only 50 to 100 organisms to cause disease) and are the principal agents of tularemia, a zoonotic plague-like disease distributed only in the northern hemisphere ( ). In the United States, the principal reservoir is the cottontail rabbit (lagomorph), but the disease may also be carried and transmitted by a variety of terrestrial and aquatic mammals, such as beavers, ground squirrels, muskrats, and other rodents ( ). Transmission to humans can occur through the handling of infected animals; through the bites of ticks, mosquitoes, or deerfly vectors; or by ingestion of contaminated stream water. subsp. is infrequently identified as a cause of human disease.

Citation: Garcia L. 2010. Tularemia—, p 779-782. In Clinical Microbiology Procedures Handbook, 3rd Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817435.ch16.8
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Image of Figure 16.8-1
Figure 16.8-1

sentinel-level laboratory flowchart.

Citation: Garcia L. 2010. Tularemia—, p 779-782. In Clinical Microbiology Procedures Handbook, 3rd Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817435.ch16.8
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