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Chapter 20 : Conjugative Transfer of Antibiotic Resistance in Escherichia coli
This chapter talks about the procedure for conjugative transfer of antibiotic resistance in Escherichia coli. Public health officials are quite concerned about the rise in antibiotic resistance among disease-causing organisms. For example, Campylobacter is a bacterium that causes stomach cramps, diarrhea, and fever. In 1992, 1.3% of cases of Campylobacter infection studied in Minnesota were caused by bacteria resistant to a fairly new class of antibiotics called quinolones (ciprofloxacin [Cipro] is an example of a quinolone). Virtually every clinically important antibiotic resistance gene is carried on a plasmid. Conjugation allows the spread of plasmids, not only between different individuals of the same bacterial species, but also between species and even between genera. Conjugation has been observed to occur in the soil; on plant surfaces; in lakes, rivers, oceans, sediments, and sewage treatment plants; and inside plants, insects, chickens, mice, and humans. It is believed that conjugation is the most important route of transmission of antibiotic resistance in most disease-causing bacteria. The spread of antibiotic resistance is included at the end of the chapter.
Key Concept Ranking
- Bacterial Cell Wall