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Chapter 23 : An Adventure in Dog Hair, Part I

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An Adventure in Dog Hair, Part I, Page 1 of 2

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Abstract:

This chapter talks about an adventure in dog hair color. It uses the scientific terminology to describe the pigments and the cells that produce them. Pigmentation in dogs and other mammals is caused by the relative amounts and types of two classes of pigment: eumelanin and phaeomelanin. The eumelanins are the black and brown pigments, while the phaeomelanins are red and yellow. Both eumelanins and phaeomelanins are synthesized in pigment-producing cells called melanocytes. A schematic of the synthesis pathways is shown in the chapter. First, the enzyme tyrosinase converts the amino acid tyrosine into a chemical called dopa-quinone. The enzyme called tyrosinase-related protein 2 (TYRP2) is present, it converts the dopaquinone into a version of eumelanin that has a brown color—Cocoa’s pigment. If the enzyme called tyrosinase-related protein 1 (TYRP1) is present, it converts the brown version of eumelanin into the final, black-colored pigment. It talks about two useful terms: genotype and phenotype.

Citation: Kreuzer H, Massey A. 2008. An Adventure in Dog Hair, Part I, p 242-245. In Molecular Biology and Biotechnology: A Guide for Students, Third Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817480_ch23

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Figures

Image of Figure 23.1
Figure 23.1

Synthesis of black and brown pigments (eumelanins) in melanocytes. First, tyrosinase converts tyrosine to dopaquinone. Next, TYRP2 converts dopaquinone to brown pigment. Finally, TYRP1 converts the brown pigment into black pigment.

Citation: Kreuzer H, Massey A. 2008. An Adventure in Dog Hair, Part I, p 242-245. In Molecular Biology and Biotechnology: A Guide for Students, Third Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817480_ch23
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Image of Figure 23.2
Figure 23.2

Pigment synthesis in Cocoa's melanocytes. First, tyrosinase converts tyrosine to dopaquinone. Next, TYRP2 converts dopaquinone to brown pigment. There is no TYRP1 to convert the brown pigment into black pigment. What effect does this lack of TYRP1 have on Cocoa's coloration?

Citation: Kreuzer H, Massey A. 2008. An Adventure in Dog Hair, Part I, p 242-245. In Molecular Biology and Biotechnology: A Guide for Students, Third Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817480_ch23
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Image of Figure 23.3
Figure 23.3

Pigment biosynthesis in the geneflower. Enzyme X converts a colorless precursor into a blue pigment. Next, enzyme Y converts the blue pigment into a purple pigment.

Citation: Kreuzer H, Massey A. 2008. An Adventure in Dog Hair, Part I, p 242-245. In Molecular Biology and Biotechnology: A Guide for Students, Third Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817480_ch23
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Image of Figure 23.4
Figure 23.4

Pigment biosynthesis in the roundbud. Enzyme Q converts a white precursor into a red pigment.

Citation: Kreuzer H, Massey A. 2008. An Adventure in Dog Hair, Part I, p 242-245. In Molecular Biology and Biotechnology: A Guide for Students, Third Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817480_ch23
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Download as Powerpoint

References

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