Chapter 8 : Distinguishing Pathovars from Nonpathovars:

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One defining feature of a pathovar is that, in a human host, it colonizes the same nonsterile ecologic niche in which nonpathovars establish themselves as commensals. This chapter talks about a bacterial organism, , that colonizes the oro- and naso-pharynx of the human host in similar proportions worldwide. The major current epidemiologic concerns regarding pneumococcal infections include the determinants of the emergence and spread in the community of drug-resistant strains of the pneumococcus and the relationship between asymptomatic carriage and disease. The latter addresses the issue of whether or not any strain that asymptomatically colonizes a host is also capable of causing invasive disease. Molecular epidemiologic approaches to these issues are discussed.

Citation: Riley L. 2004. Distinguishing Pathovars from Nonpathovars: , p 209-227. In Molecular Epidemiology of Infectious Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555817688.ch8

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Table 8.1

International pneumococcal clones recognized to have contributed to the increase in antimicrobial resistance worldwide

Adapted from reference .

ATCC, American Type Culture Collection.

Citation: Riley L. 2004. Distinguishing Pathovars from Nonpathovars: , p 209-227. In Molecular Epidemiology of Infectious Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555817688.ch8

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