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Chapter 28 : Mother Nature and the Design of a Regulatory Enzyme

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Abstract:

The author thinks his first meeting with Jacques Monod was in the mid-1950s, probably after Jim Watson, and he had put forward the DNA structure. He clearly recalls giving a seminar at the Pasteur Institute in which he suggested the quite erroneous theory that during protein synthesis the inducer was needed to fold up the enzyme correctly. Monod was an excellent sailor who could manage his 37-foot sloop by himself, whereas he was always a rather bumbling amateur. One year there was a scientific meeting at Naples. This chapter discusses the author`s most rewarding sailing experience with Jacques. Jacques was very companionable—one always enjoyed an evening when he was there—and it’s not everyone that one can go sailing with. Their general attitude to most scientific matters was very similar, yet their backgrounds were sufficiently different to make both of them eager to hear what the other thought. As each new thing comes up, one regrets so much not being able to talk it over with Jacques. Jacques would understand so quickly; he would appreciate the importance of the point; he would say something illuminating that hadn’t occurred to one; one could reach agreement together and a deeper understanding. It is for this reason that the author finds that he has no stomach for writing a book about Jacques` work even though the author still feels a small nagging sense of duty.

Citation: Buc H. 2003. Mother Nature and the Design of a Regulatory Enzyme, p 255-262. In Ullmann A (ed), Origins of Molecular Biology. ASM Press, Washington, DC. doi: 10.1128/9781555817763.ch28

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In New York, January 1973.

Citation: Buc H. 2003. Mother Nature and the Design of a Regulatory Enzyme, p 255-262. In Ullmann A (ed), Origins of Molecular Biology. ASM Press, Washington, DC. doi: 10.1128/9781555817763.ch28
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Citation: Buc H. 2003. Mother Nature and the Design of a Regulatory Enzyme, p 255-262. In Ullmann A (ed), Origins of Molecular Biology. ASM Press, Washington, DC. doi: 10.1128/9781555817763.ch28
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