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Bacteria versus Antibacterial Agents: an Integrated Approach

Author: Oreste A. Mascaretti1
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Affiliations: 1: Department of Organic Chemistry, Faculty of Biochemistry and Pharmacy, Universidad Nacional de Rosario, Rosario, Argentina
Content Type: Textbook
Format: Hardcover
Publication Year: 2003

Category: Bacterial Pathogenesis

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Designed as an introductory text on antibacterial agents, this new volume provides a clear, comprehensive and concise overview of the subject, including the most recent and significant developments in antibacterial agents with novel modes of action.

The basics of bacterial structure and function are reviewed, describing the basis for understanding mechanisms of antibacterial action, as well as the mechanisms developed by bacteria to overcome the action of antibacterial agents. The volume also covers the characteristic features of bacterial pathogenicity, the genetic basis of resistance to antibacterial drugs, the biochemical mechanisms of action of antibacterial drugs, how antibacterial drugs reach their targets in gram-positive and gram-negative bacteria, and the wide range of human immune responses against bacterial infections.

Recent advances in research and development of new classes of antibacterial drugs are examined, as are improved analogs of penicillin, cephalosporins, carbapenems, aminoglyosides, tetracyclines, etc.

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