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Chapter 10 : Pathogens of Swine

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Abstract:

The domestic pig () has assumed a significant role in biomedical research. The pig serves as an animal model for research involving the dermal, cardiopulmonary, gastrointestinal, renal, and other body systems. Swine have become the organ donor of choice in xenotransplantation experiments. In this regard, porcine reproductive and respiratory syndrome virus (PRRSV) is often found as a copathogen, along with , , porcine circovirus type 2, swine influenza virus, and other pathogens. Swine influenza virus (SIV) is a single-stranded RNA (ssRNA) virus in the family . SIV is one of the most studied of swine viral pathogens. More severe clinical signs accompany concurrent infection with pathogens such as , , , type 2, , and PRRSV. Clinical disease may accompany primary viral infection, such as swine influenza virus, pseudorabies virus, or PRRSV; or primary bacterial infection, as with . Among the most important in swine are spp.: , , , , , and . Pigs may be infected with a number of spp.; among these are , , , , , , and . In the lungs, larval migration results in verminous pneumonia, characterized by focal hemorrhaging, edema, emphysema, and secondary bacterial infections.

Citation: Baker D. 2003. Pathogens of Swine, p 281-339. In Natural Pathogens of Laboratory Animals. ASM Press, Washington, DC. doi: 10.1128/9781555817824.ch10
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