11 The Arboviruses

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On a global scale, the public health danger posed by the arboviruses is massive. Probably no area in virology is as daunting for the practicing clinician as are the arboviruses. Much of the problem comes from the sheer number—now over 530 known arboviruses. Astrocytic infection without preceding endothelial infection is described in experimental studies of eastern equine encephalitis (EEE) virus (EEEV). One experimental study of the virus causing St. Louis encephalitis (SLE), in which low levels of viremia were produced in an effort to simulate conditions occurring in human infection, suggested that virus may gain access to the brain following preliminary invasion of and multiplication in olfactory neuroepithelium. Inflammation was similarly suppressed by cyclophosphamide, but without increasing mortality, in experimental infection with western equine encephalitis virus (WEEV) and EEEV, Sindbis virus, and Semliki Forest virus. During the acute disease, a peripheral leukocytosis has been noted in most patients, with neutrophils often predominating. Initial lumbar punctures were characterized by elevated cerebrospinal fluid (CSF) pressure, protein and white blood cells (WBC), with neutrophils again predominating. In the absence of a vaccine for SLE virus (SLEV), prevention depends on several factors, including sanitary management of water courses and sewage in urban settings. Provisional viral diagnosis during life depends on immunoglobulin M (IgM) capture enzyme-linked immunosorbent assay (ELISA) during acute illness or on elevations in other antibody titers.

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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Image of FIGURE 11.1

Section of the brain stem from a case of acute JE immunostained with an antibody to the virus. Immunostaining is seen in scattered neuronal cell bodies (arrows). Courtesy of T. Solomon.

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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Image of FIGURE 11.2

Low-power view of a section of cerebral cortex from a case of acute JE. Pale foci (arrows) represent foci of a cellular necrosis. PTAH stain.

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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Image of FIGURE 11.3

MRI of acute JE. Axial FLAIR image discloses hyperintensity of the basal ganglia bilaterally, right greater than left, with mild mass effect. Courtesy of Minh Dung and Bridget Wills, University of Oxford Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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1. Abu-Elyazeed, R.,, S. El-Sharkawy,, J. Olson,, B. Botros,, A. Soliman,, A. Salib,, C. Cummings,, and R. Arthur. 1996. Prevalence of anti-Rift-Valley-Fever IgM antibody in abattoir workers in the Nile Delta during the 1993 outbreak in Egypt. Bull. W. H. O. 74:155158.
2. Adamson, J. D.,, and S. Dubo. 1942. Clinical findings in encephalitis (western equine). Can. Public Health. J 33:288300.
3. Allner, K.,, C. L. Bradish,, R. Fitzgeorge,, and N. Nathanson. 1974- Modification by sodium aurothiomalate of the expression of virulence in mice by defined strains of Semliki Forest virus. J. Gen. Virol. 24:221228.
4. Anderson, J. E.,, and J.J. Rahal. 2002. Efficacy of interferon alpha 2-b and ribavirin against West Nile virus in vitro. Emerg. Infect. Dis. 8:107108.
5. Anderson, S. G. 1950. Murray Valley encephalitis: epidemiological aspects. Med. J. Aust. 1:97100.
6. Anderson, S. G. 1954- Murray Valley encephalitis and Australian X disease. J. Hyg. 52:447468, plus four plates.
7. Anic, K.,, I. Soldo,, L. Peric,, I. Karner,, and B. Barac. 1998. Tick-borne encephalitis in Eastern Croatia. Scand. J. Infect. Dis. 30:509512.
8. Asnis, D. S.,, R. Conetta,, A. A. Teixeira,, G. Waldman,, and B. A. Sampson. 2000. The West Nile Virus outbreak of 1999 in New York: the Flushing Hospital experience. Clin. Infect. Dis. 30:413418.
9. Ayres, J. C.,, and R. F. Feemster. 1949. The sequelae of eastern equine encephalitis. N. Engl. J.Med. 240:960962.
10. Bailey, P. 1958. VII. Czechoslovakiantick encephalitis. Neurology 8:890896. [This is a résumé of a report by K. Henner, and F. Hanzals, (1957) in Rev. Neurol 96:384408.
11. Baker, A. B.,, and H. H, Noran. 1942. Western variety of equine encephalitis in man. A clinicopathological study. Arch. Neurol. Psychiatr. 47:565587.
12. Balfour, H. H., Jr.,, R. A. Siem,, H. Bauer,, and P. G. Quie. 1973. California arbovirus (La Crosse) infections. I. Clinical and laboratory findings in 66 children with meningoencephalitis. Pediatrics 52:680691.
13. Bastian, F. O.,, R. D. Wende,, D. B. Singer,, and R. S. Zeller. 1975. Eastern equine encephalomyelitis. Histopathologic and ultra-structure changes with isolation of the virus in a human case. Am. J. Clin. Pathol. 64:1013.
14. Beaty, B. H.,, T. L. Jamnback,, S. W. Hildreth,, and K. L. Brown,. 1983. Rapid diagnosis of La Crosse virus infections: evaluation of serologic and antigen detection techniques for clinically relevant diagnosis of La Crosse encephalitis, p. 293302. In C. H. Calisher, and W. H. Thompson (ed.), California Serogroup Viruses. Alan R. Liss, Inc., New York, N.Y.
15. Beck, L. R.,, B. M. Lobitz,, and B. L. Wood. 2000. Remote sensing and human health: new sensors and new opportunities. Emerg. Infect. Dis. 6:217227.
16. Bedjanic, M.,, S. Rus,, J. Kmet,, and J. Vesenjak-Zmijanac 1955. Virus meningoencephalitis in Slovenia. 2. Clinical observations. Bull. W. H. O. 12:503512.
17. Bennett, N. M. 1976. Murray Valley encephalitis, 1974. Clinical features. Med. J. Aust. 2:446450.
18. Berther, F.-X.,, H. G. Zeller,, M.-T. Drouer,, J. Rauzier,, H.-P. Digoutte,, and V. Deube. 1997. Extensive nucleotide changes and deletions within the envelope glycoprotein gene of Euro-African West Nile viruses. J. Gen. Virol. 78:22932297.
19. Bia, F. J.,, G. F. Thornton,, A. J. Main,, C. K. Y. Fong,, and G. D. Hsiung. 1980. Western equine encephalitis mimicking herpes simplex encephalitis. JAMA 244:367369.
20. Booss, J.,, and N. Karabatsos,. Arthropod-borne virus encephalitis. In A. Nath, and J. R. Berger (ed.), Clinical Neurovirology, in press. Marcel-Dekker, New York, N.Y.
21. Bowen, C. S.,, T. R. Fashinell,, R. B. Dean,, and M. B. Gregg. 1976. Clinical aspects of human Venezuelan equine encephalitis in Texas. PAHO Bull 10:4757.
22. Briese, T.,, X.-Y. Jia,, C. Huang,, L. J. Grady,, and W. I. Lipkin. 1999. Identification of a Kunjin/West Nile-like flavivirus in brains of patients with New York encephalitis. Lancet 354:12611262.
23. Brinker, K. R.,, and T. P. Monath,. 1980. The acute disease, p. 503534. In T. P. Monath (ed.), St. Louis Encephalitis. American Public Health Assoc., Washington, D.C.
24. Brinker, K. R.,, G. Paulson,, T. P. Monath,, G. Wise,, and R. J. Fass. 1979. St. Louis encephalitis in Ohio, September 1975. Arch. Intern. Med. 139:561566.
25. Burke, D. S.,, A. Nisalak,, M. A. Ussery,, T. Laorakpongse,, and L. Chantavibul. 1985. Kinetics of IgM and IgG responses to Japanese encephalitis virus in human serum and cerebrospinal fluid. J. Infect. Dis. 151:10931099.
26. Candle, C.,, G. DiGuardo,, C. Eleni,, and M. Arispic. 2000. Clinical and neuropathological features of West Nile Virus equine encephalomyelitis in Italy. Equine Vet. J. 32:3135.
27. Cassidy, L. F.,, and J. L. Patterson. 1989. Mechanism of LaCrosse virus inhibition by ribavirin. Antimicrob. Agents Chemother. 33:20092011.
28. Ceausu, E.,, P. Ersciou,, P. Calistru,, D. Ispas,, O. Dorobat,, M. Homos,, C. Barbulescu,, I. Cojocaru,, C. V. Simion,, C. Cristea,, C. Oprea,, C. Dumitrescu,, D. Duiculescu,, I. Marcu,, C. Mociornita,, T. Stoicev,, I. Zolotusca,, C. Calomfirescu,, R. Rusu,, R. Hodrea,, S. Geamai,, and L. Paun. 1997. Clinical manifestations in the West Nile virus outbreak. Rom. J. Virol. 48:311.
29. Centers for Disease Control. 1986. St. Louis encephalitis— Baytown and Houston, Texas. Morb. Mortal. Wkly. Rep. 33:693695.
30. Centers for Disease Control and Prevention. 1998. Rift Valley fever—East Africa, 1997-1998. Morb. Mortal Wkly. Rep. 47:261264.
31. Centers for Disease Control and Prevention. 2000a. Outbreak of Rift Valley fever—Yemen, August-October 2000. Morb. Mortal. Wkly. Rep. 49:10651066.
32. Centers for Disease Control and Prevention. 2000b. Outbreak of Rift Valley fever—Saudi Arabia, August-October, 2000. Morb. Mortal. Wkly. Rep. 49:905908.
33. Centers for Disease Control and Prevention. 2000c. Update: outbreak of Rift Valley fever—Saudi Arabia, August-November 2000. Morb. Mortal. Wkly. Rep. 49:982985.
34. Centers for Disease Control and Prevention. 2001a. Summary of notifiable diseases. United States. 1999. Morb. Mortal. Wkly. Rep. 48:1101.
35. Centers for Disease Control and Prevention. 2001b. Serosurveys for West Nile Virus infection—New York and Connecticut counties, 2000. Morb. Mortal. Wkly. Rep. 50:3739.
36. Centers for Disease Control and Prevention. 2001c. Outbreak of Powassan encephalitis—Maine and Vermont, 1999-2001. Morb. Mortal. Wkly. Rep. 50:761764.
37. Centers for Disease Control and Prevention. 2002a. West Nile virus activity—United States, November 21-26, 2002. Morb. Mortal Wkly. Rep. 51:10721073.
38. Center for Disease Control and Prevention. 2002b. West Nile infection in organ donor and transplant recipients—Georgia and Florida. Morb. Mortal. Wkly. Rep. 51:790.
39. Centers for Disease Control and Prevention. 2002c. Intrauterine West Nile virus infection, New York, 2002. Morb. Mortal. Wkly. Rep. 51:11351136.
40. Centers for Disease Control and Prevention. 2002d. Acute flaccid paralysis syndrome associated with West Nile virus infection— Mississippi and Louisiana, July-August 2002. Morb. Mortal Wkly. Rep. 51:825828.
41. Chen, W.-J.,, K.-P. Hwang,, and A.-H. Fang. 1991. Detection of IgM antibodies from cerebrospinal fluid and sera of dengue fever patients. Southeast Asian J. Trop. Med. Public Health 22:660663.
42. Chimelli, L.,, M. DumaS'Hahn,, M. B. Netto,, R. G. Ramos,, M. Dias,, and F. Gray. 1990. Dengue: Neuropathological findings in 5 fatal cases from Brazil. Clin. Neuropathol 9:157162.
43. Chun, R. W. M.,, W. H. Thompson,, J. D. Grabow,, and C. G. Matthews. 1968. California arbovirus encephalitis in children. Neurology 18:369375.
44. Clarke, D. H. 1961. Two non-fatal human infections with the virus of eastern encephalitis. Am. J. Trop. Med. Hyg. 10:6770.
45. Clarke, D. H.,, and J. Casals,. 1965. Arboviruses; group B, p. 606658. In F. L. Horsfall, and I. Tamm (ed.), Viral and Rickettsial Infections of Man, 4th ed. J. B. Lippincott Co., Philadelphia, Pa.
46. Clarke, T. 2002. Break-bone fever. Nature 416:672674.
47. Daubney, R.,, and J. R. Hudson. 1931. Enzootic hepatitis or Rift Valley fever. An undescribed virus disease of sheep, cattle, and man from East Africa. J. Pathol. Bacteriol. 34:545579.
48. Davidson, M. M.,, H. Williams,, and J. A. Macleod. 1991. Louping ill in man: a forgotten disease. J. Infect. 23:241249.
49. Deresiewicz, R. L.,, S. L. Thaler,, L. Hsu,, and A. A. Zamani. 1997. Clinical and neuroradiographic manifestations of eastern equine encephalitis. N. Engl. J. Med. 336:18671874.
50. Desai, A.,, S. K. Sanker,, V. Ravi,, A. Chandramaki,, and M. Gourie-Devi. 1995a. Japanese encephalitis virus antigen in human brain and its topographic distribution. Acta Neuropathol. 89:368373.
51. Desai, A.,, V. Ravi,, A. Chandramuki,, and M. Gourie-Devi. 1995b. Detection of immune complexes in the CSF of Japanese encephalitis patients: correlation of findings with outcome. Intervirology 37:352355.
52. Dickerson, R. B.,, J. R. Newton,, and J. E. Hanson. 1952. Diagnosis and immediate prognosis of Japanese B encephalitis. Am. J. Med. 12:277288.
53. Doherty, P. C.,, and A. W. Reid. 1971. Experimental louping ill in sheep and lambs. 2. Neuropathology. J. Comp. Pathol. 81:331337.
54. Doherty, P. C.,, and J. T. Vantsis. 1973. Louping ill encephalomyelitis in the sheep. 7. Influence of immune status on neuropathology. J. Comp. Pathol. 83:481491.
55. Doherty, R. L.,, J. G. Carley,, M. R. Cremer,, J. T. Rendle-Short,, L. J. Hopkins,, D. H. Herbert,, A. J. Caro,, and W. B. Stephens. 1972. Murray Valley encephalitis in eastern Australia, 1971. Med. J. Aust. 2:11701173.
56. Downs, W. G. 1982. The Rockefeller Foundation virus program: 1951-1971 with update to 1981. Annu. Rev. Med. 33:129.
57. Dykers, T. L.,, K. L. Brown,, C. B. Gunderson,, and B. J. Beatty. 1985. Rapid diagnosis of specific immunoglobulin M in cerebrospinal fluid. J. Clin. Microbiol. 22:740744.
58. Earnest, M. P.,, H. A. Goolishian,, J. R. Calverly,, R. O. Hayes,, and H. R. Hill. 1971. Neurologic, intellectual, and psychologic sequelae following western encephalitis. A follow-up study of 35 cases. Neurology 21:969974.
59. Ehrenkranz, N. J.,, M. C. Sinclair,, E. Buff,, and D. O. Lyman. 1970. The natural occurrence of Venezuelan equine encephalitis in the United States. First case and epidemiologic investigations. N. Engl. J. Med. 282:298302.
60. Ehrenkranz, N. J.,, and A. K. Ventura. 1974. Venezuelan equine encephalitis in man. Annu. Rev. Med. 25:914.
61. Eklund, C. M. 1946. Human encephalitis of the western equine type in Minnesota in 1941. Clinical and epidemiological study of serologically positive cases. Am. J. Hyg. 43:171193.
62. Eklund, C 1958. VI. Colorado tick fever. Neurology 8:889.
63. Eklund, C. M.,, and A. Blumstein. 1938. The relation of human encephalitis to encephalomyelitis in horses. JAMA 111:17341735.
64. Eklund, C. M.,, G. M. Kohls,, and J. M. Brennan. 1955. Distribution of Colorado tick fever and virus-carrying ticks. JAMA 157:335337.
65. Embil, J. A.,, P. Camfield,, H. Artsob,, and D. P. Chase. 1983. Powassan virus encephalitis resembling herpes simplex encephalitis. Arch. Intern. Med. 143:341343.
66. Farber, S.,, A. Hill,, M. L. Connerly,, and J. H. Dingle. 1940. Encephalitis in infants and children caused by the virus of the eastern variety of equine encephalitis. JAMA 114:17251731.
67. Feemster, R. F. 1957. Equine encephalitis in Massachusetts. N. Engl. J. Med. 257:701704.
68. Fernandez, R. J.,, and E. C. Dooling. 1982. Eastern equine encephalitis mimicking herpes simplex encephalitis. Neurology 32(2):A178.
69. Finley, K. H.,, and N. Riggs,. 1980. Convalescence and sequelae, p. 535550. In T. P. Monath (ed.), St. Louis Encephalitis. American Public Health Assoc., Washington, D.C.
70. Finley, K. H.,, L. H. Fitzgerald,, R. W. Richter,, N. Riggs,, and J. T. Shelton. 1967. Western encephalitis and cerebral ontogenesis. Arch. Neurol. 16:140164.
71. Florio, L.,, M. S. Miller,, and E. R. Mugrage. 1952. Colorado tick fever: recovery of virus from human spinal fluid. J. Infect. Dis. 91:285289.
72. Fradin, M. S. 1998. Mosquitoes and mosquito repellants: a clinician's guide. Ann. Intern. Med. 128:931940.
73. French, E. L. 1952. Murray Valley encephalitis: isolation and characterization of the etiological agent. Med. J. Aust. 1:100103.
74. Gadoth, N.,, S. Weitzman,, and E. E. Lehmann. 1979. Acute anterior myelitis complicating West Nile fever. Arch. Neurol. 36:172173.
75. Gajanana, A.,, V. Thenmozhi,, P. P. Samuel,, and R. Reuben. 1995. A community-based study of subclinical flavivirus infections in an area of Tamil Nadu, India where Japanese encephalitis in endemic. Bull. W.H.O. 73:237244.
76. Gardner, J. J.,, and M. G. Reyes,. 1980. Pathology, p. 551569. In T. P. Monath (ed.), St. Louis Encephalitis. American Public Health Assoc., Washington, D.C.
77. Garen, P. D.,, T. F. Tsai,, and J. M. Powers. 1999. Human eastern equine encephalitis: immunohistochemistry and ultrastructure. Mol. Pathol. 12:646652.
78. Gatus, B. J.,, and M. R. Rose. 1983. Japanese B encephalitis:epidemiological, clinical, and pathological aspects. J. Infect.6:213218.
79. George, S.,, M. Gourie-Devi,, J. A. Rao,, S. R. Prasad,, and K. M. Pavri. 1984. Isolation of West Nile virus from the brains of children who had died of encephalitis. Bull. W. H. O. 62:879882.
80. Gholam, B. I. A.,, S. Puksa,, and J. P. Provias. 1999. Powassan encephalitis: a case report with neuropathology and literature review. Can. Med. Assoc. J. 161:14191422.
81. Goldblum, N.,, V. V. Sterk,, and B. Paderski. 1954. West Nile fever. The clinical features of the disease and the isolation of West Nile virus from the blood of nine human cases. Am. J. Hyg. 59:89103.
82. Goldfield, M.,, and O. Sussman. 1968. The 1959 outbreak of eastern encephalitis in New Jersey. I. Introduction and description of outbreak. Am. J. Epidemiol. 87:110.
83. Goodpasture, H. C.,, J. D. Poland,, D. B. Francy,, G. S. Bowen,, and K. A. Horn. 1978. Colorado tick fever: clinical, epidemiologic, and laboratory aspects of 228 cases in Colorado in 1977-1974- Ann. Intern. Med. 88:303310.
84. Grascenkov, N. I. 1964. Tick-borne encephalitis in the USSR. Bull.W.H.O.30:187196.
85. Griffin, D. E.,, and J. M. Hardwick. 1997. Regulators of apoptosis on the road to persistent alphavirus infection. Annu. Rev. Microbiol. 51:565592.
86. Grimley, P. M. 1983. Arbovirus encephalitis: which road traveled by makes all the difference? Lab. Invest. 48:369371.
87. Grinschgl, G. 1955. Virus meningo-encephalitis in Austria. 2. Clinical features, pathology, and diagnosis. Bull. W. H.O. 12:535564.
88. Gubler, D. J. 1998. Dengue and dengue hemorrhagic fever. Clin. Microbiol. Rev. 11:480496.
89. Gunther, G.,, M. Haglund,, L. Lindquist,, M. Forsgren,, and B. Skoldenberg. 1997. Tick-borne encephalitis in Sweden in relation to aseptic meningoencephalitis of unknown etiology: a prospective study of clinical course and outcome. J. Neurol. 244:230238.
90. Hales, S.,, N. de Wet,, J. Maindonald,, and A. Woodward. 2002. Potential effect of population and climate changes on global distribution of Dengue fever: an empirical model. Lancet 360:830834.
91. Halstead, S. B. 1988. Pathogenesis of dengue: challenges to molecular biology. Science 239:476481.
92. Halstead, S. B.,, and C. R. Grosz. 1962. Subclinical Japanese encephalitis. I. Infection of Americans with limited residence in Korea. Am. J. Hyg. 75:190201.
93. Han, L. L.,, F. Popovici,, J. P. Alexander, Jr.,, V. Laurentia,, L. A. Tengelsen,, C. Cernescu,, H. E. Gary Jr.,, N. Ion-Nedelcu,, G. L. Campbell,, and T. F. Tsai. 1999. Risk factors for West Nile virus infection and meningoencephalitis, Romania, 1996. J. Infect. Dis. 179:230233.
94. Hase, T. 1993. Virus-neuron interactions in the mouse brain infected with Japanese encephalitis virus. Virchows Arch. B Cell Pathol, lncl. Mol. Pathol. 64:162170.
95. Hayes, E. B.,, and D. J. Gubler. 1992. Dengue and dengue hemorrhagic fever. Pediatr. Infect. Dis. J. 11:311317.
96. Heinz, F. X.,, and C. W. Mandl. 1993. The molecular biology of tick-borne encephalitis virus. APMIS 101:735745.
97. Heinz, F. S.,, M. Roggendorf,, H. Hofmann,, C. Kunz,, and F. Deinhardt. 1981. Comparison of two different enzyme immunoassays for detection of immunoglobulin M antibodies against tick borne encephalitis virus in serum and cerebrospinal fluid. J. Clin. Microbiol. 14:141146.
98. Heinz, F. X.,, R. Berger,, W. Tuma,, and C. Kunz. 1983. A topological and functional model of epitopes on the structural glycoprotein of tick-borne encephalitis virus defined by monoclonal antibodies. Virology 126:525537.
99. Hilty, M. D.,, R. E. Hayes,, R. H. Azimi,, and H. G. Cramblett. 1972. California encephalitis in children. Am. J. Dis. Child. 124:530533.
100. Hoke, C. H., Jr.,, D. W. Vaughn,, A. Nisalak,, P. Intralawan,, S. Poolsuppasit,, V. Jongsawas,, U. Titsyakorn,, and R. T. Johnson. 1992. Effect of high dose dexamethasone on the outcome of acute encephalitis due to Japanese encephalitis virus. J. Infect. Dis. 165:631637.
101. Hoogstraal, H.,, J. M. Meegan,, and G. M. Khalil. 1979. The Rift Valley fever epizootic in Egypt 1977-1978. 2. Ecological and entomological studies. Trans. R. Soc. Trop. Med. Hyg. 73:624629.
102. Huang, C. H. 1982. Studies of Japanese encephalitis in China. Adv. Virus Res. 27:71101.
103. Huang, C.,, W. H. Thompson,, N. Karabatsos,, L. Grady,, and W. P. Campbell. 1997. Evidence that fatal human infections with La Cross virus may be associated with a narrow range of genotypes. Virus Res. 481:143148.
104. Hubalek, Z.,, and J. Halouzka. 1999. West Nile fever—a reemerging mosquito-borne viral disease in Europe. Emerg. Infect. Dis. 5:643650.
105. Innes, B. L., 1995. Dengue and dengue hemorrhagic fever, p. 103146. In J. S. Porterfield (ed.), Exotic Viral Infections. Chapman and Hall Medical, London, United Kingdom.
106. Ishii, T.,, M. Matsushita,, and S. Hamada. 1977. Characteristic residual neuropathological features in Japanese B encephalitis. Acta Neuropathol. 38:181186.
107. Iwasaki, Y.,, J. X. Zhao,, T. Yamamoto,, and H. Konno. 1986. Immunohistochemical demonstration of viral antigens in Japanese encephalitis. Acta Neuropathol. 70:7981.
108. Iwasaki, Y.,, K. Sako,, I. Tsumoda,, and Y. Ohara. 1993. Phenotypes of mononuclear cell infiltrates in human central nervous system. Acta Neuropathol. 85:653657.
109. Janssen, H. L. A.,, H. P. Bienfait,, C. L. Jansen,, S. G. van Duinen,, R. Vriesendorp,, R. J. Schimsheimer,, J. Groen,, and A. D. M. E. Osterhaus. 1998. Fatal cerebral-edema associated with primary dengue infection. J. Infect. 36:344346.
110. Johnson, R. T. 1965. Virus invasion of the central nervous system. A study of Sindbis virus infection in the mouse using fluorescent antibody. Am. J. Pathol. 46:929943.
111. Johnson, R. T. 1998. Viral Infections of the Nervous System, 2nd ed., p. 109125. Lippincott-Raven, Philadelphia, Pa.
112. Johnson, R. T.,, D. S. Burke,, M. Elwell,, C. J. H. Leake,, A. Nisalak,, C. H. Hoke,, and W. Lorsomrudee. 1985. Japanese encephalitis: immunocytochemical studies of viral antigen and inflammatory cells in fatal cases. Ann. Neurol. 18:567573.
113. Jordan, I.,, T. Briese,, N. Fischer,, J. Y.-L. Lau,, and W. I. Lipkin. 2000. Ribavirin inhibits West Nile virus replication and cytopathic effect in neural cells. J. Infect. Dis. 182:12131217.
114. Kaiser, R.,, and H. Holzmann. 2000. Laboratory findings in tick-borne encephalitis—correlation with clinical outcome. Infection 28:7884.
115. Kalita, J.,, and U. K. Misra. 1998. EEG in Japanese encephalitis: a clinicoradiological correlation. Electroenceph. Clin. Neurophysiol. 106:238243.
116. Kankirawatana, P.,, K. Chokephaibulkit,, P. Puthavathana,, S. Yoksan,, S. Apintanapong,, and V. Pongthapisit. 2000. Dengue infection presenting with central nervous system manifestation. J. Child Neurol. 15:544547.
117. Kappus, K. D.,, T. P. Monath,, R. M. Kaminski,, and C. H. Calisher,. 1983. Reported encephalitis associated with California serogroup virus infections in the United States 1963— 1981, p. 3141. In C. H. Calisher, and W. H. Thompson (ed.), California Serogroup Viruses. Alan R. Liss Inc., New York, N.Y.
118. Karabatsos, N. (ed.). 1985. International Catalogue of Arboviruses Including Certain Other Viruses of Vertebrates, 3rd ed. American Society of Tropical Medicine and Hygiene, San Antonio, Tex.
119. Karabatsos, N.,, A. L. Lewis,, C. H. Calisher,, A. R. Hunt,, and J. T. Roehrig. 1988. Identification of highlands J virus from a Florida horse. Am. J. Trop. Med. Hyg. 39:603606.
120. Karak, J. D.,, Y. Aynor,, and C. J. Peters. 1982. A Rift Valley fever vaccine trial. I. Side effects and serologic response over a six-month follow up. Am. J. Epidemiol. 116:808820.
121. Kay, B. H. 1980. Towards prediction and surveillance of Murray Valley encephalitis activity in Australia. Aust. J. Exp. Biol. Med. Sci. 58:6776.
122. Kim, J. H.,, J. Booss,, E. E. Manuelidis,, and C. C. Duncan. 1985. Human eastern equine encephalitis: electron microscopic study of a brain biopsy. Am. J. Clin. Pathol. 84:223227.
123. Kmet, J.,, J. Vesenjak'Zmijanac,, M. Bedjanic,, and S. Rus. 1955. Virus meningoencephalitis in Slovenia. 1. Epidemiological observations. Bull. W.H.O. 12:491501.
124. Kokernot, R. H.,, H. R. Shinefield,, and W. A. Longshore, Jr. 1953. The 1952 outbreak of encephalitis in California. Differential diagnosis. Cal. Med. 79:7377.
125. Kuno, G.,, H. Artsob,, N. Karabatsos,, K. R. Tsuchiya,, and G. J. J. Chang. 2001. Genomic sequencing of deer tick virus and the phylogeny of the Powassan-related viruses of North America. Am. J. Trop. Med. 65:671676.
126. Lanciotti, R. S.,, J. T. Roehrig,, V. Deubel,, J. Smith,, M. Parker,, K. Steele,, B. Crise,, K. E. Volpe,, M. B. Crabtree,, J. H. Scherret,, R. A. Hall,, J. S. MacKenzie,, C. B. Cropp,, B. Panigrahy,, E. Ostlund,, B. Schmitt,, M. Malkinson,, C. Banet,, J. Weissman,, N. Komar,, H. M. Savage,, W. Stone,, T. McNamara,, and D. J. Gubler. 1999. Origin of the West Nile virus responsible for an outbreak of encephalitis in the Northeastern United States. Science 286:23332337.
127. Laughlin, L. W.,, J. M. Meegan,, L. J. Strausbaugh,, D. M. Morens,, and R. H. Watten. 1979. Epidemic Rift Valley fever in Egypt: observations of the spectrum of human illness. Trans. R. Soc. Trop. Med. Hyg. 73:630633.
128. Leech, R. W.,, J. C. Harris,, and R. W. Johnson. 1981. 1975 encephalitis epidemic in North Dakota and western Minnesota. An epidemiological, clinical and neuropathologic study. Minn. Med. 64:545548.
129. Lehmann, N. I.,, I. D. Gust,, and R. Doherty. 1976. Isolation of Murray Valley encephalitis virus from the brain of three patients with encephalitis. Med. J. Aust. 2:450454-
130. Levine, B.,, J. M. Hardwick,, B. D. Trapp,, T. O. Crawford,, R. C. Bolinger,, and D. E. Griffin. 1991. Antibody-mediated clearance of alphavirus infection from neurons. Science 254:856860.
131. Levine, B.,, J. E. Goldman,, H. H. Jiang,, D. E. Griffin,, and J. M. Hardwick. 1996. Bcl-2 protects mice against fatal alphavirus encephalitis. Proc. Natl. Acad. Sci. USA 93:48104815.
132. Li, Z. S.,, S. F. Hong,, and N. L. Ghong. 1988. Immunohistochemical study of Japanese B encephalitis. China Med. J. 101:768771.
133. Linthicum, J. J.,, A. Anyamba,, C. J. Tucker,, P. W. Kelley,, M. E Myers,, and C. J. Peters. 1999. Climate and satellite indicators to forecast Rift Valley fever epidemics in Kenya. Science 285:397400.
134. Liou, M.-L.,, and C. Y. Hsu. 1998. Japanese encephalitis virus is transported across the cerebral blood vessels by endocytosis in mouse brain. Cell Tissue Res. 293:389394-
135. Lord, R. D. 1974. History and geographic distribution of Venezuelan equine encephalitis. Bull. Pan Am. Health Org. 8:100110.
136. Lum, L. C. S.,, S. K. Lam,, Y. S. Choy,, R. George,, and E. Harun. 1996. Dengue encephalitis: a true entity? Am. J. Trop. Med. Hyg. 54:256259.
137. Lvov, D. K.,, A. M. Butenko,, V. L. Gromashevsky,, V. P. Larichev,, S. Y. Gaidamovich,, O. I. Vyshemirsky,, A. N. Zhukov,, V. V. Lazorenko,, V. M. Salko,, A. I. Kovtunov,, K. M. Galimzyanov,, A. E. Platonov,, T. N. Morozova,, N. V. Khutoretskaya,, E. O. Shishkina,, and T. M. Skvortsova. 2000. Isolation of two strains of West Nile virus during an outbreak in southern Russia. Emerg. Infect. Dis. 6:373376.
138. Mackenzie, J. S.,, and A. K. Broom. 1995. Australian X Disease, Murray Valley encephalitis and the French connection. Vet. Microbiol. 46:7590.
139. Mackenzie, J. S.,, D. W. Smith,, A. K. Brown,, and M. R. Bucens. 1993. Australian encephalitis in Western Australia, 1978— 1991. Med. J. Aust. 158:591595.
140. Mackenzie, J. S.,, M. D. Lindsay,, R. J. Coelen,, A. K. Broom,, R. A. Hall,, and D. W. Smith. 1994. Arboviruses causing human disease in the Australasian zoographic region. Arch. Virol. 136:447467.
141. Marbert, K.,, N. Goldblum,, V. V. Sterk,, W. Jasinska-Klingberg,, and M. A. Klingberg. 1956. The natural history of West Nile fever. I. Clinical observations during an epidemic in Israel. Am. J. Hyg. 64:259269.
142. Mathur, A.,, N. Khanna,, and U. C Chaturvedi. 1992. Breakdown of blood-brain barrier by virus-induced cytokine during Japanese encephalitis virus infection. Int. J. Exp. Pathol. 73:603611.
143. Mcintosh, B. M.,, P. G. Jupp,, I. Dos Santos,, and G. M. Meenehan. 1976. Epidemics of West Nile and Sindbis viruses in South Africa with Culex (Culex) univittatus theobald as vector. S. Afr. J. Sci. 72:295300.
144. Mcjunkin, J. E.,, R. R Khan,, and T. R Tsai. 1998. California-LaCrosse encephalitis. Infect. Dis. Clin. N. Am. 12:8393.
145. Mcjunkin, J. E.,, E. C. DeLos Reyes,, J. E. Irazuzta,, M. J. Caceres,, R. R. Khan,, L. L. Minnich,, K. D. Fu,, G. D. Lovett,, T. Tsai,, and A. Thompson. 2001. LaCrosse encephalitis in children. N. Engl. J. Med. 344:801807.
146. Medovy, H. 1942. Western equine encephalitis in infants. Can. Public Health J. 33:307312.
147. Meegan, J. M. 1979. The Rift Valleyfever epizootic in Egypt 1977-78.1. Description of the epizootic and virological studies. R. Soc. Trop. Med. Hyg. 73:618623.
148. Meegan, J. M.,, H. Hoogstraal,, and M. I. Moussa. 1979. An epizootic of Rift Valley fever in Egypt in 1977. Vet. Rec. 105:124125.
149. Melnick, J. L.,, J. R. Paul,, J. T. Riordan,, V. H. Barnett,, N. Goldblum,, and E. Zabin. 1951. Isolation from human sera in Egypt of a virus apparently identical to West Nile Virus. Proc. Soc. Exp. Biol. Med. 77:661665.
150. Misra, U. K.,, J. Kalita,, and M. Srivastava. 1998. Prognosis of Japanese encephalitis: a multivariate analysis. J. Neurol. Sci. 161:143147.
151. Miyake, M. 1964. The pathology of Japanese encephalitis: a review. Bull. W.H.O. 30:153160.
152. Monath, T. P., 1978. Central nervous system infections (Acute), p. 261294. In G. D. Hsiung, and R. H. Green (ed.), Virology and Rickettsiology, vol. I, part 2. CRC Press, West Palm Beach, Fla.
153. Monath, T. P., 1980. Epidemiology, p. 239312. In T. P. Monath (ed.), St. Louis Encephalitis. American Public Health Assoc., Washington, D.C.
154. Monath, T. P.,, and T. F. Tsai. 1987. St Louis encephalitis: lessons from the last decade. Am. J. Trop. Med. Hyg. 37(3 Suppl.):40S59S
155. Monath, T. R.,, and T. F. Tsai,. 1997. Flaviviruses, p. 11331185. In D. D. Richman,, R. J. Whitley,, and F. G. Hayden (ed.), Clinical Virology. Churchill Livingstone, New York, N.Y.
156. Monath, T. R.,, B. C. Cropp,, and A. K. Harrison. 1983. Mode of entry of a neurotropic arbovirus into the central nervous system. Lab. Invest. 48:399410.
157. Murali'Krishna, K.,, V. Ravi,, and R. Manjunath. 1994. Cytotoxic T lymphocytes against Japanese encephalitis virus: effector cell phenotype, target specificity and in vitro clearance. J. Gen. Virol. 75:799807.
158. Murali'Krishna, K.,, V. Ravi,, and R. Manjumath. 1996. Protection of adult but not newborn mice against intra cerebral challenge with Japanese encephalitis virus by adoptively transferred virus-specific T lymphocytes: requirement of LST4+ cells. J. Gen. Virol. 77:705714.
159. Murgod, U. A.,, U. B. Muthane,, V. Ravi,, S. Radhesh,, and A. Desai. 2001. Persistent movement disorders following Japanese encephalitis. Neurology 57:23132315.
160. Murphy, E. A.,, and S. G. Whitfield. 1970. Eastern equine encephalitis virus infection: electron microscopic studies of mouse central nervous system. Exp. Mol. Pathol. 13:131146.
161. Nash, D.,, F. Mostashari,, A. Fine,, J. Miller,, D. O'Leary,, K. Murray,, A. Huang,, A. Rosenberg,, A. Greenberg,, M. Sherman,, S. Wong,, and M. Laytonforthe1999WestNileOutbreakResponseWorkingGroup. 2001. The outbreak of West Nile virus infection in the New York City area in 1999. N. Engl. J. Med. 344:18071814.
162. Nichter, C. A.,, S. G. Pavlakis,, U. Shaikh,, K. A. Cherian,, J. Dobrosyzcki,, M. E. Porricola,, and I. Chatturvedi. 2000. Rhombencephalitis caused by West Nile Fever virus. Neurology 55:153.
163. Niklasson, B.,, C. J. Peters,, M. Grandien,, and O. Wood. 1984-Detection of human immunoglobulins G and M antibodies to Rift Valley Fever virus by enzyme-linked immunosorbent assay. J. Clin. Microbiol. 19:225229.
164. Nimmannitya, S.,, U. Thisyakorn,, and V. Hemsrichart. 1987. Dengue haemorrhagic fever with unusual manifestations. Southeast Asian J. Trop. Med. Public Health 18:399406.
165. Ogawa, M.,, H. Okubu,, Y. Tsunji,, N. Yasui,, and K. Someda. 1973. Chronic progressive encephalitis occurring 13 years after Russian spring-summer encephalitis. J. Neurol. Sci. 19:363373.
166. Okhuysen, P. C.,, J. K. Crane,, and J. Pappas. 1993. St Louis encephalitis in patients with human immunodeficiency virus infection. Clin. Infect. Dis. 17:140141.
167. Osetowska, E., 1970. Tick-borne encephalitides, p. 182193. In R. Debre, and J. Celers (ed.), Clinical Virology. The Evaluation and Management of Human Viral Infections. W. B. Saunders Co., Philadelphia, Pa.
168. Osetowska, E. 1977. Tissue Neuropathology of Viral and Allergic Encephalitides, p. 93109. National Technical Information Service, Springfield, Va.
169. Patey, O.,, L. Ollivaud,, J. Breuil, and C Lafaix. 1993. Unusual neurologic manifestations occurring during dengue fever infection. Am. J. Trop. Med. Hyg. 48:793802.
170. Pathak, S.,, and H. E. Webb. 1974. Possible mechanism for the transport of Semliki Forest virus into and within mouse brain. An electron microscopic study. J. Neurol. Sci. 23:175184.
171. Pavlovsky, E. N. 1966. Natural Nodality of Transmissible Disease, with Special Reference to the Landscape Epidemiology of Zooanthroponoses.(Translated by F. K. Pious, Jr.; English translation edited by N. D. Levine.) University of Illinois Press, Urbana, III.
172. Pavri, K. 1989. Clinical, clinicopathologic, and hematologic features of Kyasanur Forest disease. Rev. Infect. Dis. 11:S854S859.
173. Petersen, L. R.,, and A. A. Martin. 2002. West Nile virus: a primer for the clinician. Ann. Intern. Med. 137:173179.
174. Platonov, A. E.,, G. A. Shipulin,, O. Yu. Shipulina,, E. N. Tyutyunnik,, T. I. Frolochkina,, R. S. Lanciotti,, S. Yazyshina,, O. V. Platinov,, I. L. Obukhov,, A. N. Zhukov,, Y. Ya. Vengerov,, and V. I. Pokrovskii. 2001. Outbreak of West Nile virus infection, Volgograd region, Russia. 1999. Emerg. Infect. Dis. 1:128132.
175. Pradham, S.,, N. Pandey,, S. Shashank,, R. K. Gupta,, and A. Mathur. 1999. Parkinsonism due to predominant involvement of substantia nigra in Japanese encephalitis. Neurology 53:17811786.
176. Pruzanski, W.,, and R. Altman. 1962. Encephalitis due to West Nile fever virus. World Neurol. 3:524527.
177. Public Health Service. 1935. Report on the St. Louis Outbreak of Encephalitis. Public Health Bulletin 214. Public Health Service, U.S. Department of the Treasury. U.S. Government Printing Office, Washington, D.C.
178. Quong, T. L. 1942. The pathology of western equine encephalitis. 18 human cases, Manitoba epidemic, 1941. Can. Public Health J. 33:300306, with fold-out chart following p. 306.
179. Radsel-Medvescek, A.,, M. Marolt-Gomiscek,, and M. Gajsek-Zima,. 1980. Clinical characteristics of patients with TBE treated at the University Medical Center Hospital for Infectious Diseases in Ljubljana during the years 1974 and 1977, p. 277280. In J. Vesenjak-Hirjan,, J. S. Porterfield,, and E. Arslanagaic (ed.), Arboviruses in Mediterranean Countries. Gustav Fischer Verlag, Stuttgart, Germany.
180. Rappole, J. H.,, S. R. Derrickson,, and Z. Hubalek. 2000. Migratory birds and spread of West Nile virus in the western hemisphere. Emerg. Infect. Dis. 6:319328.
181. Ravi, V.,, S. Parida,, A. Chandramuki,, M. Gourie-Devi,, and G. E. Grau. 1997. Correlation of TNF levels in the serum and CSF in Japanese encephalitis patients. J. Med. Virol. 51:132136.
182. Ravi, V.,, A. Desai,, S. K. Shankar,, and M. Gourie-Devi,. 2000. Japanese encephalitis, p. 231257. In L. E. Davis, and P. G. E. Kennedy (ed.), Infectious Diseases of the Nervous System. Butterworth-Heinemann, Oxford, United Kingdom.
183. Reyes, M. G.,, J. J. Gardner,, J. D. Poland,, and T. P. Monath. 1981. St. Louis encephalitis: quantitative histologic and immunofluorescent studies. Arch. Neurol. 38:329334.
184. Rigau-Perez, R. G.,, G. G. Clark,, D. J. Gubler,, P. Reiter,, E. J. Sanderes,, and A. V. Vorndam. 1998. Dengue and dengue hemorrhagic fever. Lancet 352:971977.
185. Riou, O.,, B. Philippe,, A. Jouan,, I. Coulibaly,, M. Mondo,, and J. P. Digoutte. 1989. Neurologic and neurosensory forms of Rift Valley fever (in French). Bull. Soc. Path. Exot. Ses Filiales 82:605610.
186. Rivas, F.,, L. A. Diaz,, V. M. Cardenas,, E. Daza,, L. Bruaon,, A. Alcala,, O. DelaHoz,, F. M. Caceres,, G. Aristizabal,, J. W. Martinez,, D. Revelo,, F. DelaHoz,, J. Boshell,, T. Camacho,, L. Calderon,, V. A. Olano,, L. I. Villareal,, D. Roselli,, G. Alverez,, G. Ludwig,, and T. Tsai. 1997. Epidemic Venezuelan equine encephalitis in LaGuajira, Columbia, 1995. J. Infect. Dis. 175:828832.
187. Robertson, E. G.,, and H. McLorinan. 1952. Murray Valley encephalitis: clinical aspects. Med. J. Aust. 1:103107.
188. Rose, M. R.,, S. M. Hughes,, and B. J. Gatus. 1983. A case of Japanese B encephalitis imported into the United Kingdom. J. Infect. 6:261265.
189. Row, D.,, P. Weinstein,, and S. Murray-Smith, 1996. Dengue fever with encephalopathy in Australia. Am. J. Trop. Med. Hyg. 54:253255.
190. Rozdilsky, B.,, H. E. Robertson,, and J. Chorney. 1968. Western encephalitis: report of eight fatal cases: Saskatchewan epidemic, 1965. Can. Med. Assoc. J. 98:7986.
191. Rust, R. S.,, W. H. Thompson,, C. G. Matthews,, B. J. Beaty,, and R. W. M. Chun. 1999. LaCrosse and other forms of encephalitis. J. Child. Neurol. 14:114.
192. Sampson, B. A.,, C. Ambrosi,, A. Chariot,, K. Reiber,, J. F. Veress,, and V. Armbrustmacher. 2000. The pathology of human West Nile virus infection. Hum. Pathol. 31:527531.
193. Schellinger, P. D.,, E. Schmutzhard,, J. B. Fiebach,, B. Pfausler,, H. Maier,, and S. Schwab. 2000. Poliomyelitic-like illness in Central European encephalitis. Neurology 55:299302.
194. Schlesinger, R. W. 1980. The Togaviruses; Biology, Structure and Replication. Academic Press, New York, N.Y.
195. Shiraki, H., 1970. Japanese Encephalitis, p. 155175. In R. Debre, and J. Celers (ed.), Clinical Virology. The Evaluation and Management of Human Viral Infections. W. B. Saunders Co., Philadelphia, Pa..
196. Shope, R. E. 1980. Arbovirus-related encephalitis. Yale J. Biol. Med. 53:9399.
197. Siam, A. L.,, J. M. Meegan,, and K. F. Garbawi, 1980. Rift Valley Fever ocular manifestations: observations during the 1977 epidemic in Egypt. Br. J. Ophthalmol. 64:366374.
198. Silber, L. A.,, and V. D. Soloviev. 1946. FarEasterntick-bornespring-summer (spring)encephalitis. Am. Rev. Soviet Med. (special suppl.).
199. Silver, H. K.,, G. Meiklejohn,, and C. H. Kempe. 1961. Colorado tick fever. Am. J. Dis. Child. 101:3036.
200. Smadel, J. E.,, P. Bailey,, and A. B. Baker. 1958. Sequelae of the arthropod-borne encephalitides. Neurology 8:878896.
201. Smithburn, K. C.,, T. P. Hughes,, A. W. Burke,, and J. H. Paul. 1940. A neurotropic virus isolated from the blood of a native of Uganda. Am. J. Trop. Med. 20:471492.
202. Smorodintsev, A. A. 1958. Tick-borne spring-summer encephalitis. Prog. Med. Virol 1:210248.
203. Solomon, T.,, and M. Mallewa. 2001. Dengue and other emerging flaviviruses. J. Infect. 42:104115.
204. Solomon, T.,, N. M. Dung,, D. W. Vaughn,, R. Kneen,, L. T. T. Thao,, B. Raengsakulrach,, H. T. Loan,, N. P. J. Day,, J. Far- rar,, K. S. A. Myint,, M. J. Warrell,, W. S. James,, A. Nisalak,, and N. J. White. 2000. Neurological manifestations of dengue infection. Lancet 355:10531059.
205. Solomon, T.,, N. M. Dung,, B. Wills,, R. Kneen,, M. Gainsborough,, T. V. Diet,, T. T. N. Thuy,, H. T. Loan,, V. C Khanh,, D. W. Vaughn,, N. J. White,, and J. J. Farrar. 2003. Interferon alfa-2a in Japanese encephalitis: a randomized double-blind placebo controlled trial. Lancet 361:821826.
206. Southam, C. M.,, and A. E. Moore. 1954. Induced virus infections in man by the Egypt isolates of West Nile virus. Am. J. Trop. Med. Hyg. 3:1950.
207. Southern, P. M., Jr.,, J. W. Smith,, J. P. Luby,, J. A. Barnett,, and J. P. Sanford. 1969. Clinical and laboratory features of epidemic St. Louis encephalitis. Ann. Intern. Med. 71:681689.
208. Spruance, S. L.,, and A. Bailey. 1973. Colorado tick fever. A review of 115 laboratory-confirmed cases. Arch. Intern. Med. 131:288293.
209. Steele, K. E.,, M. J. Linn,, R. J. Schoepp,, N. Komar,, T. W. Geisbert,, R. M. Manduca,, P. P. Calle,, B. L. Raphael,, N. A. Panella,, and T. S. McNamara. 2000. Pathology of fatal West Nile virus infections in native and exotic birds during the 1999 outbreak in New York City, New York. Vet. Pathol. 37:208224.
210. Suzuki, M.,, and C. A. Phillips. 1966. St. Louis encephalitis. A histopathologic study of the fatal cases from the Houston epidemic in 1964. Arch. Pathol. 81:4754.
211. Tardei, G.,, S. Ruta,, V. Chitu,, C. Rossi,, T. F. Tsai,, and C. Cernescu. 2000. Evaluation of immunoglobulin M (IgM) and IgG enzyme immunoassays in serologic diagnosis of West Nile virus encephalitis. J. Clin. Microbiol. 38:22322239.
212. Tsai, T. F. 1992. Arboviral infections: general considerations for prevention, diagnosis, and treatment in travelers. Semin. Pediatr. Infect. Dis. 3:6269.
213. Tsai, T. F., 1997. Coltivirus Colorado tick fever, p. 12091211. In S. S. Long,, L. K. Pickering,, and C. G. Prober (ed.), Principles and Practice of Pediatric Infectious Diseases. Churchill Livingstone, New York, N.Y..
214. Tsai, T. E.,, and T. P. Monath,. 1997. Alphaviruses, p. 12171255. In D. D. Richman,, R. J. Whitley,, and F. G. Hayden (ed.), Clinical Virology. Churchill Livingstone, New York, N.Y..
215. Tsai, T. E.,, M. A. Canfield,, C. M. Reed,, V. L. Flannery,, K. H. Sullivan,, G. R. Reeve,, R. E. Bailey,, and J. D. Poland. 1988. Epidemiological aspects of a St Louis encephalitis outbreak in Harris County, Texas, 1986. J. Infect. Dis. 157:351356.
216. Tsai, T. F.,, F. Popovici,, C. Cernescu,, G. L. Campbell,, and N. 1. Nedelcu. 1998. West Nile encephalitis epidemic in Southeastern Romania. Lancet 352:767771.
217. Turell, M. J.,, S. M. Presley,, A. M. Gad,, S. E. Cope,, D. J. Dohm,, J. C. Morrill,, and R. R. Arthur. 1996. Vector competence of Egyptian mosquitoes for Rift Valley fever virus. Am. J. Trop. Med. Hyg. 54:136139.
218. Van Velden, D. J. J.,, J. D. Meyer,, J. Olivier,, J. H. S. Gear,, and B. Mcintosh. 1977. Rift Valley fever affecting humans in South Africa. Aclinicopathologicalstudy. S. Afr. Med. J. 51:867871.
219. Vaughn, D. W.,, and C. H. Hoke. 1992. The epidemiology of Japanese encephalitis: prospects for prevention. Epidemiol. Rev. 14:197221.
220. Wasay, M.,, R. Diaz-Arrastia,, R. A. Suss,, S. Kojan,, A. Haq,, D. Burns,, and P. V. Ness. 2000. St. Louis encephalitis. A review of 11 cases in a 1995 Dallas, Tex. epidemic. Arch. Neurol. 57:114118.
221. Weaver, S. C.,, R. Salas,, R. Rico-Hesse,, G. V. Ludwi,, M. S. Oberste,, J. Boshell,, and R. B. Tesh. 1996, Re-emergence of epidemic Venezuelan equine encephalomyelitis in South America. Lancet 348:436440.
222. Webb, H. E., 1975. The arbovirus encephalitides, p. 118. In L. S. Illis (ed.), Viral Diseases of the Nervous System. Bailliere Tindall, London, United Kingdom.
223. Webb, H. E.,, M. Chew-Lim,, S. Jagelman,, S. W. Oaten,, S. Pathak,, A. J. Suckling,, and A. Mackenzie,. 1979. Semliki Forest virus infections in mice as a model for studying acute and chronic central nervous system virus infections in man, p. 369390. In F. C. Rose (ed.), Clinical Neuroimmunology. Blackwell Scientific Publications, Oxford, United Kingdom.
224. Webster, H. D. 1956. Eastern equine encephalomyelitis in Massachusetts. Report of two cases, diagnosed serologically, with complete clinical recovery. N. Engl. J. Med. 255:267270.
225. World Health Organization. 1983, The use of veterinary vaccines for prevention and control of Rift Valley fever: memorandum from a WHO/FAO meeting. Bull. W. H. O. 61:261268.
226. World Health Organization. 1997. Dengue haemorrhagic fever. Diagnosis, Treatment, Prevention and Control, 2nd ed. World Health Organization, Geneva, Switzerland.
227. World Health Organization. 1998. Japanese encephalitis vaccines. WorldHealth Organization Position Paper. Wkly. Epidemiol. Rec. 73:337344.
228. WorldHealthOrganization. 2000. Rift Valley Fever. Fact Sheet Number 207, 14. World Health Organization, Geneva, Switzerland.
229. Wulur, S. H.,, E. Jahja,, D. J. Gubler,, T. S. Sutomenggolo,, and J. S. Saroso. 1978. Encephalopathy associated with dengue infection. Lancet i:449450.
230. Zimmerman, H. M. 1946. The pathology of Japanese B encephalitis. Am. J. Pathol. 22:965975.
231. Zlotnik, I.,, C. E. Smith,, D. P. Grant,, and S. Peacock. 1970. The effect of immunosuppression in viral encephalitis with special reference to cyclophosphamide. Br. J. Exp. Pathol. 51:434439.


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TABLE 11.1

Taxonomic classification of the arboviruses discussed in this chapter

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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TABLE 11.2

Summary of pathological features in various forms of arbovirus encephalitis

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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TABLE 11.3

Epidemiologic features of EEE a

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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TABLE 11.4

Epidemiologic features of WEE a

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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TABLE 11.5

Epidemiologic features of VEE a

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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TABLE 11.6

Epidemiologic features of SLE a

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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TABLE 11.7

Epidemiologic features of WNVE a

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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TABLE 11.8

Epidemiologic features of MVE a

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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TABLE 11.9

Epidemiologic features of JE a

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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TABLE 11.10

Epidemiologic features of dengue fever and DHF, including DSS a

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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TABLE 11.11

Cerebral complications in dengue virus infection

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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TABLE 11.12

Endemic characteristics of La Crosse virus encephalitis of the Cal serogroup a

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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TABLE 11.13

Epidemiologic features of RFV a

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11
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TABLE 11.14

Epidemiologic features of TBE a

Citation: Booss J, Esiri M. 2003. 11 The Arboviruses, p 163-189. In Viral Encephalitis in Humans. ASM Press, Washington, DC. doi: 10.1128/9781555817831.ch11

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