Chapter 20 : Human Immunodeficiency Virus, , , and Species

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Human immunodeficiency virus (HIV) type 1 and 2 (HIV-1 and HIV-2) infections have had a profound impact on morbidity and mortality worldwide. AIDS has evolved from an illness of men who have sex with men and of injection drug users into a large and expanding pandemic of heterosexually transmitted disease affecting men, women, and children across the globe. This chapter concentrates on the interaction between HIV-1, immune suppression and reconstitution, and opportunistic microbes such as , and species.

Citation: Isturiz R, Gotuzzo E. 2002. Human Immunodeficiency Virus, , , and Species, p 389-400. In Brogden K, Guthmiller J (ed), Polymicrobial Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555817947.ch20

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Central Nervous System Diseases
Immune Systems
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1. Alcabes, P.,, A. Munoz,, D. Vlahov,, and G. H. Friedland. 1993. Incubation period of human immunodeficiency virus. Epidemiol. Rev. 15:303318.
2. Alvar, J.,, C. Canavate,, B. Gutierrez-Solar,, M. Jimenez,, F. Laguna,, R. Lopez-Velez,, R. Molina,, and J. Moreno. 1997. Leishmania and human immunodeficiency virus coinfection: the first 10 years. Clin. Microbiol. Rev. 10:298319.
3. Alvar, J.,, B. Gutierrez-Solar,, I. Pachon,, E. Calbacho,, M. Ramirez,, R. Valles,, J. L. Guillen,, C. Canavate,, and C. Amela. 1996. AIDS and Leishmania infantum. New approaches for a new epidemiological problem. Clin. Dermatol. 14:541546.
4. Blumenfeld, W.,, O. McCook,, and J. M. Griffiss. 1991. In vitro aggregation of macrophages around human-derived Pneumocystis carinii. J. Protozool. 38:32S33S.
5. Canessa, A.,, V. Del Bono,, F. Miletich,, and V. Pistoia. 1992. Serum cytokines in toxoplas- mosis: increased levels of interferon-gamma in immunocompetent patients with lymphadenopathy but not in AIDS patients with encephalitis. J. Infect. Dis. 165:11681170.
6. Cao, Y.,, L. Qin,, L. Zhang,, J. Safrit,, and D. D. Ho. 1995. Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection. N. Engl. J. Med. 332:201208.
7. Carpenter, C. C.,, D. A. Cooper,, M. A. Fischl,, J. M. Gatell,, B. G. Gazzard,, S. M. Hammer,, M. S. Hirsch,, D. M. Jacobsen,, D. A. Katzenstein,, J. S. Montaner,, D. D. Richman,, M. S. Saag,, M. Schechter,, R. T. Schooley,, M. A. Thompson,, S. Vella,, P. G. Yeni,, and P. A. Volberding. 2000. Antiretroviral therapy in adults: updated recommendations of the International AIDS Society-USA Panel. JAMA 283:381390.
8. Carpenter, C. C.,, M. A. Fischl,, S. M. Hammer,, M. S. Hirsch,, D. M. Jacobsen,, D. A. Katzenstein,, J. S. Montaner,, D. D. Richman,, M. S. Saag,, R. T. Schooley,, M. A. Thompson,, S. Vella,, P. G. Yeni,, and P. A. Volberding. 1998. Antiretroviral therapy for HIV infection in 1998: updated recommendations of the International AIDS Society-USA Panel. JAMA 280:7886.
9. Carrega, G.,, A. Canessa,, P. Argenta,, M. Cruciani,, and D. Bassetti. 1995. T cell blastogenic responses to Toxoplasma gondii trophozoites among HIV-infected patients. AIDS Res. Hum. Retrovir. 11:741746.
10.Centers for Disease Control and Prevention. 1989. Interpretation and use of the Western blot assay for serodiagnosis of human immunodeficiency virus type 1 infections. Morb. Mortal. Wkly. Rep. 38:17.
11. Chen, W.,, E. A. Havell,, and A. G. Harmsen. 1992. Importance of endogenous tumor necrosis factor alpha and gamma interferon in host resistance against Pneumocystis carinii infection. Infect. Immun. 60:12791284.
12. Chen, W.,, E. A. Havell,, L. L. Moldawer,, K. W. McIntyre,, R. A. Chizzonite,, and A. G. Harmsen. 1992. Interleukin 1: an important mediator of host resistance against Pneumocystis carinii. J. Exp. Med. 176:713718.
13. Cheng, V. C.,, K. Y. Yuen,, W. M. Chan,, S. S. Wong,, E. S. Ma,, and R. M. Chan. 2000. Immunorestitution disease involving the innate and adaptive response. Clin. Infect. Dis. 30:882892.
14. Ciricillo, S. F.,, and M. L. Rosenblum. 1990. Use of CT and MR imaging to distinguish intracranial lesions and to define the need for biopsy in AIDS patients. J. Neurosurg. 73:720724.
15. Clarke, J. R.,, and D. Israel-Biet. 1996. Interactions between opportunistic microorganisms and HIV in the lung. Thorax 51:875877.
16. Clerici, M.,, N. I. Stocks,, R. A. Zajac,, R. N. Boswell,, D. R. Lucey,, C. S. Via,, and G. M. Shearer. 1989. Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virusseropositive patients. Independence of CD4+ cell numbers and clinical staging. J. Clin. Invest. 84:18921899.
17. Cohen, O.,, C. Cicala,, M. Vaccarezza,, and A. S. Fauci,. 2000. The immunology of human immunodeficiency virus infection, p. 13741397. In G. L. Mandell,, J. E. Bennett,, and R. F. Dolin (ed.), Principles and Practice of Infectious Diseases, 5th ed. Churchill Livingstone, Philadelphia, Pa.
18. Condom, M. J.,, B. Clotet,, G. Sirera,, F. Milla,, and M. Foz. 1989. Asymptomatic leishmaniasis in the acquired immunodeficiency syndrome (AIDS). Ann. Intern. Med. 111:767768.
19. Delemarre, F. G.,, A. Stevenhagen,, F. P. Kroon,, M. Y. van Eer,, P. L. Meenhorst,, and R. van Furth. 1995. Reduced toxoplasmastatic activity of monocytes and monocyte-derived macrophages from AIDS patients is mediated via prostaglandin E2. AIDS 9:441445.
20. Delemarre, F. G.,, A. Stevenhagen,, F. P. Kroon,, and R. van Furth. 1998. Reduced toxoplasmastatic activity of monocytes from AIDS patients: a role for granulocyte-macrophage colonystimulating factor. Scand. J. Immunol. 47:163166.
21. Derouin, F.,, L. Gerard,, R. Farinotti,, C. Maslo,, and C. Leport. 1998. Determination of the inhibitory effect on Toxoplasma growth in the serum of AIDS patients during acute therapy for toxoplasmic encephalitis. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 19:5054.
22. Desjeux, P.,, B. Piot,, K. O’Neill,, and J. P. Meert. 2001. Co-infections of leishmania/HIV in south Europe. Med. Trop. 61:187193.
23. Desmonts, G.,, and J. Couvreur. 1974. Toxoplasmosis in pregnancy and its transmission to the fetus. Bull. N. Y. Acad. Med. 50:146159.
24. Elvin, K.,, A. Bjorkman,, N. Heurlin,, B. M. Eriksson,, L. Barkholt,, and E. Linder. 1994. Seroreactivity to Pneumocystis carinii in patients with AIDS versus other immunosuppressed patients. Scand. J. Infect. Dis. 26:3340.
25. Elvin, K.,, C. Lidman,, E. Tynell,, E. Linder,, and A. Bjorkman. 1994. Natural history of asymptomatic and symptomatic Pneumocystis carinii infection in HIV infected patients. Scand. J. Infect. Dis. 26:643651.
26. Ezekowitz, R. A.,, D. J. Williams,, H. Koziel,, M. Y. Armstrong,, A. Warner,, F. F. Richards,, and R. M. Rose. 1991. Uptake of Pneumocystis carinii mediated by the macrophage mannose receptor. Nature 351:155158.
27. Foudrinier, F.,, D. Aubert,, D. Puygauthier- Toubas,, C. Rouger,, I. Beguinot,, P. Halbout,, P. Lemaire,, C. Marx-Chemla,, and J. M. Pinon. 1996. Detection of Toxoplasma gondii in immunodeficient subjects by gene amplification: influence of therapeutics. Scand. J. Infect. Dis. 28:383386.
28. Fournier, S.,, C. Rabian,, C. Alberti,, M. V. Carmagnat,, J. F. Garin,, D. Charron,, F. Derouin,, and J. M. Molina. 2001. Immune recovery under highly active antiretroviral therapy is associated with restoration of lymphocyte proliferation and interferon-gamma production in the presence of Toxoplasma gondii antigens. J. Infect. Dis. 183:15861591.
29. French, M. A.,, and P. Price. 2001. Immune restoration disease in HIV-infected patients after antiretroviral therapy. Clin. Infect. Dis. 32:325326.
30. Frenkel, J. K.,, B. M. Nelson,, and J. Arias- Stella. 1975. Immunosuppression and toxoplasmic encephalitis: clinical and experimental aspects. Hum. Pathol. 6:97111.
31. Greene, W. C. 1991. The molecular biology of human immunodeficiency virus type 1 infection. N. Engl. J. Med. 324:308317.
32. Hagler, D. N.,, G. S. Deepe,, C. L. Pogue,, and P. D. Walzer. 1988. Blastogenic responses to Pneumocystis carinii among patients with human immunodeficiency (HIV) infection. Clin. Exp. Immunol. 74:713.
33. Hanano, R.,, and S. H. Kaufmann. 1998. Immune responses to naturally acquired Pneumocystis carinii in gene disruption mutant mice. Res. Immunol. 149:429435, 514.
34. Hanano, R.,, and S. H. Kaufmann. 1998. Pneumocystis carinii and the immune response in disease. Trends Microbiol. 6:7175.
35. Hanano, R.,, K. Reifenberg,, and S. H. Kaufmann. 1998. Activated pulmonary macrophages are insufficient for resistance against Pneumocystis carinii. Infect. Immun. 66:305314.
36. Helweg-Larsen, J.,, T. L. Benfield,, J. Eugen- Olsen,, J. D. Lundgren,, and B. Lundgren. 1999. Effects of mutations in Pneumocystis carinii dihydropteroate synthase gene on outcome of AIDS-associated P. carinii pneumonia. Lancet 354:13471351.
37. Herwaldt, B. L. 1999. Leishmaniasis. Lancet 354:11911199.
38. Hu, D. J.,, T. J. Dondero,, M. A. Rayfield,, J. R. George,, G. Schochetman,, H. W. Jaffe,, C. C. Luo,, M. L. Kalish,, B. G. Weniger,, C. P. Pau,, C. A. Schable,, and J. W. Curran. 1996. The emerging genetic diversity of HIV. The importance of global surveillance for diagnostics, research, and prevention. JAMA 275: 10216.
39. Jimenez, M. I.,, F. Laguna,, F. de la Torre,, F. Solis,, F. Pratlong,, and J. Alvar. 1995. New Leishmania (Leishmania) infantum zymodemes responsible for visceral leishmaniasis in patients coinfected with HIV in Spain. Trans. R. Soc. Trop. Med. Hyg. 89:33.
40. Kassler, W. J.,, C. Haley,, W. K. Jones,, A. R. Gerber,, E. J. Kennedy,, and J. R. George. 1995. Performance of a rapid, on-site human immunodeficiency virus antibody assay in a public health setting. J. Clin. Microbiol. 33:28992902.
41. Kleinman, S.,, M. P. Busch,, L. Hall,, R. Thomson,, S. Glynn,, D. Gallahan,, H. E. Ownby, and A. E. Williams for the Retrovirus Epidemiology Donor Study. 1998. False-positive HIV-1 test results in a low-risk screening setting of voluntary blood donation. JAMA 280:10801085.
42. Kovacs, J. A.,, J. L. Halpern,, J. C. Swan,, J. Moss,, J. E. Parrillo,, and H. Masur. 1988. Identification of antigens and antibodies specific for Pneumocystis carinii. J. Immunol. 140:20232031.
43. Koziel, H.,, X. Li,, M. Y. Armstrong,, F. F. Richards,, and R. M. Rose. 2000. Alveolar macrophages from human immunodeficiency virus-infected persons demonstrate impaired oxidative burst response to Pneumocystis carinii in vitro. Am. J. Respir. Cell Mol. Biol. 23:452459.
44. Laguna, F.,, J. Garcia-Samaniego,, V. Soriano,, E. Valencia,, C. Redondo,, M. J. Alonso,, and J. M. Gonzalez-Lahoz. 1994. Gastrointestinal leishmaniasis in human immunodeficiency virus-infected patients: report of five cases and review. Clin. Infect. Dis. 19:4853.
45. Lane, H. C.,, H. Masur,, L. C. Edgar,, G. Whalen,, A. H. Rook,, and A. S. Fauci. 1983. Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome. N. Engl. J. Med. 309:453458.
46. Laursen, A. L.,, and P. L. Andersen. 1998. Low levels of IgG antibodies against Pneumocystis carinii among HIV-infected patients. Scand. J. Infect. Dis. 30:495499.
47. Laursen, A. L.,, J. Rungby,, and P. L. Andersen. 1995. Decreased activation of the respiratory burst in neutrophils from AIDS patients with previous Pneumocystis carinii pneumonia. J. Infect. Dis. 172:497505.
48. Leport, C.,, G. Chene,, P. Morlat,, B. J. Luft,, F. Rousseau,, S. Pueyo,, R. Hafner,, J. Miro,, J. Aubertin,, R. Salamon,, J. L. Vilde, ANRS 005-ACTG 154 Group Members, Agence Nationale de Recherche sur le SIDA, and AIDS Clinical Trial Group. 1996. Pyrimethamine for primary prophylaxis of toxoplasmic encephalitis in patients with human immunodeficiency virus infection: a double-blind, randomized trial. J. Infect. Dis. 173:9197.
49. Levy, R. M.,, C. M. Mills,, J. P. Posin,, S. G. Moore,, M. L. Rosenblum,, and D. E. Bredesen. 1990. The efficacy and clinical impact of brain imaging in neurologically symptomatic AIDS patients: a prospective CT/MRI study. J. Acquir. Immune Defic. Syndr. 3:461471.
50. Limper, A. H. 1995. Adhesive glycoproteins in the pathogenesis of Pneumocystis carinii pneumonia: host defense or microbial offense? J. Lab. Clin. Med. 125:1213.
51. Luft, B. J.,, and J. S. Remington. 1992. Toxoplasmic encephalitis in AIDS. Clin. Infect. Dis. 15:211222.
52. Macatonia, S. E.,, R. Lau,, S. Patterson,, A. J. Pinching,, and S. C. Knight. 1990. Dendritic cell infection, depletion and dysfunction in HIVinfected individuals. Immunology 71:3845.
53. Mary, C.,, D. Lamouroux,, S. Dunan,, and M. Quilici. 1992. Western blot analysis of antibodies to Leishmania infantum antigens: potential of the 14-kD and 16-kD antigens for diagnosis and epidemiologic purposes. Am. J. Trop. Med. Hyg. 47:764771.
54. Masur, H., 2000. Management of opportunistic infections associated with human immunodeficiency virus infection, p. 15001519. In G. L. Mandell,, J. E. Bennett,, and R. F. Dolin (ed.),Principles and Practice of Infectious Diseases, 5th ed. Churchill Livingstone, Philadelphia, Pa..
55. Matsumoto, Y.,, and Y. Yoshida. 1984. Sporogony in Pneumocystis carinii: synaptonemal complexes and meiotic nuclear divisions observed in precysts. J. Protozool. 31:420428.
56. Meshnick, S. R. 1999. Drug-resistant Pneumocystis carinii. Lancet 354:13181319.
57. Meyer, L.,, M. Magierowska,, J. B. Hubert,, C. Rouzioux,, C. Deveau,, F. Sanson,, P. Debre,, J. F. Delfraissy,, I. Theodorou, and the SEROCO Study Group. 1997. Early protective effect of CCR-5 delta 32 heterozygosity on HIV-1 disease progression: relationship with viral load. AIDS 11:F73F78.
58. Minkoff, H.,, J. S. Remington,, S. Holman,, R. Ramirez,, S. Goodwin,, and S. Landesman. 1997. Vertical transmission of toxoplasma by human immunodeficiency virus-infected women. Am. J. Obstet. Gynecol. 176:555559.
59. Montoya, J. G.,, and J. S. Remington,. 2000. Toxoplasma gondii, p. 28582888. In G. L. Mandell,, J. E. Bennett,, and R. F. Dolin (ed.), Principles and Practice of Infectious Diseases, 5th ed. Churchill Livingstone, Philadelphia, Pa.
60. Murray, H. W.,, B. Y. Rubin,, H. Masur,, and R. B. Roberts. 1984. Impaired production of lymphokines and immune (gamma) interferon in the acquired immunodeficiency syndrome. N. Engl. J. Med. 310:883889.
61. Murray, H. W.,, K. Welte,, J. L. Jacobs,, B. Y. Rubin,, R. Mertelsmann,, and R. B. Roberts. 1985. Production of and in vitro response to interleukin 2 in the acquired immunodeficiency syndrome. J. Clin. Investig. 76:19591964.
62. Narasimhan, S.,, M. Y. Armstrong,, K. Rhee,, J. C. Edman,, F. F. Richards,, and E. Spicer. 1994. Gene for an extracellular matrix receptor protein from Pneumocystis carinii. Proc. Natl. Acad. Sci. USA 91:74407444.
63. Navia, B. A.,, C. K. Petito,, J. W. Gold,, E. S. Cho,, B. D. Jordan,, and R. W. Price. 1986. Cerebral toxoplasmosis complicating the acquired immune deficiency syndrome: clinical and neuropathological findings in 27 patients. Ann. Neurol. 19:224238.
64. Nebuloni, M.,, A. Pellegrinelli,, A. Ferri,, A. Tosoni,, S. Bonetto,, P. Zerbi,, R. Boldorini,, L. Vago,, and G. Costanzi. 2000. Etiology of microglial nodules in brains of patients with acquired immunodeficiency syndrome. J. Neurovirol. 6:4650.
65. Palella, F. J., Jr.,, K. M. Delaney,, A. C. Moorman,, M. O. Loveless,, J. Fuhrer,, G. A. Satten,, D. J. Aschman,, S. D. Holmberg, and the HIV Outpatient Study Investigators. 1998. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N. Engl. J. Med. 338:853860.
66. Pantaleo, G.,, S. Menzo,, M. Vaccarezza,, C. Graziosi,, O. J. Cohen,, J. F. Demarest,, D. Monteflori,, J. M. Orenstein,, C. Fox,, L. K. Schrager, et al. 1995. Studies in subjects with long-term nonprogressive human immunodeficiency virus infection. N. Engl. J. Med. 332:209216.
67. Pavesio, C. E.,, M. L. Chiappino,, P. Y. Setzer,, and B. A. Nichols. 1992. Toxoplasma gondii: differentiation and death of bradyzoites. Parasitol. Res. 78:19.
68. Peglow, S. L.,, A. G. Smulian,, M. J. Linke,, C. L. Pogue,, S. Nurre,, J. Crisler,, J. Phair,, J. W. Gold,, D. Armstrong,, and P. D. Walzer. 1990. Serologic responses to Pneumocystis carinii antigens in health and disease. J. Infect. Dis. 161:296306.
69. Piarroux, R.,, F. Gambarelli,, H. Dumon,, M. Fontes,, S. Dunan,, C. Mary,, B. Toga,, and M. Quilici. 1994. Comparison of PCR with direct examination of bone marrow aspiration, myeloculture, and serology for diagnosis of visceral leishmaniasis in immunocompromised patients. J. Clin. Microbiol. 32:746749.
70. Pierce, M. A.,, M. D. Johnson,, R. J. Maciunas,, M. J. Murray,, G. S. Allen,, M. A. Harbison,, J. L. Creasy,, and R. M. Kessler. 1995. Evaluating contrast-enhancing brain lesions in patients with AIDS by using positron emission tomography. Ann. Intern. Med. 123:594598.
71. Pifer, L. L.,, H. B. Niell,, S. B. Langdon,, S. Baltz,, S. T. Clark,, C. C. Edwards,, and D. R. Woods. 1987. Evidence for depressed humoral immunity to Pneumocystis carinii in homosexual males, commercial plasma donors, and patients with acquired immunodeficiency syndrome. J. Clin. Microbiol. 25:991995.
72. Pifer, L. W.,, B. L. Wolf,, J. J. Weems, Jr.,, D. R. Woods,, C. C. Edwards,, and R. E. Joyner. 1988. Pneumocystis carinii antigenemia in acquired immunodeficiency syndrome. J. Clin. Microbiol. 26:13571361.
73. Porter, S. B.,, and M. A. Sande. 1992. Toxoplasmosis of the central nervous system in the acquired immunodeficiency syndrome. N. Engl. J. Med. 327:16431648.
74. Pratlong, F.,, J. P. Dedet,, P. Marty,, M. Portus,, M. Deniau,, J. Dereure,, P. Abranches,, J. Reynes,, A. Martini,, M. Lefebvre, et al. 1995. Leishmania-human immunodeficiency virus coinfection in the Mediterranean basin: isoenzymatic characterization of 100 isolates of the Leishmania infantum complex. J. Infect. Dis. 172:323326.
75. Remington, J. S.,, R. McLeod,, and G. Desmonts,. 1995. Toxoplasmosis, p. 140266. In J. S. Remington, and J. O. Klein (ed.), Infectious Diseases of the Fetus and Newborn Infants. W. B. Saunders, Philadelphia, Pa.
76. Sherer, R. 1998. Adherence and antiretroviral therapy in injection drug users. JAMA 280:567568.
77. Simon, F.,, P. Mauclere,, P. Roques,, I. Loussert-Ajaka,, M. C. Muller-Trutwin,, S. Saragosti,, M. C. Georges-Courbot,, F. Barre-Sinoussi,, and F. Brun-Vezinet. 1998. Identification of a new human immunodeficiency virus type 1 distinct from group M and group O. Nat. Med. 4:10321037.
78. Sinibaldi, J.,, and I. De Ramirez. 1992. Incidence of congenital toxoplasmosis in live Guatemalan newborns. Eur. J. Epidemiol. 8:516520.
79. Skiest, D. J.,, W. Erdman,, W. E. Chang,, O. K. Oz,, A. Ware,, and J. Fleckenstein. 2000. SPECT thallium-201 combined with Toxoplasma serology for the presumptive diagnosis of focal central nervous system mass lesions in patients with AIDS. J. Infect. 40:274281.
80. Smulian, A. G.,, M. J. Linke,, M. T. Cushion,, R. P. Baughman,, P. T. Frame,, M. N. Dohn,, M. L. White,, and P. D. Walzer. 1994. Analysis of Pneumocystis carinii organism burden, viability and antigens in bronchoalveolar lavage fluid in AIDS patients with pneumocystosis: correlation with disease severity. AIDS 8:15551562.
81. Smulian, A. G.,, D. W. Sullivan,, M. J. Linke,, N. A. Halsey,, T. C. Quinn,, A. P. MacPhail,, M. A. Hernandez-Avila,, S. T. Hong,, and P. D. Walzer. 1993. Geographic variation in the humoral response to Pneumocystis carinii. J. Infect. Dis. 167:12431247.
82. Stephenson, J. 2001. New HIV therapy guidelines. JAMA 285:1281.
83. Subauste, C. S.,, M. Wessendarp,, A. G. Smulian,, and P. T. Frame. 2001. Role of CD40 ligand signaling in defective type 1 cytokine response in human immunodeficiency virus infection. J. Infect. Dis. 183:17221731.
84.UNAIDS and World Health Organization. 1998. AIDS Epidemic Update. UNAIDS, Geneva, Switzerland.
85.UNAIDS and World Health Organization. 2001. AIDS Epidemic Update. UNAIDS, Geneva, Switzerland.
86.UNAIDS and World Health Organization. 1998. Report on the Global HIV/AIDS Epidemic. UNAIDS, Geneva, Switzerland.
87. Walzer, P. D. 1986. Attachment of microbes to host cells: relevance of Pneumocystis carinii. Lab. Invest. 54:589592.
88. Wehle, K.,, M. Schirmer,, J. Dunnebacke- Hinz,, T. Kupper,, and P. Pfitzer. 1993. Quantitative differences in phagocytosis and degradation of Pneumocystis carinii by alveolar macrophages in AIDS and non-HIV patients in vivo. Cytopathology 4:231236.
89. Wolday, D.,, N. Berhe,, H. Akuffo,, and S. Britton. 1999. Leishmania-HIV interaction: immunopathogenic mechanisms. Parasitol. Today 15:182187.
90.World Health Organization. 1995. Report on the Consultative Meeting on leishmaniasis/HIV Coinfection, p. 35. World Health Organization, Rome, Italy .


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Table 1

HIV infection data

Citation: Isturiz R, Gotuzzo E. 2002. Human Immunodeficiency Virus, , , and Species, p 389-400. In Brogden K, Guthmiller J (ed), Polymicrobial Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555817947.ch20

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