Chapter 4 : Basic Bacteriology and Culture

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When a new slow-growing Campylobacter-like organism (CLO) was cultured by Marshall in 1982, it was classified as and shortly after corrected to . During the last decade, the genus has expanded tremendously and new species are regularly included. The majority of these new species are found in the stomachs and intestines of different animals. has occasionally been cultured from ectopic gastric mucosa in Meckel's diverticulum, esophagus, rectum, urinary bladder, dental plaque, and feces. In very young cultures may appear as almost straight rods on microscopy. Detection of from extragastric specimens is carried out by culture and genome methods. Successful cultures have mainly been associated with findings of gastric metaplasia in esophagus, Meckel's diverticulum, and rectum, whereas in one case could not be cultured from the gallbladder with gastric metaplasia. Occasionally, has been cultured from dental plaque and fecal samples. In cell cultures, the initial contact and attachment of to human gastric epithelial cells occur rapidly, often within minutes, at the aflagellated end of the bacterium.

Citation: Anderson L, Wadstrom T. 2001. Basic Bacteriology and Culture, p 27-38. In Mobley H, Mendz G, Hazell S (ed), . ASM Press, Washington, DC. doi: 10.1128/9781555818005.ch4

Key Concept Ranking

Gram-Negative Bacteria
Outer Membrane Proteins
Campylobacter fetus
Campylobacter upsaliensis
Campylobacter fetus
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Table 1

Virulence factors identified in H. pylori

Citation: Anderson L, Wadstrom T. 2001. Basic Bacteriology and Culture, p 27-38. In Mobley H, Mendz G, Hazell S (ed), . ASM Press, Washington, DC. doi: 10.1128/9781555818005.ch4

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