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Persistent Bacterial Infections

Editors: James P. Nataro1, Martin J. Blaser2, Susanna Cunningham-Rundles3
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Affiliations: 1: Center for Vaccine Development and Departments of Pediatrics, Medicine, and Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland; 2: Departments of Medicine and Microbiology, New York University School of Medicine and New York Harbor Veterans Affairs Medical Center, New York, New York; 3: Immunology Research Laboratory, Division of Hermatology and Oncology, Department of Pediatrics, Cornell University Weill Medical College-The New York Presbyterian Hospital, New York, New York
Content Type: Monograph
Format: Hardcover, Electronic
Publication Year: 2000

Category: Bacterial Pathogenesis

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The study of characteristically persistent bacterial infections has begun to focus attention on some of the basic biological questions: How have host and pathogen coevolved to reach the current balance of power? Is persistent colonization and/or infection a biological accident or the result of an evolved equilibrium?

This important new volume, , addresses these and other timely questions. Offering an examination of persistent bacterial infections in the light of ecological and evolutionary principles, it focuses on the principles of parasitism and commensalism and our ability to distinguish the two states. Throughout the volume, the authors explore the ways in which persistent infections differ from acute, self-limiting bacterial infections and how both differ from the nonpathogenic commensal state. The volume also addresses coevolution, host adaptation, natural selection, and other fundamental biological principles.

Valuable reading for investigators and advanced students in the field of bacterial pathogenesis. The volume also includes a foreword by Stanley Falkow.

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