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Virulence Mechanisms of Bacterial Pathogens, Third Edition

Editors: Kim A. Brogden1, James A. Roth2, Thaddeus B. Stanton3, Carole A. Bolin4, F. Chris Minion5, Michael J. Wannemuehler6
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Affiliations: 1: National Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Ames, Iowa; 2: College of Veterinary Medicine, Iowa State University, Ames, Iowa; 3: National Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Ames, Iowa; 4: National Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Ames, Iowa; 5: National Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Ames, Iowa; 6: College of Veterinary Medicine, Iowa State University, Ames, Iowa
Content Type: Monograph
Format: Hardcover
Publication Year: 2000

Category: Bacterial Pathogenesis

MyBook is a cheap paperback edition of the original book and will be sold at uniform, low price.

The field of microbial pathogenesis has expanded rapidly over the past decade. Literally thousands of research papers have been published and new specialty journals on microbial pathogenesis have appeared, giving rise to the need for a text that reviews the entire field of bacterial virulence mechanisms and summarizes the major advances.

The third edition of this best-selling volume provides an overview of current knowledge of the wide variety of mechanisms used by bacterial pathogens in establishing infection, producing disease, and persisting in the host. Internationally recognized authorities in the field review bacterial invasion, colonization, and survival; bacterial evasion of host defense mechanisms; bacterial effects on host cell function; and identification, regulation, and transfer of virulence genes. The final chapter presents an interesting examination of new methods for studying virulence mechanisms in the complex in vivo environment, a major development in studies of bacterial pathogenicity. The overall emphasis is on understanding the mechanisms of host-pathogen interactions rather than on focusing on specific research approaches.

is valuable reading for molecular biologists, infectious disease specialists, researchers, industry scientists, faculty, and graduate students.

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Doody Enterprises_Virulence Mechanisms of Bacterial Pathogens, 4th Edition

20 February 2013

At A Glance

The third edition of this best-selling volume provides an overview of current knowledge of the wide variety of mechanisms used by bacterial pathogens in establishing infection, producing disease, and persisting in the host.

Internationally recognized authorities in the field review bacterial invasion, colonization, and survival; bacterial evasion of host defense mechanisms; bacterial effects on host cell function; and identification, regulation, and transfer of virulence genes. The final chapter presents an interesting amination of new methods for studying virulence mechanisms in the complex in vivo environment, a major development in studies of bacterial pathogenicity. The overall emphasis is on understanding the mechanisms of host-pathogen interactions rather than on focusing on specific research approaches.

Description

The increase in technology has allowed researchers the ability to evaluate pathogenicity of bacteria using newer methods with the hope that this information will lead to new diagnostic tests and drugs to prevent and treat these infectious diseases. This book is a compilation of chapters on topics in bacterial pathogenicity.

Purpose

The editor states that the purpose is to provide a "source of information on the virulence mechanisms of bacterial pathogens." Due to the rapid advances that have occurred since the last edition, this edition is necessary to add the current information needed to move the scientific research ahead.

Audience

This is an appropriate reference for researchers in bacterial pathogenicity as well as a textbook for graduate students in this field. The authors are all published experts in the field of bacterial pathogenicity.

Features

More than 35 authors write the 22 chapters. These chapters review research on at least eight different bacterial pathogens as well as the effect of normal bacterial flora on disease progression. A unique chapter on the commensal bacteria and the effect of this bacterial population on disease shows evidence that the products of bacterial metabolism have a great impact on other normal bacterial flora. It is interesting that the diets of the mammalian host in which bacteria are found in large numbers in the gastrointestinal tract affect this metabolism. These bacterial by-products then affect the host cells as well as the neighboring bacterial cells. It is an interesting thought that normal bacterial flora may be a key to reventing disease. Other chapters provide up-to-date information on mechanisms of pathogenicity as well as host responses.

Assessment

This would be a good textbook for a graduate course to study the various mechanisms by which bacteria cause disease. This is a solid new review of various virulence mechanisms used by bacteria.

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Reviewer: Rebecca Horvat, PhD, D(ABMM) (University of Kansas Medical Center)

Review Date: Unknown

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