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Chapter 14 : Evolution of a Clinical Microbiologist

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Evolution of a Clinical Microbiologist, Page 1 of 2

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Abstract:

In this chapter the author talks about her doctoral research that involved studying interactions of with phagocytes in vitro. The aim of this work was to study the cellular immune response to salmonellae, first by using mouse cells and then moving on to a human system. At that time, knowledge of the intricacies and complexities of the immune system was rudimentary, and the author's work did not clarify the inconsistencies already present in the literature regarding the intracellular fate of microorganisms. Early on, several clinical microbiologists began to assess critically microbiological procedures that either were already in place or coming into use. They also championed the publication of journals and manuals specifically devoted to this discipline. The areas in which the author was especially interested were blood culture instruments and automated and nonautomated rapid identification systems, especially for blood culture isolates and anaerobes. These types of studies were important for determining which systems were accurate, cost-effective, and easily integrated into the work flow of the laboratory. Clearly, the field of clinical microbiology is undergoing changes that could not have been foreseen when the author first entered it. The author expects that like the forerunners who were active in the early days of her career, the new generation of clinical microbiologists will find ways to meet the challenges and bring further regard and advancement to this discipline.

Citation: Morello J. 2000. Evolution of a Clinical Microbiologist, p 101-106. In Atlas R (ed), Many Faces, Many Microbes. ASM Press, Washington, DC. doi: 10.1128/9781555818128.ch14

Key Concept Ranking

Neisseria gonorrhoeae
0.50603765
Localized Infection
0.46522817
Immune Response
0.44815803
Infectious Diseases
0.42394915
0.50603765
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Citation: Morello J. 2000. Evolution of a Clinical Microbiologist, p 101-106. In Atlas R (ed), Many Faces, Many Microbes. ASM Press, Washington, DC. doi: 10.1128/9781555818128.ch14
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References

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1. Morello, J. A. 1999. Clinical Microbiology Reviews: Genesis of a journal. Clin. Microbiol. Rev. 12:183186.
2. Morello, J. A.,, C. Leitch,, S. Nitz,, J. W. Dyke,, M. Andruszewski,, G. Maier,, W. Landau,, and M. A. Beard. 1994. Bacteremia detection by the ESP blood culture system. J. Clin. Microbiol. 32:811818.
3. Morello, J. A.,, S. M. Matushek,, W. M. Dunne,, and D. B. Hinds. 1991 Performance of a BACTEC nonradiometric medium for pediatric blood cultures. J. Clin. Microbiol. 29:359362.
4. Sahm, D.,, S. Boonlayangoor,, and J. A. Morello. 1987. Direct susceptibility testing of blood culture isolates with the AutoMicrobic System (AMS). Diagn. Microbiol. Infect. Dis. 8:111.
5. Janda, W. M.,, J. A. Morello,, S. A. Lerner,, and M. Bohnhoff. 1983. Characteristics of pathogenic Neisseria spp. isolated from homosexual men. J. Clin. Microbiol. 17:8591.
6. Morello, J. A.,, S. A. Lerner,, and M. Bohnhoff. 1976. Characteristics of atypical Neisseria gonorrhoeae from disseminated and localized infections. Infect. Immun. 13:15101516.
7. Morello, J. A.,, and P. D. Ellner. 1969. New medium for blood cultures. Appl. Microbiol. 17:6870.
8. Morello, J. A.,, and E. E. Baker. 1965. Interaction of Salmonella with phagocytes in vitro. J. Infect. Dis. 115:131141.
9. Morello, J. A.,, T. A. DiGenio,, and E. E. Baker. 1964. Evaluation of serological and cultural methods for the diagnosis of chronic salmonellosis in mice J. Bacteriol. 88:12771282.

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