Chapter 11 : Chlamydial Infection

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Perinatal transmission of is a frequent occurrence and is the most clearly defined adverse outcome of chlamydial infections during pregnancy. The objective of this communication is to assess available information on other possible adverse outcomes of chlamydial infection in pregnancy. infection may cause urethritis, cervicitis, endometritis, or salpingitis, and these may be either clinically apparent or subclinical. Chlamydial endometritis has been characterized as a plasma cell endometritis because of infiltration of the endometrium with plasma cells. This association of chlamydial infection with inflammatory infiltrates in the endometrium raises the possibility that such infections are associated with failure of implantation or early pregnancy loss due to spontaneous abortion. Amoxicillin renders women culture negative and prevents transmission to their infants. The immune response appears to play a significant role in the pathogenesis of ocular trachoma and in Chlamydia-associated tubal infertility and ectopic pregnancy.

Citation: Jones R. 1999. Chlamydial Infection, p 195-208. In Hitchcock P, MacKay H, Wasserheit J, Binder R (ed), Sexually Transmitted Diseases and Adverse Outcomes of Pregnancy. ASM Press, Washington, DC. doi: 10.1128/9781555818210.ch11
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Table 1

Association of adverse pregnancy outcomes with maternal infection

Citation: Jones R. 1999. Chlamydial Infection, p 195-208. In Hitchcock P, MacKay H, Wasserheit J, Binder R (ed), Sexually Transmitted Diseases and Adverse Outcomes of Pregnancy. ASM Press, Washington, DC. doi: 10.1128/9781555818210.ch11
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Table 2

Evaluation of treatment and adverse outcome

Citation: Jones R. 1999. Chlamydial Infection, p 195-208. In Hitchcock P, MacKay H, Wasserheit J, Binder R (ed), Sexually Transmitted Diseases and Adverse Outcomes of Pregnancy. ASM Press, Washington, DC. doi: 10.1128/9781555818210.ch11
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Table 3

Results of pregnancy treatment trial

Citation: Jones R. 1999. Chlamydial Infection, p 195-208. In Hitchcock P, MacKay H, Wasserheit J, Binder R (ed), Sexually Transmitted Diseases and Adverse Outcomes of Pregnancy. ASM Press, Washington, DC. doi: 10.1128/9781555818210.ch11

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