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Chapter 19 : Consolidation and Transition

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Consolidation and Transition, Page 1 of 2

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Abstract:

Koch's discovery provided the basis for the field of cellular immunology and Behring and Kitasato's for that of humoral immunology. It is amazing to consider that both these discoveries were made in nearby laboratories in the same building on Klosterstrasse. Lister alluded to this work in the report on his visit to Koch's laboratory in the fall of 1890. Although this work was all done in Koch's institute, much of it was privately financed by Behring himself, including the purchase of the animals needed for the in vivo experiments. This work was so clear and convincing that it became the basis for regulations prepared by a government commission in which Koch participated. These regulations required the bacteriological examination of all public water supplies in Germany which used surface water, and prescribed exactly how the filters should be evaluated. It is of interest that Koch had wanted to leave work on hygiene to return to infectious disease, but he was barely established in his new institute before he was involved in one of the most important hygiene issues of the day. This work was done by Koch's assistants Fred Neufeld and August von Wassermann in goats, donkeys, and cattle, testing for the success of the immunization by subsequently injecting virulent tubercle bacilli. The details of this work are of little current scientific interest, but resulted in strained relationships between Behring and Koch for the rest of Koch's life.

Citation: Brock T. 1999. Consolidation and Transition, p 214-236. In Robert Koch. ASM Press, Washington, DC. doi: 10.1128/9781555818272.ch19

Key Concept Ranking

Bacterial Diseases
0.9336394
Infectious Diseases
0.91169256
Antibacterial Agents
0.8712534
Surface Water
0.6294386
Bacillus anthracis
0.546264
0.9336394
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Figure 19.1

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Citation: Brock T. 1999. Consolidation and Transition, p 214-236. In Robert Koch. ASM Press, Washington, DC. doi: 10.1128/9781555818272.ch19
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Citation: Brock T. 1999. Consolidation and Transition, p 214-236. In Robert Koch. ASM Press, Washington, DC. doi: 10.1128/9781555818272.ch19
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Citation: Brock T. 1999. Consolidation and Transition, p 214-236. In Robert Koch. ASM Press, Washington, DC. doi: 10.1128/9781555818272.ch19
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Citation: Brock T. 1999. Consolidation and Transition, p 214-236. In Robert Koch. ASM Press, Washington, DC. doi: 10.1128/9781555818272.ch19
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Citation: Brock T. 1999. Consolidation and Transition, p 214-236. In Robert Koch. ASM Press, Washington, DC. doi: 10.1128/9781555818272.ch19
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Citation: Brock T. 1999. Consolidation and Transition, p 214-236. In Robert Koch. ASM Press, Washington, DC. doi: 10.1128/9781555818272.ch19
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Citation: Brock T. 1999. Consolidation and Transition, p 214-236. In Robert Koch. ASM Press, Washington, DC. doi: 10.1128/9781555818272.ch19
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