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Structural Biology of Bacterial Pathogenesis

Editors: Gabriel Waksman1, Michael Caparon2, Scott Hultgren3
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Affiliations: 1: Institute of Structural Molecular Biology, Birkbeck College and University College London, London, United Kingdom; 2: Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri; 3: Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri
Content Type: Monograph
Format: Hardcover, Electronic
Publication Year: 2005

Category: Microbial Genetics and Molecular Biology; Bacterial Pathogenesis

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Recent technological advances have led to an outpouring of knowledge in the field of structural biology, yielding an abundance of informational resources available to researchers in the study of bacterial pathogenesis. explores recent developments in the understanding of the molecular basis of bacterial infectious diseases, from structures involved in adhesion and host recognition to those describing elements of bacterial secretion systems. The first compilation of its kind, this new volume offers a convenient review of current research that will engage instructors, students, and professionals in the fields of bacterial pathogenesis and infectious diseases.

Replete with unique illustrations and written by experts, provides a foundation for understanding the molecular interactions required for infection to occur. Readers will gain insight into the role structures play both in our comprehension of pathological processes and in the design of novel antibiotic compounds. Chapters address diverse topics, including host receptors of bacterial origin, sortase pathways in gram-positive bacteria, and bacterial secretion machinery. Illustrations emphasize general concepts related to each disease profiled, as well as concepts concerning the infectious agent causing it.

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