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Chapter 9 : The Neglected Tropical Diseases of North America

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Abstract:

Today, the persistence of the neglected tropical diseases (NTDs) in North America, considered one of the world's wealthiest continents, represents a health disparity of astonishing proportions. The major U.S. NTDs include soil-transmitted helminth infections, especially toxocariasis and strongyloidiasis and cysticercosis, the neglected protozoan infections toxoplasmosis and Chagas disease, and the neglected bacterial and viral infections such as dengue. Cysticercosis may be the single leading cause of epilepsy in the southwestern United States, and toxoplasmosis is a major cause of birth defects. The Inuit of the Canadian Arctic and Alaska also suffer from several NTDs, including toxoplasmosis, trichinellosis, and echinococcosis. Several NTDs, including onchocerciasis, soil-transmitted helminth infections, trachoma, and cutaneous leishmaniasis (CL), occur frequently in rural southern Mexico, especially in Chiapas, and Chagas disease is still focally endemic. Schistosomiasis and lymphatic filariasis (LF) remain serious endemic NTDs in the Caribbean. Many of these NTDs could be easily controlled or eliminated and at relatively modest cost. The most immediate need is to support studies in order to better assess the true prevalence of these infections and then to identify simple and cost-effective public health solutions.

Citation: Hotez P. 2013. The Neglected Tropical Diseases of North America, p 165-187. In Forgotten People Forgotten Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555818753.ch9

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Parasitic Diseases
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West nile virus
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Figures

Image of Figure 9.1
Figure 9.1

Life cycle of human infection with . (From Public Health Image Library, CDC [http://phil.cdc.gov].)

Citation: Hotez P. 2013. The Neglected Tropical Diseases of North America, p 165-187. In Forgotten People Forgotten Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555818753.ch9
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Image of Figure 9.2
Figure 9.2

Life cycle of and cysticercosis. (From Public Health Image Library, CDC [http://phil.cdc.gov].)

Citation: Hotez P. 2013. The Neglected Tropical Diseases of North America, p 165-187. In Forgotten People Forgotten Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555818753.ch9
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Image of Figure 9.3
Figure 9.3

Life cycle of . (From Public Health Image Library, CDC [http://phil.cdc.gov].)

Citation: Hotez P. 2013. The Neglected Tropical Diseases of North America, p 165-187. In Forgotten People Forgotten Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555818753.ch9
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Image of Figure 9.4
Figure 9.4

WNV, diagnosed cases and attack rate, 2012. Numbers within states are the actual number of cases diagnosed; total cases, 5,064. (Data are from www.cdc.gov/ncidod/dvbid/westnile/surv&controlCaseCount12_detailed.htm as of November 6, 2012.)

Citation: Hotez P. 2013. The Neglected Tropical Diseases of North America, p 165-187. In Forgotten People Forgotten Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555818753.ch9
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References

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1. Andrade-Narváez FJ ,, Vargas-González A ,, Canto-Lara SB ,, Damián-Centeno AG . 2001. Clinical picture of cutaneous leishmaniasis due to Leishmania (Leishmania) mexicana in the Yucatan peninsula. Mem Inst Oswaldo Cruz 96:163167.
2. Arnold JH . 1949. The public health problems of hookworm disease in South Carolina. J S C Med Assoc 45:367369.
3. Attaran A . 2006. Chagas disease in Mexico. Lancet 368:1768.
4. Bello M . 2012. More than 1.4 million families live on $2 a day per person. USA Today 2012(February 23). http://usatoday30.usatoday.com/news/nation/story/2012-02-23/extreme-poverty-increase/53227386/1.
5. Bern C ,, Kjos S ,, Yabsley MJ ,, Montgomery SP . 2011. Trypanosoma cruzi and Chagas’ disease in the United States. Clin Microbiol Rev 24:655681.
6. Bleakley H . 2007. Disease and development:evidence from hookworm eradication in the American South. Q J Econ 122:73112.
7. Boston D . 2008. Poverty rates in Texas. Suite101. July 20, 2008. http://suite101.com/ article/poverty-in-texas-a61136.
8. Bouri N ,, Sell TK ,, Franco C ,, Adalja AA ,, Henderson DA ,, Hynes NA . 2012. Return of epidemic dengue in the United States:implications for the public health practitioner. Public Health Rep 127:259266.
9. Brentlinger PE ,, Capps L ,, Denson M . 2003. Hookworm infection and anemia in adult women in rural Chiapas, Mexico. Salud Publica Mex 45:117119.
10. Brunkard JM ,, Robles López JL ,, Ramirez J ,, Cifuentes E ,, Rothenberg SJ ,, Hunsperger EA ,, Moore CG ,, Brussolo RM ,, Villarreal NA ,, Haddad BM . 2007. Dengue fever seroprevalence and risk factors, Texas-Mexico border, 2004. Emerg Infect Dis 13:14771483.
11. Buekens P ,, Almendares O ,, Carlier Y ,, Dumonteil E ,, Eberhard M ,, Gamboa-Leon R ,, James M ,, Padilla N ,, Wesson D ,, Xiong X . 2008. Mother-to- child transmission of Chagas’ disease in North America:why don’t we do more? Matern Child Health J 12:283286.
12. Buijs J ,, Borsboom G ,, Renting M ,, Hilgersom WJ ,, van Wieringen JC ,, Jansen G ,, Neijens J . 1997. Relationship between allergic manifestations and Toxocara seropositivity:a cross-sectional study among elementary school children. Eur Respir J 10:14671475.
13. Busse WW ,, Mitchell H . 2007. Addressing issues of asthma in inner-city children. J Allergy Clin Immunol 119:4349.
14. Centers for Disease Control and Prevention. 2002. Cancer death rates—Appalachia, 1994–1998. MMWR Morb Mortal Wkly Rep 51:527529.
15. Chitsulo L ,, Engels D ,, Montresor A ,, Savioli L . 2000. The global status of schistosomiasis and its control. Acta Trop 77:4151.
16. Chorazy ML ,, Richardson DJ . 2005. A survey of environmental contamination with ascarid ova, Wallingford, Connecticut. Vector Borne Zoonotic Dis 5:3339.
17. DeGiorgio C ,, Pietsch-Escueta S ,, Tsang V ,, Corral-Leyva G ,, Ng L ,, Medina MT ,, Astudillo S ,, Padilla N ,, Leyva P ,, Martinez L ,, Noh J ,, Levine M ,, del Villasenor R ,, Sorvillo F . 2005a. Sero-prevalence of Taenia solium cysticercosis and Taenia solium taeniasis in California, USA. Acta Neurol Scand 111:8488.
18. DeGiorgio CM ,, Sorvillo F ,, Pietsch Escueta S . 2005b. Neurocysticercosis in the United Status:review of an important emerging infection. Neurology 64:1486.
19. del la Garza Y ,, Graviss EA ,, Daver NG ,, Gambarin KJ ,, Shandera WX ,, Schantz PM ,, White Jr. AC 2005. Epidemiology of neurocysticercosis in Houston, Texas. Am J Trop Med Hyg 73:766770.
20. Disalvo AF ,, Melonas J . 1970. Intestinal parasites in South Carolina, 1969. J S C Med Assoc 66:355358.
21. Ehrenberg JP . 2002. An Epidemiological Overview of Geohelminth and Schistosomiasis in the Caribbean. Pan American Health Organization, Washington, DC.
22. Enserink M . 2000. Infectious diseases. Has leishmaniasis become endemic in the U.S.? Science 290:18811883.
23. Farmer HF . 1983. The germ of laziness:a Florida historical perspective. J Fla Med Assoc 70:659662.
24. Flisser A ,, Velasco-Villa A ,, Martínez-Campos C ,, González-Domínguez F ,, Briseño-García B ,, García-Suárez R ,, Caballero-Servín A ,, Hernández-Monroy I ,, García-Lozano H ,, Gutiérrez-Cogco L ,, Rodríguez-Angeles G ,, López-Martínez I ,, Galindo-Virgen S ,, Vázquez-Campuzano R ,, Balandrano-Campos S ,, Guzmán-Bracho C ,, Olivo-Díaz A ,, de la Rosa J ,, Magos C ,, Escobar-Gutiérrez A ,, Correa D . 2002. Infectious diseases in Mexico:a survey from 1995–2000. Arch Med Res 33:343350.
25. Global Programme to Eliminate Lymphatic Filariasis. 2006. Wkly Epidemiol Rec 81:221232.
26. Gubler DJ ,, Reiter P ,, Ebi KL ,, Yap W ,, Nasci R ,, Patz JA . 2001. Climate variability and change in the United States:potential impacts on vector- and rodent-borne diseases. Environ Health Perspect 109(Suppl 2):223233.
27. Hanford EJ ,, Zhan FB ,, Lu Y ,, Giordano A . 2007. Chagas disease in Texas:recognizing the significance and implications of evidence in the literature. Soc Sci Med 65:6079.
28. Healy GR ,, Gleason NN ,, Bokat R ,, Pond H ,, Roper M . 1969. Prevalence of ascariasis and amebiasis in Cherokee Indian school children. Public Health Rep 84:907914.
29. Henderson HE . 1957. Incidence and intensity of hookworm infestation in certain East Texas counties with comparison of technics. Tex Rep Biol Med 15:283291.
30. Hermann N ,, Glickman LT ,, Schantz PM ,, Weston MG ,, Domanski LM . 1985. Seroprevalence of zoonotic toxocariasis in the United States:1971–1973. Am J Epidemiol 122:890896.
31. Hillyer GV . 2005. The rise and fall of Bilharzia in Puerto Rico:its centennial 1904– 2004. P R Health Sci J 24:225235.
32. Hotez PJ . 2008a. Holidays in the sun and the Caribbean’s forgotten burden of neglected tropical diseases. PLoS Negl Trop Dis 2:e239.
33. Hotez PJ . 2008b. Neglected infections of poverty in the United States of America. PLoS Negl Trop Dis 2:e256.
34. Hotez PJ . 2010. Neglected infections of poverty among the indigenous peoples of the Arctic. PLoS Negl Trop Dis 4:e606.
35. Hotez PJ ,, Bottazzi ME ,, Dumonteil E ,, Valenzuela JG ,, Kamhawi S ,, Ortega J ,, Rosales SP ,, Cravioto MB ,, Tapia-Conyer R . 2012. Texas and Mexico:sharing a legacy of poverty and neglected tropical diseases. PLOS Negl Trop Dis 6:e1497.
36. Hotez PJ ,, Gurwith M . 2011. Europe’s neglected infections of poverty. Int J Infect Dis 15:e611e619.
37. Hotez PJ ,, Wilkins PP . 2009. Toxocariasis:America’s most common neglected infection of poverty and a helminthiasis of global importance? PLoS Negl Trop Dis 3:e400.
38. Humphreys M . 2001. Malaria:Poverty, Race, and Public Health in the United States. The Johns Hopkins University Press, Baltimore, MD.
39. Jacobson S . 2007. Rare, non-fatal skin disease found in N. Texans. The Dallas Morning News 2007(September 14).
40. Jones JL ,, Kruszon-Moran D ,, Sanders-Lewis K ,, Wilson M . 2007. Toxoplasma gondii infection in the United States, 1999–2004, decline from the prior decade. Am J Trop Med Hyg 77:405410.
41. Kim K . 2006. Time to screen for congenital toxoplasmosis? Clin Infect Dis 42:13951397.
42. Kuk S ,, Özel E ,, O–uztürk H ,, Kirkil G ,, Kaplan M . 2006. Seroprevalence of Toxocara antibodies in patients with adult asthma. South Med J 99:719722.
43. Lammie PJ ,, Lindo JF ,, Secor WE ,, Vasquez J ,, Ault SK ,, Eberhard ML . 2007. Eliminating lymphatic filariasis, onchocerciasis and schistosomiasis from the Americas:breaking a historical legacy of slavery. PLoS Negl Trop Dis 1:e71.
44. Lopez A ,, Dietz VJ ,, Wilson M ,, Navin TR ,, Jones JL . 2000. Preventing congenital toxoplasmosis. MMWR Recomm Rep 49(RR02):5775.
45. Ludlam JA . 1978. Prevalence of trachoma among Navajo Indian children. Am J Optom Physiol Optics 55:116118.
46. MacLean JD ,, Poirier L ,, Gyorkos TW ,, Proulx JF ,, Bourgeault J ,, Corriveau A ,, Illistiuk S ,, Staudt M . 1992. Epidemiologic and serologic definition of primary and secondary trichinosis in the Arctic. J Infect Dis 165:908912.
47. MacLean JD ,, Viallet J ,, Law C ,, Staudt M . 1989. Trichinosis in the Canadian Arctic:report of five outbreaks and a new clinical syndrome. J Infect Dis 160:513520.
48. Maloney DM ,, Maloney JE ,, Dotson D ,, Popov VL ,, Sanchez RL . 2002. Cutaneous leishmaniasis:Texas case diagnosed by electron microscopy. J Am Acad Dermatol 47:614616.
49. Marmor M ,, Glickman L ,, Shofer F ,, Faich LA ,, Rosenberg C ,, Cornblatt B ,, Friedman S . 1987. Toxocara canis infection of children:epidemiologic and neurospychologic findings. Am J Public Health 77:554559.
50. Martin LK . 1972. Hookworm in Georgia. I. Survey of intestinal helminth infections and anemia in rural school children. Am J Trop Med Hyg 31:919929.
51. Martin MG ,, Humphreys ME . 2006. Social consequence of disease in the American South, 1900–World War II. South Med J 99:862864.
52. McDonald JC ,, Gyorkos TW ,, Alberton B ,, MacLean JD ,, Richer G ,, Juranek D . 1990. An outbreak of toxoplasmosis in pregnant women in northern Quebec. J Infect Dis 161:769774.
53. McLeod R ,, Boyer K ,, Karrison T ,, Kasza K ,, Kasza K ,, Swisher C ,, Roizen N ,, Jalbrzikowski J ,, Remington J ,, Heydemann P ,, Noble AG ,, Mets M ,, Holfels E ,, Withers S ,, Latkany P ,, Meier P ; Toxoplasmosis Study Group. 2006. Outcome of treatment for congenital toxoplasmosis, 1981–2004:the National Collaborative Chicago-based, Congenital Toxoplasmosis Study. Clin Infect Dis 42:13831394.
54. Meyer TE ,, Bull LM ,, Cain Holmes K ,, Pascua RF ,, Travassos da Rosa A ,, Gutierrez CR ,, Corbin T ,, Woodward JL ,, Taylor JP ,, Tesh RB ,, Murray KO . 2007. West Nile virus infection among the homeless, Houston, Texas. Emerg Infect Dis 13:15001503.
55. Nair D . 2001. Screening for Strongyloides infection among the institutionalized mentally disabled. J Am Board Fam Pract 14:5153.
56. O’Neal S ,, Noh J ,, Wilkins P ,, Keene W ,, Lambert W ,, Anderson J ,, Compton Luman J ,, Townes J . 2011. Taenia solium tapeworm infection, Oregon, 2006–2009. Emerg Infect Dis 17:10301036.
57. Ong S ,, Talan DA ,, Moran GJ ,, Mower W ,, Newdow M ,, Tsang VC ,, Pinner RW ; EMERGEncy ID NET Study Group. 2002. Neurocysticercosis in radiographically imaged seizure patients in U.S. emergency departments. Emerg Infect Dis 8:608613.
58. Pan American Health Organization/World Health Organization. 2000. Lymphatic Filariasis Elimination in the Americas:First Regional Program Managers Meeting, Dominican Republic, 9–11 August 2000. Pan American Health Organization, Washington, DC. www.paho.org/English/AD/DPC/CD/lymph_filar_report2000.pdf.
59. Proulx JF ,, MacLean JD ,, Gyorkos TW ,, Leclair D ,, Richter AK ,, Serhir B ,, Forbes L ,, Gajadhar AA . 2002. Novel prevention program for trichinellosis in Inuit communities. Clin Infect Dis 34:15081514.
60. Quattrocchi G ,, Nicoletti A ,, Marin B ,, Bruno E ,, Druet-Cabanac M ,, Preux PM . 2012. Toxocariasis and epilepsy:systematic review and meta-analysis. PLOS Negl Trop Dis 6:e1775.
61. Quihui-Cota L ,, Valencia ME ,, Crompton DW ,, Phillips S ,, Hagan P ,, Diaz-Camacho SP ,, Triana Tejas A . 2004. Prevalence and intensity of intestinal parasitic infections in relation to nutritional status in Mexican schoolchildren. Trans R Soc Trop Med Hyg 98:653659.
62. Rausch RL . 2003. Cystic echinococcosis in the Arctic and Sub-Arctic. Parasitology 127:S73S85.
63. Rearwin DT ,, Tang JH ,, Hughes JW . 1997. Causes of blindness among Navajo Indians:an update. J Am Optom Assoc 68:511517.
64. Rebollar-Téllez EA ,, Tun-Ku E ,, Manrique-Saide PC ,, Andrade-Narvaez FJ . 2005. Relative abundances of sandfly species (Diptera:Phlebotominae) in two villages in the same area of Campeche, in southern Mexico. Ann Trop Med Parasitol 99:193201.
65. Reeves WK ,, Murray KO ,, Meyer TE ,, Bull LM ,, Pascua RF ,, Holmes KC ,, Loftis AD . 2008. Serological evidence of typhus group rickettsia in a homeless population in Houston, Texas. J Vector Ecol 33:205207.
66. Robinson P ,, Garza A ,, Weinstock J ,, Serpa JA ,, Goodman JC ,, Eckols KT ,, Firozgary B ,, Tweardy DJ . 2012. Substance P causes seizures in neurocysticercosis. PLOS Pathog 8:e1002489.
67. Sargent RG ,, Dudley BW ,, Fox AS ,, Lease EJ . 1972. Intestinal helminths in coastal South Carolina:a problem in southeastern United States. South Med J 65:294298.
68. Sarkar S ,, Strutz SE ,, Frank DM ,, Rivaldi CL ,, Sissel B ,, Sánchez-Cordero V . 2010. Chagas disease risk in Texas. PLoS Negl Trop Dis 4:e836.
69. Schantz PM ,, Tsang VC . 2003. The US Centers for Disease Control and Prevention (CDC) and research and control of cysticercosis. Acta Trop 87:161163.
70. Serpa JA ,, Graviss EA ,, Kass JS ,, White Jr. AC 2011. Neurocysticercosis in Houston, Texas:an update. Medicine (Baltimore) 90:8186.
71. Sharghi N ,, Schantz PM ,, Caramico L ,, Ballas K ,, Teague BA ,, Hotez PJ . 2001. Environmental exposure to Toxocara as a possible risk factor for asthma:a clinic-based case-control study. Clin Infect Dis 32:e111e116.
72. Sharghi N ,, Schantz P ,, Hotez PJ . 2000. Toxocariasis:an occult cause of childhood neuropsychological deficits and asthma? Semin Pediatr Infect Dis 11:257260.
73. Siddiqui AA ,, Berk SL . 2001. Diagnosis of Strongyloides stercoralis infection. Clin Infect Dis 33:10401047.
74. Sorvillo FJ ,, DeGiorgio C ,, Waterman SH . 2007. Deaths from cysticercosis, United States. Emerg Infect Dis 13:230235.
75. Starr MC ,, Montgomery SP . 2011. Soil-transmitted helminthiasis in the United States:a systematic review—1940–2010. Am J Trop Med 85:680684.
76. Tapia-Conyer R . 2006. Chagas’ disease in Mexico—response from the Mexican Ministry of Health. Lancet 368:17681769.
77. Tapia-Conyer R ,, Betancourt-Cravioto M ,, Méndez-Galván J . 2012. Dengue:an escalating public health problem in Latin America. Paediatr Int Child Health 32(Suppl 1):1417.
78. The Economic Collapse. 2011. Extreme poverty is now at record levels—19 statistics about the poor that will absolutely astound you. The Economic Collapse. November 4, 2011. http://theeconomiccollapseblog.com/archives/extreme-poverty-is-now-at-record-levels-19-statistics-about-the-poor-that-will-absolutely-astound-you.
79. Vinetz JM ,, Glass GE ,, Flexner CE ,, Mueller P ,, Kaslow DC . 1996. Sporadic urban leptospirosis. Ann Intern Med 125:794798.
80. Wallin MT ,, Kurtzke JF . 2004. Neurocysticercosis in the United States:review of an important emerging problem. Neurology 63:15591564.
81. Weina PJ ,, Neafie RC ,, Wortmann G ,, Polhemus M ,, Aronson NE . 2004. Old World leishmaniasis:an emerging infection among deployed US military and civilian workers. Clin Infect Dis 39:16741680.
82. White Jr AC ,, Atmar RL . 2002. Infections in Hispanic immigrants. Clin Infect Dis 34:16271632.
83. Willard RJ ,, Jeffcoat AM ,, Benson PM ,, Walsh DC . 2005. Cutaneous leishmaniasis in soldiers from Fort Campbell, Kentucky returning from Operation Iraqi Freedom highlights diagnostic and therapeutic options. J Am Acad Dermatol 52:977987.
84. Wilson JF ,, Rausch RL ,, Wilson FR . 1995. Alveolar hydatid disease. Ann Surg 221:315323.
85. Won KY ,, Kruszon-Moran D ,, Schantz PM ,, Jones JL . 2008. National seroprevalence and risk factors for zoonotic Toxocara spp. infection. Am J Trop Med Hyg 79:552557.
86. World Health Organization. 2006. Onchocerciasis (river blindness). Report from the fifteenth InterAmerican Conference on Onchocerciasis, Caracas, Venezuela. Wkly Epidemiol Rec 81:293296.
87. Yen H . 2012. U.S. poverty on track to rise to highest since 1960s. Huffington Post. July 22, 2012. www.huffingtonpost.com/2012/07/22/us-poverty-level-1960s_n_1692744.html.

Tables

Generic image for table
Table 9.1

Summary of the NTDs of the United States and the Arctic region

Compiled from ; Proulx et al., 2002; and .

Citation: Hotez P. 2013. The Neglected Tropical Diseases of North America, p 165-187. In Forgotten People Forgotten Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555818753.ch9

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