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Enterohemorrhagic Escherichia coli and Other Shiga Toxin-Producing E. coli
Whether contracted through contaminated food or a trip to the petting zoo, disease-causing E. coli is a major human health threat
Most Escherichia coli strains live harmlessly in the intestines of healthy humans and animals, but virulent strains—the enterohemorrhagic E. coli (EHEC) and certain Shiga toxin–producing E. coli (STEC)—cause life-threatening infections, with young children and the elderly most at risk. EHEC and STEC are easily transmitted through contaminated water or food and, more rarely, through contact between animals and people. Thus, controlling outbreaks of these pathogens is a concern for the infectious disease community and the food industry.
Covering a diverse array of topics, including microbial pathogenesis, disease pathophysiology, food safety, genetic analysis, veterinary microbiology, epidemiology, and environmental microbiology, Enterohemorrhagic Escherichia coli and Other Shiga Toxin-Producing E. coli presents the most current, relevant research overview from a multidisciplinary, international group of expert authors concerned with tracking, deciphering, and dealing with the diseases caused by EHEC and STEC.
Editors Vanessa Sperandio and Carolyn J. Hovde have updated and expanded the scope of the previous edition, Escherichia coli O157:H7 and Other Shiga Toxin-Producing E. coli Strains. Useful as a textbook for advanced courses in microbiology, food safety, infectious disease, or microbial pathogenesis, this new volume is also a valuable reference for research scientists, clinicians, health professionals, policy makers, and food safety professionals.
"This volume, edited by two experts in the field, Vanessa Sperandio and Carolyn Hovde, encompasses the current state of knowledge of the epidemiology and pathogenesis of EHEC and defines the challenges to improved disease control. Comprehensive and timely, this is a must read for those engaged in E. coli research."
– Guy H. Palmer, Regents Professor and Director of the Paul G. Allen School for Global Animal Health, Washington State University, Pullman
Vanessa Sperandio is a Professor in the Departments of Microbiology and Biochemistry at the University of Texas Southwestern Medical Center. Her research investigates chemical, stress, and nutritional signaling at the interface among the mammalian host, beneficial microbiota, and invading pathogens. A fellow of the American Academy of Microbiology and the 2015 recipient of the ASM Eli Lilly and Company-Elanco Research Award, Dr. Sperandio serves on the editorial boards of mBio, Infection and Immunity, Journal of Bacteriology, and Gut Pathogens.
Carolyn J. Hovde is a University Distinguished Professor who has served as the Idaho NIH INBRE Director since 2006. Dr. Hovde’s laboratory studies E. coli O157:H7 with a primary focus on understanding the relationship between this human pathogen and its silent reservoir, healthy cattle. A Fellow of the American Association for the Advancement of Science and winner of the ASM Carski Foundation Distinguished Undergraduate Teaching Award, she is President of the National Association of IDeA Principal Investigators (NAIPI).
Hardcover, 570 pages, full-color illustrations, index.