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Chapter 11.8 : Human Immunodeficiency Virus Serology

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Human Immunodeficiency Virus Serology, Page 1 of 2

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Citation: Leber A. 2016. Human Immunodeficiency Virus Serology, p 11.8.1.1-11.8.2.3. In Clinical Microbiology Procedures Handbook, Fourth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818814.ch11.8
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Figures

Image of Figure 11.8.1–1
Figure 11.8.1–1

Fourth-generation HIV testing algorithm. Reprinted from CDC. 2013. 62:489–494, with permission.

Citation: Leber A. 2016. Human Immunodeficiency Virus Serology, p 11.8.1.1-11.8.2.3. In Clinical Microbiology Procedures Handbook, Fourth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818814.ch11.8
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References

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1. Goodsell DS. 2015. Illustrations of the HIV life cycle. Curr Top Microbiol Immunol 389:243252.
2. McCutchan FE. 2006. Global epidemiology of HIV. J Med Virol 78(Suppl 1):S7S12.
3. Branson B, Mermin J. 2011. Establishing the diagnosis of HIV infection: new tests and a new algorithm for the United States. J Clin Virol 52S:S3S4.
4. Manlutac AL, Giesick JS, McVay PA. 2013. Identification of early HIV infections using the fourth generation Abbott ARCHITECT HIV Ag/Ab Combo chemiluminescent microparticle immunoassay (CIA) in San Diego County. J Clin Virol 58(Suppl 1):e44e47.
5. Mitchell EO, Stewart G, Bajzik O, Ferret M, Bentsen C, Shriver MK. 2013. Performance comparison of the 4th generation Bio-Rad Laboratories GS HIV Combo Ag/Ab EIA on the EVOLIS™ automated system versus Abbott ARCHITECT HIV Ag/Ab Combo, Ortho Anti-HIV 1+2 EIA on Vitros ECi and Siemens HIV-1/O/2 enhanced on Advia Centaur. J Clin Virol 58(Suppl 1):e79e84.
6. Masciotra S, Smith AJ, Youngpairoj AS, Sprinkle P, Miles I, Sionean C, Paz-Bailey G, Johnson JA, Owen SM. 2013. Evaluation of the CDC proposed laboratory HIV testing algorithm among men who have sex with men (MSM) from five US metropolitan statistical areas using specimens collected in 2011. J Clin Virol 58(Suppl 1):e8e12.
7. Muthukumar A, Alatoom A, Burns A, Ashmore J, Kim A, Emerson B, Bannister E, Ansari MQ. 2015. Comparison of 4th-generation HIV antigen/antibody combination assay with 3rd generation HIV antibody assays for the occurrence of false positive and false negative results. Lab Med 46:8489.
1. Masciotra S, Smith AJ, Youngpairoj AS, Sprinkle P, Miles I, Sionean C, Paz-Bailey G, Johnson JA, Owen SM. 2013. Evaluation of the CDC proposed laboratory HIV testing algorithm among men who have sex with men (MSM) from five US metropolitan statistical areas using specimens collected in 2011. J Clin Virol 58(Suppl 1):e8e12.
2. Muthukumar A, Alatoom A, Burns A, Ashmore J, Kim A, Emerson B, Bannister E, Ansari MQ. 2015. Comparison of 4th-generation HIV antigen/antibody combination assay with 3rd generation HIV antibody assays for the occurrence of false positive and false negative results. Lab Med 46:8489.
3. Abbate I, Pergola C, Pisciotta M, Sciamanna R, Sias C, Orchi N, Libertone R, Ippolito G, Capobianchi MR. 2014. Evaluation in a clinical setting of the performances of a new rapid confirmatory assay for HIV 1/2 serodiagnosis. J Clin Virol 61:166169.
4. Mor O, Mileguir F, Michaeli M, Levy I, Mendelson E. 2014. Evaluation of the Bio-Rad Geenius HIV 1/2 assay as an alternative to the INNO-LIA HIV 1/2 assay for confirmation of HIV infection. J Clin Microbiol 52:26772679.
5. Malloch L, Kadivar K, Putz J, Levett PN, Tang J, Hatchette TF, Kadkhoda K, Ng D, Ho J, Kim J. 2013. Comparative evaluation of the Bio-Rad Geenius HIV-1/2 confirmatory assay and the Bio-Rad Multispot HIV-1/2 rapid test as an alternative differentiation assay for CLSI M53 algorithm-I. J Clin Virol 58(Suppl 1):e85e91.
6. Duong YT, Mavengere Y, Patel H, Moore C, Manjengwa J, Sibandze D, Rasberry C, Mlambo C, Li Z, Emel L, Bock N, Moore J, Nkambule R, Justman J, Reed J, Bicego G, Ellenberger DL, Nkengasong JN, Parekh BS. 2014. Poor performance of the determine HIV-1/2 Ag/Ab combo fourth-generation rapid test for detection of acute infections in a national household survey in Swaziland. J Clin Microbiol 52:37433748.
7. Cárdenas AM, Baughan E, Hodinka RL. 2013. Evaluation of the Bio-Rad Multispot HIV-1/HIV-2 rapid test as an alternative to Western blot for confirmation of HIV infection. J Clin Virol 58(Suppl 1):e97e103.

Tables

Generic image for table
Table 11.8.1–1

HIV classification scheme

Citation: Leber A. 2016. Human Immunodeficiency Virus Serology, p 11.8.1.1-11.8.2.3. In Clinical Microbiology Procedures Handbook, Fourth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818814.ch11.8
Generic image for table
Table 11.8.1–2

Currently (as of October2015) available FDA-cleared HIV fourth- and fifth-generation and supplemental assays

Citation: Leber A. 2016. Human Immunodeficiency Virus Serology, p 11.8.1.1-11.8.2.3. In Clinical Microbiology Procedures Handbook, Fourth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818814.ch11.8

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