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Chapter 16.2 : Levels of Laboratory Safety

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Levels of Laboratory Safety, Page 1 of 2

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Abstract:

Reported laboratory-acquired infections have been due to a wide variety of microorganisms. The largest survey of infections was reported in 1976 by Pike who found that 4079 laboratory-acquired infections were due to 159 agents, although 10 agents accounted for >50% of the cases (http://cid.oxfordjournals.org/content/49/1/142.full-ref-35). Over 170 known deaths have resulted from laboratory-acquired infections ( ).

Citation: Leber A. 2016. Levels of Laboratory Safety, p 16.2.1-16.2.6. In Clinical Microbiology Procedures Handbook, Fourth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818814.ch16.2
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References

/content/book/10.1128/9781555818814.chap16.2
1. Weinstein R. 2009. Laboratory acquired infections. Clin Infect Dis 49:142147.
2. Baron E-J, Miller M. 2008. Bacterial and fungal infections among diagnostic laboratory workers: evaluating the risks. Diagn Microbiol Infect Dis 60:241246.
3. Pike RM. 1979. Laboratory-associated infections: incidence, fatalities, causes and prevention. Annu Rev Microbiol 33:4146.
4. Pike RM. 1976. Laboratory-associated infections: summary and analysis of 3921 cases. Health Lab Sci 13:105114.
5. Grist NR, Emslie JAN. 1991. Infections in British clinical laboratories, 1988–1989. J Clin Pathol 44:667669.
6. Walker D, Campbell D. 1999. A survey of infections in United Kingdom laboratories, 1994–1995. J Clin Pathol 52:415418
7. U.S. Department of Health and Human Services. 2007. Biosafety in Microbiological and Biomedical Laboratories, 5th ed. U.S. Government Printing Office, Washington, DC.
8. Jamison R, Noble MA, Proctor EM, Smith JA. 1996. Cumitech 29, Laboratory Safety in Clinical Microbiology. Coordinating ed, Smith JA. ASM Press, Washington, DC.
9. Centers for Disease Control and Prevention. 2000. Biological and chemical terrorism: strategic plan for preparedness and response. MMWR Morb Mortal Wkly Rep 49:114.
10. Gilchrist MJR, McKinney WP, Miller JM, Weissfeld AS. 2000. Cumitech 33, Laboratory Safety, Management, and Diagnosis of Agents Associated with Bioterrorism. Coordinating ed, Snyder JW. ASM Press, Washington, DC.
11. Klietman WF, Ruoff KL. 2001. Bioterrorism: implications for the clinical microbiologist. Clin Microbiol Rev 14:364381.

Tables

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Table 16.2–1

Summary of BSL 1

Citation: Leber A. 2016. Levels of Laboratory Safety, p 16.2.1-16.2.6. In Clinical Microbiology Procedures Handbook, Fourth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818814.ch16.2
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Table 16.2–2

Summary of BSL 2

Citation: Leber A. 2016. Levels of Laboratory Safety, p 16.2.1-16.2.6. In Clinical Microbiology Procedures Handbook, Fourth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818814.ch16.2
Generic image for table
Table 16.2–3

Summary of BSL 3

Citation: Leber A. 2016. Levels of Laboratory Safety, p 16.2.1-16.2.6. In Clinical Microbiology Procedures Handbook, Fourth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818814.ch16.2
Generic image for table
Table 16.2–4

Summary of BSL 4

Citation: Leber A. 2016. Levels of Laboratory Safety, p 16.2.1-16.2.6. In Clinical Microbiology Procedures Handbook, Fourth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818814.ch16.2

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