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Chapter 3.2.7 : Airborne Viruses

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Airborne Viruses, Page 1 of 2

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Abstract:

Particles containing infectious human or animal viruses can contaminate air indoors or outdoors. The survival of such airborne viruses is influence by a variety of physical and chemical factors, important among these being temperature and relative humidity. Air currents outdoors can carry surviving viruses over several kilometers and such windborne spread is believed have resulted in outbreaks of animal diseases. Movements of air indoors can also transport viruses within houses and buildings. Indoor air can be decontaminated by filtering out viruses or by inactivating them with chemicals or physical agents such as ultraviolet inrradiation. Recent years have seen a revival of interest in airborne viruses in delivering vaccines, biothreat agents, and to better understand and prevent the spread of emerging/reemerging infections such as influenza.

Citation: Sattar S, Bhardwaj N, Ijaz M. 2016. Airborne Viruses, p 3.2.7-1-3.2.7-24. In Yates M, Nakatsu C, Miller R, Pillai S (ed), Manual of Environmental Microbiology, Fourth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818821.ch3.2.7
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FIGURE 1

Direct or indirect exposure of susceptible hosts to aerosolized viruses. doi:10.1128/9781555818821.ch3.2.7.f1

Citation: Sattar S, Bhardwaj N, Ijaz M. 2016. Airborne Viruses, p 3.2.7-1-3.2.7-24. In Yates M, Nakatsu C, Miller R, Pillai S (ed), Manual of Environmental Microbiology, Fourth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818821.ch3.2.7
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Image of FIGURE 2
FIGURE 2

Scanning electron micrograph of an aerosol particle attached to a strand of spider web. Bar = 0.5 µm. (Reproduced with permission from Dr. B. Kournikakis of the Defence Research Establishment, Suffield, Alberta, Canada.). doi:10.1128/9781555818821.ch3.2.7.f2

Citation: Sattar S, Bhardwaj N, Ijaz M. 2016. Airborne Viruses, p 3.2.7-1-3.2.7-24. In Yates M, Nakatsu C, Miller R, Pillai S (ed), Manual of Environmental Microbiology, Fourth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818821.ch3.2.7
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Image of FIGURE 3
FIGURE 3

Biological decay of NDV captured on a spider web and held under sunlight (a) and under cloudy conditions (b). Control samples were held in the dark. (Reproduced with permission from Dr. B. Kournikakis of the Defence Research Establishment, Suffield, Alberta, Canada.) Expon. = The rate of loss in the viability of the virus. doi:10.1128/9781555818821.ch3.2.7.f3

Citation: Sattar S, Bhardwaj N, Ijaz M. 2016. Airborne Viruses, p 3.2.7-1-3.2.7-24. In Yates M, Nakatsu C, Miller R, Pillai S (ed), Manual of Environmental Microbiology, Fourth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818821.ch3.2.7
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References

/content/book/10.1128/9781555818821.ch3.2.7
1. Sattar SA, Ijaz MK. 1987. Spread of viral infections by aerosols. CRC Crit Rev Environ Control 17:89131.[CrossRef]
2. Whon TW, Kim MS, Roh SW, Shin NR, Lee HW, Bae JW. 2012. Metagenomic characterization of airborne viral DNA diversity in the near-surface atmosphere. J Virol 86:82218231.[PubMed][CrossRef]
3. Posada JA, Redrow J, Celik I. 2010. A mathematical model for predicting the viability of airborne viruses. J Virol Methods 164:8895.[PubMed][CrossRef]
4. Goldmann DA. 2000. Transmission of viral respiratory infections in the home. Pediatr Infect Dis J 19:S97102.[PubMed][CrossRef]
5. Myatt TA, Johnston SL, Rudnick S, Milton DK. 2003. Airborne rhinovirus detection and effect of ultraviolet irradiation on detection by a semi-nested RT-PCR assay. BMC Pub Hlth 3:5.[CrossRef]
6. Myatt TA, Johnston SL, Zuo Z, Wand W, Kebadze T, Rudnick S, Milton DK. 2004. Detection of airborne rhinovirus and its relation to outdoor air supply in office environments. Am J Respir Crit Care Med 169:11871190.[PubMed][CrossRef]
7. Carling PC, Bruno-Murtha LA, Griffiths JK. 2009. Cruise ship environmental hygiene and the risk of norovirus infection outbreaks: an objective assessment of 56 vessels over 3 years. Clin Infect Dis 49:13121317.[PubMed][CrossRef]
8. Gupta S. 2002. Cruising for trouble. Don't blame the ocean liners. You can get this stomach bug almost anywhere. Time 160:86.[PubMed]
9. Christensen LS, Mortensen S, Botner A, Strandbygaard BS, Ronsholt L, Henriksen CA, Andersen JB. 1993. Further evidence of long-distance airborne transmission of Aujeszky disease (pseudorabies) virus. Vet Rec 132:317321.[PubMed][CrossRef]
10. Donaldson AI, Alexandersen S. 2002. Predicting the spread of foot and mouth disease by airborne virus. Rev Sci Tech 21:569575.[PubMed]
11. Gloster J, Champion HJ, Mansley LM, Romero P, Brough T, Ramirez A. 2005. The 2001 epidemic of foot-and-mouth disease in the United Kingdom: epidemiological and meteorological case studies. Vet Rec 156:793803.[PubMed][CrossRef]
12. Maragon S, Facchin E, Moutou F, Massirio I, Vincenzi G, Davies G. 1994. The 1993 Italian foot-and-mouth-disease epidemic—epidemiologic features of the 4 outbreaks identified in Verona Province (Veneto Region). Vet Rec 135:5357.[PubMed][CrossRef]
13. Grant RH, Scheidt AB, Rueff LR. 1994. Aerosol transmission of a viable virus affecting swine: explanation of an epizootic of pseudorabies. Int J Biometeorol 38:3339.[PubMed][CrossRef]
14. Hammond GW, Raddatz RL, Gelskey DE. 1989. Impact of atmospheric dispersion and transport of viral aerosols on the epidemiology of influenza. Rev Infect Dis 11:494497.[PubMed][CrossRef]
15. Gloster J, Jones A, Redington A, Burgin L, Sorensen JH, Turner R, Dillon M, Hullinger P, Simpson M, Astrup P, Garner G, Stewart P, D'Amours R, Sellers R, Paton P. 2010. Airborne spread of foot-and-mouth disease—model intercomparison. Vet J 183:278286.[PubMed][CrossRef]
16. Echavarria M, Kolavic SA, Cersovsky S, Mitchell F, Sanchez JL, Polyak C, Innis BL, Binn LN. 2000. Detection of adenoviruses (AdV) in culture-negative environmental samples by PCR during an AdV-associated respiratory disease outbreak. J Clin Microbiol 38:29822984.[PubMed]
17. Eickhoff TC. 1994. Airborne nosocomial infection—a contemporary perspective. Infect Contr Hosp Epidemiol 15:663672.[CrossRef]
18. Sawyer MH, Chamberlin CJ, Wu YN, Aintablian N, Wallace MR. 1994. Detection of varicella-zoster virus DNA in air samples from hospital rooms. J Infect Dis 169:9194.[PubMed][CrossRef]
19. Garden JM, O'Banion MK, Bakus DA, Olson C. 2002. Viral disease transmitted by laser-generated plume (aerosol). Arch Dermatol 138:13031307.[PubMed][CrossRef]
20. Booth TF, Kournikakis B, Bastien N, Ho J, Kobasa D, Stadnyk L, Li Y, Spence M, Paton S, Henry B, Mederski B, White D, Low DE, McGeer A, Simor A, Vearncombe M, Downey J, Jamieson FB, Tang P, Plummer F. 2005. Detection of airborne severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak units. J Infect Dis 191:14721477.[PubMed][CrossRef]
21. Hietala SK, Hullinger PJ, Crossley BM, Kinde H, Ardans AA. 2005. Environmental air sampling to detect exotic Newcastle disease virus in two California commercial poultry flocks. J Vet Diagn Invest 17:198200.[PubMed][CrossRef]
22. Barry M, Bia F, Cullen M, Dembry L, Fischer S, Geller G, Hierholzer W, Mcphedran P, Rainey P, Russi M, Snyder E, Wrone E, Gonzalez JP, Ricohesse R, Tesh R, Ryder R, Shope R, Quinn WP, Galbraith PD, Cartter ML, Hadler JL, Demaria A. 1994. Arenavirus infection—Connecticut, 1994. J Am Med Assoc 272:998999.[CrossRef]
23. Dewulf J, Laevens H, Koenen F, Mintiens K, de Kruif A. 2000. Airborne transmission of classical swine fever virus under experimental conditions. Vet Rec 147:735738.[PubMed]
24. Marks PJ, Vipond IB, Carlisle D, Deakin D, Fey RE, Caul EO. 2000. Evidence for airborne transmission of Norwalk-like virus (NLV) in a hotel restaurant. Epidemiol Infect 124:481487.[PubMed][CrossRef]
25. Marks PJ, Vipond IB, Regan FM, Wedgwood K, Fey RE, Caul EO. 2003. A school outbreak of Norwalk-like virus: evidence for airborne transmission. Epidemiol Infect 131:727736.[PubMed][CrossRef]
26. Suzuki K, Yoshikawa T, Tomitaka A, Matsunaga K, Asano Y. 2204. Detection of aerosolized varicella-zoster virus DNA in patients with localized herpes zoster. J Infect Dis 189:10091012.[CrossRef]
27. Slote L. 1976. Viral aerosols—a potential occupationally related health threat in aerated wastewater treatment systems. J Environ Hlth 38:310314.
28. National Institute of Standards and Technology Challenges in microbial sampling in the indoor environment workshop summary. Report TN 1737. 2012. U.S. Dept. Commerce. http://www.nist.gov/mml/bbd/biomolecular/upload/Sloan-Roport-Final-TN-1737.pdf.
29. Li KS, Guan Y, Wang J, Smith GJD, Xu KM, Duan L, Rahardjo PA, Puthavathana P, Buranathai C, Nguyen TD, Estoepangestie ATS, Chaisingh A, Auewarakul P, Long HT, Hanh NTH, Webby RJ, Poon LLM, Chen H, Shortridge KF, Yuen KY, Webster RG, Peiris JSM. 2004. Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia. Nature 430:209213.[PubMed][CrossRef]
30. Roy CJ, Milton DK. 2004. Airborne transmission of communicable infection—the elusive pathway. N Engl J Med 350:17101712.[PubMed][CrossRef]
31. Yu IT, Wong TW, Chiu YL, Lee N, Li Y. 2005. Temporal-spatial analysis of severe acute respiratory syndrome among hospital inpatients. Clin Infect Dis 40:12371243.[PubMed][CrossRef]
32. Wan GH, Huang CG, Huang YC, Huang JP, Yang SL, Lin TY, Tsao KC. 2012. Surveillance of airborne adenovirus and Mycoplasma pneumoniae in a hospital pediatric department. PLoS One 7:e33974. doi:10.1371/journal.pone.0033974.[PubMed][CrossRef] http://dx.doi.org/10.1371/journal.pone.0033974
33. Gooze LL, Hughes EC. 2003. Smallpox. Semin Respir Infect 18:196205.[PubMed]
34. Herfst S, Schrauwen EJ, Linster M, Chutinimitkul S, de Wit E, Munster VJ, Sorrell EM, Bestebroer TM, Burke DF, Smith DJ, Rimmelzwaan GF, Osterhaus AD, Fouchier RA. 2012. Airborne transmission of influenza A/H5N1 virus between ferrets. Science 336:15341541.[PubMed][CrossRef]
35. Andersen AA. 1958. New sampler for the collection, sizing, and enumeration of viable airborne particles. J Bacteriol 76:471484.[PubMed]
36. Crook B., 1995. Inertial samplers: biological perspective, p 247267. In Cox CS,, Wathes CM (eds), Bioaerosols handbook. CRC Press, Boca Raton, FL.
37. Crook B., 1995. Non-inertial samplers: biological perspective, p 269283. In Cox CS,, Wathes CM (eds), Bioaerosols handbook. CRC Press Inc, Boca Raton, FL.
38. Zimmerman J, Reist PC, Turner AG. 1987. Comparison of two biological aerosol sampling methods. Appl Environ Microbiol 53:99104.[PubMed]
39. Utrup LJ, Frey AH. 2004. Fate of bioterrorism-relevant viruses and bacteria, including spores, aerosolized into an indoor air environment. Experiment Biol Med 229:345350.
40. Agranovski IE, Safatov AS, Borodulin AI, Pyankov OV, Petrishchenko VA, Sergeev AN, Agafonov AP, Ignatiev GM, Sergeev AA, Agranovski V. 2004. Inactivation of viruses in bubbling processes utilized for personal bioaerosol monitoring. Appl Environ Microbiol 70:69636967.[PubMed][CrossRef]
41. Franz DR, Jahrling PB, Friedlander AM, McClain DJ, Hoover DL, Bryne WR, Pavlin JA, Christopher GW, Eitzen EM,Jr. 1997. Clinical recognition and management of patients exposed to biological warfare agents. J Am Med Assoc 278:399411.[CrossRef]
42. Verreault D, Moineau S, Duchaine C. 2008. Methods for sampling of airborne viruses. Microbiol Mol Biol Rev 72:413444.[PubMed][CrossRef]
43. Casal J, Planas-Cuchi E, Casal J. 1999. Sheltering as a protective measure against airborne virus spread. J Haz Mat 68:179189.[CrossRef]
44. Clark RP., 1995. Safety cabinets, fume cupboards and other containment systems, p 473504. In Cox CS,, Wathes CM (eds), Bioaerosols handbook. CRC Press, Boca Raton, CL.
45. Clark S, Scarpino P., 1996. Disinfection of microbial aerosols, p 215223. In Hurst CJ (ed), Modeling disease transmission and its prevention by disinfection. Cambridge University Press, Cambridge, UK.
46. Cox CS. 1987. The aerobiological pathway of microorganisms. John Wiley & Sons, Chichester, UK.
47. Cox CS. 1989. Airborne bacteria and viruses. Sci Prog 73:469499.[PubMed]
48. Ijaz MK, Sattar SA, Alkarmi T, Dar FK, Bhatti AR, Elhag KM. 1994. Studies on the survival of aerosolized bovine rotavirus (Uk) and a murine rotavirus. Compr Immunol Microbiol Infect Dis 17:9198.[CrossRef]
49. Mitchell JP., 1995. Aerosol generation for instrument calibration, p 101175. In Cox CS,, Wathes CM (eds), Bioaerosols handbook. CRC Press, Boca Raton, FL.
50. Mitchell JP., 1995. Particle size analyzers: practical procedures and laboratory techniques, p 177246. In Cox CS,, Wathes CM (eds), Bioaerosols handbook. CRC Press, Boca Raton, FL.
51. Spendlove JC. 1957. Production of bacterial aerosols in a rendering plant process. Pub Hlth Rep 72:176180.[CrossRef]
52. Wathes CM, Johnson HE. 1991. Physical protection against airborne pathogens and pollutants by a novel animal isolator in a level 3 containment laboratory. Epidemiol Infect 107:157170.[PubMed][CrossRef]
53. Fleming DO, Richardson JH, Tulis JJ, Vesley D. 2000. Laboratory safety: principles and practices. ASM Press, Washington, DC.
54. Frankova V. 1975. Inhalatory infection of mice with influenza A0/PR8 virus. I. The site of primary virus replication and its spread in the respiratory tract. Acta Virol 19:2934.[PubMed]
55. Knoch M, Wunderlich E, Geldner S. 1994. A nebulizer system for highly reproducible aerosol delivery. J Aerosol Med Dep Clear Eff Lung 7:229237.[CrossRef]
56. Ijaz MK, Karim YG, Sattar SA, Johnson-Lussenburg CM. 1987. Development of methods to study the survival of airborne viruses. J Virol Meth 18:87106.[CrossRef]
57. Ijaz MK, Alharbi S, Uduman S, Cheema Y, Sheek-Hussen MM, Alkhair AR, Shalabi AG, Ijaz MK, Bin-Othman SA, Sattar SA, Liddle LF. 1994. Seasonality and prevalence of rotavirus in Al-Ain, United Arab Emirates. Clin Diagn Virol 2:323329.[PubMed][CrossRef]
58. Goldberg LJ, Watkins HM, Boerke EE, Chatigny MA. 1958. The use of a rotating drum for the study of aerosols over extended periods of time. Am J Hyg 68:8593.[PubMed]
59. Kournikakis B, Simpson M, Netolitzky D. 1988. Photoinactivation of Newcastle disease virus in aerosol and in solution. Defence Research Establishment Suffield, Ralston, AB.
60. May KR, Druett HA. 1968. A microthread technique for studying the viability of microbes in a simulated airborne state. J Gen Microbiol 51:353366.[PubMed][CrossRef]
61. Wallis C, Melnick JL, Rao VC, Sox TE. 1985. Method for detecting viruses in aerosols. Appl Environ Microbiol 50:11811186.[PubMed]
62. May KR. 1966. Multistage liquid impinger. Bacteriol Rev 30:559570.[PubMed]
63. Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA. 2012. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med 367:18141820.[PubMed][CrossRef]
64. Lippmann M. 1961. A compact cascade impactor for field survey sampling. Am Ind Hyg Assoc J 22:348353.[PubMed][CrossRef]
65. Fabian P, McDevitt JJ, Houseman EA, Milton DK. 2009. Airborne influenza virus detection with four aerosol samplers using molecular and infectivity assays: considerations for a new infectious virus aerosol sampler. Indoor Air 19:433441.[PubMed][CrossRef]
66. McKissick GE, Griesemer RA, Farrell RL. 1970. Aerosol transmission of Rauscher murine leukemia virus. J Natl Cancer Inst 45:625636.[PubMed]
67. Hinshaw VS, Schaffer FL, Chatigny MA. 1976. Evaluation of Moloney murine sarcoma and leukemia-virus complex as a model for airborne oncogenic virus biohazards—survival of airborne virus and exposure of mice. J Natl Cancer Inst 57:775778.[PubMed]
68. Davis GW, Grieseme RA, Shadduck JA, Farrell RL. 1971. Effect of relative humidity on dynamic aerosols of adenovirus-12. Appl Microbiol 21:676679.[PubMed]
69. Couch RB, Cate TR, Douglas RG Jr., Gerone PJ, Knight V. 1966. Effect of route of inoculation on experimental respiratory viral disease in volunteers and evidence for airborne transmission. Bacteriol Rev 30:517529.[PubMed]
70. Jericho KWF, Kozub GC. 2004. Experimental infectious respiratory disease in groups of calves: lobar distribution, variance, and sample-size requirements for vaccine evaluation. Can J Vet Res 68:118127.[PubMed]
71. van der Veen J, Poort Y, Birchfield DJ. 1972. Effect of relative humidity on experimental transmission of Sendai virus in mice. 1. Proc Soc Exp Biol Med 140:14371440.[PubMed][CrossRef]
72. Calnek BW, Hitchner SB. 1973. Survival and disinfection of Mareks-disease virus and effectiveness of filters in preventing airborne dissemination. Poult Sci 52:3543.[PubMed][CrossRef]
73. Abdul-Careem MF, Javaheri-Vayeghan A, Shanmuganathan S, Haghighi HR, Read LR, Haq K, Hunter DB, Schat KA, Heidari M, Sharif S. 2009. Establishment of an aerosol-based Marek's disease virus infection model. Avian Dis 53:387391.[PubMed][CrossRef]
74. Kim SJ, Spradbrow PB. 1978. Administration of a vaccine prepared from the Australian V4 strain of Newcastle disease virus by aerosol and drinking water. Aust Vet J 54:486489.[PubMed][CrossRef]
75. Hugh-Jones M, Allan WH, Dark FA, Harper GJ. 1973. The evidence for the airborne spread of Newcastle disease. J Hyg (Lond) 71:325339.[CrossRef]
76. Li X, Chai T, Wang Z, Song C, Cao H, Liu J, Zhang X, Wang W, Yao M, Miao Z. 2009. Occurrence and transmission of Newcastle disease virus aerosol originating from infected chickens under experimental conditions. Vet Microbiol 136:226232.[PubMed][CrossRef]
77. Fairchild GA. 1974. Ozone effect on respiratory deposition of vesicular stomatitis virus aerosols. Am Rev Respir Dis 109:446451.[PubMed]
78. Frankova V, Rychterova V. 1975. Inhalatory infection of mice with influenza A0/PR8 virus. II. Detection of the virus in the blood and extrapulmonary organs. Acta Virol 19:3540.[PubMed]
79. Maigetter RZ, Ehrlich R, Fenters JD, Gardner DE. 1976. Potentiating effects of manganese-dioxide on experimental respiratory infections. Environ Res 11:386391.[PubMed][CrossRef]
80. Owens SL, Osebold JW, Zee YC. 1981. Dynamics of B-lymphocytes in the lungs of mice exposed to aerosolized influenza virus. Infect Immun 33:231238.[PubMed]
81. Johansson BE, Kilbourne ED. 1991. Comparison of intranasal and aerosol infection of mice in assessment of immunity to influenza-virus infection. J Virol Methods 35:109114.[PubMed][CrossRef]
82. Mumford JA, Jessett DM, Rollinson EA, Hannant D, Draper ME. 1994. Duration of protective efficacy of equine influenza immunostimulating complex/tetanus vaccines. Vet Rec 134:158162.[PubMed][CrossRef]
83. Gruber WC, Hinson HP, Holland KL, Thompson JM, Reed GW, Wright PF. 1993. Comparative trial of large-particle aerosol and nose drop administration of live attenuated influenza vaccines. J Infect Dis 168:12821285.[PubMed][CrossRef]
84. Paillot R, Hannant D, Kydd JH, Daly JM. 2006. Vaccination against equine influenza: quid novi? Vaccine 24:40474061.[PubMed][CrossRef]
85. Bowen LE, Rivers K, Trombley JE, Bohannon JK, Li SX, Boydston JA, Eichelberger MC. 2012. Development of a murine nose-only inhalation model of influenza: comparison of disease caused by instilled and inhaled A/PR/8/34. Front Cell Infect Microbiol 2:74.[PubMed][CrossRef]
86. Lednicky JA, Hamilton SB, Tuttle RS, Sosna WA, Daniels DE, Swayne DE. 2010. Ferrets develop fatal influenza after inhaling small particle aerosols of highly pathogenic avian influenza virus A/Vietnam/1203/2004 (H5N1). Virol J 7:231.[PubMed][CrossRef]
87. Tuttle RS, Sosna WA, Daniels DE, Hamilton SB, Lednicky JA. 2010. Design, assembly, and validation of a nose-only inhalation exposure system for studies of aerosolized viable influenza H5N1 virus in ferrets. Virol J 7:135.[PubMed][CrossRef]
88. Frank GH, Marshall RG, Smith PC. 1977. Clinical and immunologic responses of cattle to infectious bovine rhinotracheitis virus after infection by viral aerosol or intramuscular inoculation. Am J Vet Res 38:14971502.[PubMed]
89. Belknap EB, Collins JK, Ayers VK, Schultheiss PC. 1994. Experimental-infection of neonatal calves with neurovirulent bovine herpesvirus type-1.3. Vet Path 31:358365.[CrossRef]
90. Mars MH, Bruschke CJ, van Oirschot TJ. 1999. Airborne transmission of BHV1, BRSV, and BVDV among cattle is possible under experimental conditions. Vet Microbiol 66:197207.[PubMed][CrossRef]
91. Elazhary MA, Galina M, Roy RS, Fontaine M, Lamothe P. 1980. Experimental infection of calves with bovine respiratory syncytial virus (Quebec strain). Can J Comp Med 44:390395.[PubMed]
92. Sacco RE, Nonnecke BJ, Palmer MV, Waters WR, Lippolis JD, Reinhardt TA. 2012. Differential expression of cytokines in response to respiratory syncytial virus infection of calves with high or low circulating 25-hydroxyvitamin D3. PLoS One 7:e33074. doi:10.1371/journal.pone.0033074.[PubMed][CrossRef] http://dx.doi.org/10.1371/journal.pone.0033074
93. Wardley RC, Povey RC. 1977. Aerosol transmission of feline calciciviruses. An assessment of its epidemiological importance. Brit Vet J 133:504508.
94. Omerod E, McClandlish IA, Jarrett O. 1979. Disease produced by feline caliciviruses. Vet Rec 104:6569.[CrossRef]
95. Wilkinson PJ, Donaldson AI. 1977. Transmission studies with African swine fever virus. The early distribution of virus in pigs infected by airborne virus. J Comp Pathol 87:497501.[PubMed][CrossRef]
96. Wilkinson PJ, Donaldson AI, Greig A, Bruce W. 1977. Transmission studies with African swine fever virus. Infections of pigs by airborne virus. J Comp Pathol 87:487495.[PubMed][CrossRef]
97. Hyslop NS. 1979. Observations on the survival and infectivity of airborne Rinderpest virus. Int J Biometeorol 23:17.[PubMed][CrossRef]
98. Larson EW, Dominik JW, Slone TW. 1980. Aerosol stability and respiratory infectivity of Japanese B-encephalitis virus. Infect Immun 30:397401.[PubMed]
99. Merekalova ZI, Orekhova NM, Zharona EI. 1981. Possible ways of excreting murine leukemia virus into the environment and the so-called input gate for infection. Exper Oncol 3:5962.
100. Arzt J, Pacheco JM, Rodriguez LL. 2010. The early pathogenesis of foot-and-mouth disease in cattle after aerosol inoculation. Identification of the nasopharynx as the primary site of infection. Vet Pathol 47:10481063.[PubMed][CrossRef]
101. McVicar JW, Eisner RJ. 1983. Aerosol exposure of cattle to foot-and-mouth disease virus. J Hyg (Lond) 91:319328.[CrossRef]
102. Brown CC, Meye RF, Olander HJ, House C, Mebus CA. 1992. A pathogenesis study of foot-and-mouth-disease in cattle, using in situ hybridization. Can J Vet Res 56:189193.[PubMed]
103. Donaldson AI, Wardley RC, Martin S, Ferris NP. 1983. Experimental Aujeszky's disease in pigs: excretion, survival and transmission of the virus. Vet Rec 113:490494.[PubMed][CrossRef]
104. Gillespie RR, Hill MA, Kanitz CL, Knox KE, Clark LK, Robinson JP. 2000. Infection of pigs by Aujeszky's disease virus via the breath of intranasally inoculated pigs. Res Vet Sci 68:217222.[PubMed][CrossRef]
105. Gillespie RR, Hill MA, Kanitz CL. 1996. Infection of pigs by aerosols of Aujeszky's disease virus and their shedding of the virus. Res Vet Sci 60:228233.[PubMed][CrossRef]
106. Ratanasethakul C, Cumming RB. 1983. The effect of route of infection and strain of virus on the pathology of Australian infectious bronchitis. Aust Vet J 60:209213.[PubMed][CrossRef]
107. Stephenson EH, Larson EW, Dominik JW. 1984. Effect of environmental factors on aerosol-induced Lassa virus infection. J Med Virol 14:295303.[PubMed][CrossRef]
108. Prince DS, Astry C, Vonderfecht S, Jakab G, Shen FM, Yolken RH. 1986. Aerosol transmission of experimental rotavirus infection. Pediatr Infect Dis 5:218222.[PubMed][CrossRef]
109. Anderson GW, Lee JO, Anderson AO, Powell N, Mangiafico JA, Meadors G. 1991. Efficacy of a Rift-Valley fever virus-vaccine against an aerosol infection in rats. Vaccine 9:710714.[PubMed][CrossRef]
110. Morrill JC, Peters CJ. 2011. Protection of MP-12-vaccinated rhesus macaques against parenteral and aerosol challenge with virulent rift valley fever virus. J Infect Dis 204:229236.[PubMed][CrossRef]
111. Bhardwaj N, Pierce BR, Ross TM. 2012. Immunization with DNA vaccine expressing Gn coupled to C3d prevents clinical symptoms of infection and protects mice against an aerosol Rift Valley fever virus infection. J Bioterr Biodefense 2:S3:006.[CrossRef]
112. Nuzum EO, Rossi CA, Stephenson EH, Leduc JW. 1988. Aerosol transmission of Hantaan and related viruses to laboratory rats. Am J Trop Med Hyg 38:636640.[PubMed]
113. McElroy AK, Smith JM, Hooper JW, Schmaljohn CS. 2004. Andes virus M genome segment is not sufficient to confer the virulence associated with Andes virus in Syrian hamsters. Virol 326:130139.[CrossRef]
114. Deuter A, Southee DJ, Mockett APA. 1991. Fowlpox virus—pathogenicity and vaccination of day-old chickens via the aerosol route. Res Vet Sci 50:362364.[PubMed][CrossRef]
115. Pokhodiaev VA, Gonchar NI, Pshenichnov VA. 1991. An experimental study of the contact transmission of the Marburg virus. Vopr Virusol 36:506508.[PubMed]
116. Geisbert TW, Daddario-Dicaprio KM, Geisbert JB, Reed DS, Feldmann F, Grolla A, Stroher U, Fritz EA, Hensley LE, Jones SM, Feldmann H. 2008. Vesicular stomatitis virus-based vaccines protect nonhuman primates against aerosol challenge with Ebola and Marburg viruses. Vaccine 26:68946900.[PubMed][CrossRef]
117. Alves DA, Glynn AR, Steele KE, Lackemeyer MG, Garza NL, Buck JG, Mech C, Reed DS. 2010. Aerosol exposure to the Angola strain of Marburg virus causes lethal viral hemorrhagic fever in cynomolgus macaques. Vet Pathol 47:831851.[PubMed][CrossRef]
118. Goodman LB, Wagner B, Flaminio MJ, Sussman KH, Metzger SM, Holland R, Osterrieder N. 2006. Comparison of the efficacy of inactivated combination and modified-live virus vaccines against challenge infection with neuropathogenic equine herpesvirus type 1 (EHV-1). Vaccine 24:36363645.[PubMed][CrossRef]
119. Kenyon RH, Mckee KT, Zack PM, Rippy MK, Vogel AP, York C, Meegan J, Crabbs C, Peters CJ. 1992. Aerosol infection of rhesus macaques with Junin virus. Intervirol 33:2331.
120. Smith KC, Whitwell KE, Binns MM, Dolby CA, Hannant D, Mumford JA. 1992. Abortion of virologically negative foetuses following experimental challenge of pregnant pony mares with equid herpesvirus 1. Equine Vet J 24:256259.[PubMed][CrossRef]
121. Brim TA, Vancott JL, Lunney JK, Saif LJ. 1994. Lymphocyte-proliferation responses of pigs inoculated with transmissible gastroenteritis virus or porcine respiratory coronavirus. Am J Vet Res 55:494501.[PubMed]
122. Pratt WD, Gibbs P, Pitt ML, Schmaljohn AL. 1998. Use of telemetry to assess vaccine-induced protection against parenteral and aerosol infections of Venezuelan equine encephalitis virus in non-human primates. Vaccine 16:10561064.[PubMed][CrossRef]
123. Phillpotts RJ, O'brien L, Appleton RE, Carr S, Bennett A. 2005. Intranasal immunisation with defective adenovirus serotype 5 expressing the Venezuelan equine encephalitis virus E2 glycoprotein protects against airborne challenge with virulent virus. Vaccine 23:16151623.[PubMed][CrossRef]
124. Taus NS, Traul DL, Oaks JL, Crawford TB, Lewis GS, Li H. 2005. Experimental infection of sheep with ovine herpesvirus 2 via aerosolization of nasal secretions. J Gen Virol 86:575579.[PubMed][CrossRef]
125. Li H, O'Toole D, Ki O, Oaks JL, Crawford TB. 2005. Malignant catarrhal fever-like disease in sheep after intranasal inoculation with ovine herpesvirus-2. J Vet Diagn Invest 17:171175.[PubMed][CrossRef]
126. Taus NS, Oaks JL, Gailbreath K, Traul DL, O'Toole D, Li H. 2006. Experimental aerosol infection of cattle (Bos taurus) with ovine herpesvirus 2 using nasal secretions from infected sheep. Vet Microbiol 116:2936.[PubMed][CrossRef]
127. Gailbreath KL, Taus NS, Cunha CW, Knowles DP, Li H. 2008. Experimental infection of rabbits with ovine herpesvirus 2 from sheep nasal secretions. Vet Microbiol 132:6573.[PubMed][CrossRef]
128. Li H, Cunha CW, Davies CJ, Gailbreath KL, Knowles DP, Oaks JL, Taus NS. 2008. Ovine herpesvirus 2 replicates initially in the lung of experimentally infected sheep. J Gen Virol 89:16991708.[PubMed][CrossRef]
129. Li H, Brooking A, Cunha CW, Highland MA, O'Toole D, Knowles DP, Taus NS. 2012. Experimental induction of malignant catarrhal fever in pigs with ovine herpesvirus 2 by intranasal nebulization. Vet Microbiol 159:485489.[PubMed][CrossRef]
130. Jahrling PB, Hensley LE, Martinez MJ, Leduc JW, Rubins KH, Relman DA, Huggins JW. 2004. Exploring the potential of variola virus infection of cynomolgus macaques as a model for human smallpox. Proc Nat Acad Sci 101:1519615200.[PubMed][CrossRef]
131. Nalca A, Nichols DK. 2011. Rabbitpox: a model of airborne transmission of smallpox. J Gen Virol 92:3135.[PubMed][CrossRef]
132. Dee SA, Deen J, Jacobson L, Rossow KD, Mahlum C, Pijoan C. 2005. Laboratory model to evaluate the role of aerosols in the transport of porcine reproductive and respiratory syndrome virus. Vet Rec 156:501504.[PubMed][CrossRef]
133. Cho JG, Deen J, Dee SA. 2007. Influence of isolate pathogenicity on the aerosol transmission of porcine reproductive and respiratory syndrome virus. Can J Vet Res 71:2327.[PubMed]
134. Henderson DW. 1952. An apparatus for the study of airborne infection. J Hyg (Lond) 50:5368.[CrossRef]
135. Osborne AD, Saunders JR, Sebunya TK, Willson P, Green GH. 1985. A simple aerosol chamber for experimental reproduction of respiratory disease in pigs and other species. Can J Comp Med 49:434435.[PubMed]
136. Chung IP, Dunnrankin D, Phalen RF, Oldham MJ. 1992. Low-cost wind-tunnel for aerosol inhalation studies. Am Industl Hyg Assoc J 53:232236.[CrossRef]
137. Cole EC, Cook CE. 1998. Characterization of infectious aerosols in health care facilities: an aid to effective engineering controls and preventive strategies. Am J Infect Contrl 26:453464.[CrossRef]
138. Pike RM. 1979. Laboratory-associated infections: incidence, fatalities, causes, and prevention. Annu Rev Microbiol 33:4166.[PubMed][CrossRef]
139. Biosafety in Microbiological and Biomedical Laboratories 2009. 5th ed. U. S. Government Printing Office, Washington, DC. http://www.cdc.gov/biosafety/publications/bmbl5/.
140. Benbough JE. 1971. Some factors affecting the survival of airborne viruses. J Gen Virol 10:209220.[PubMed][CrossRef]
141. Yang W, Marr CL. 2012. Mechanisms by which ambient humidity may affect viruses in aerosols. Appl Environ Microbiol 78:67816788.[PubMed][CrossRef]
142. Sawchuk WS, Weber PJ, Lowy DR, Dzubow LM. 1989. Infectious papillomavirus in the vapor of warts treated with carbon dioxide laser or electrocoagulation: detection and protection. J Am Acad Dermatol 21:4149.[PubMed][CrossRef]
143. Hepburn NC, Brooks TJG. 1991. An outbreak of chickenpox in a military field hospital—the implications for biological warfare. J Roy Soc Med 84:721722.[PubMed]
144. Suzuki K, Yoshikawa T, Ihira M, Ohashi M, Suga S, Asano Y. 2003. Spread of varicella-zoster virus DNA to the environment from varicella patients who were treated with oral acyclovir. Pediatr Int 45:458460.[PubMed][CrossRef]
145. Caul EO. 1994. Small round-structured airuses—airborne transmission and hospital control. Lancet 343:12401242.[PubMed][CrossRef]
146. Gellert GA, Waterman SH, Ewert D, Oshiro L, Giles MP, Monroe SS, Gorelkin L, Glass RI. 1990. An outbreak of acute gastroenteritis caused by a small round structured virus in a geriatric convalescent facility. Infect Contrl Hosp Epidemiol 11:459464.[CrossRef]
147. Chadwick PR, Walker M, Rees AE. 1994. Airborne transmission of a small round-structured virus. Lancet 343:171.[PubMed][CrossRef]
148. Saif LJ, Theil KW. 1990. Viral diarrheas of man and animals. CRC Press, Boca Raton, FL.
149. Ijaz MK, Sattar SA, Johnson-Llussenburg CM, Springthorpe VS. 1985. Comparison of the airborne survival of calf rotavirus and poliovirus type-1 (Sabin) aerosolized as a mixture. Appl Environ Microbiol 49:289293.[PubMed]
150. Patel MM, Pitzer VE, Alonso WJ, Vera D, Lopman B, Tate J, Viboud C, Parashar UD. 2013. Global seasonality of rotavirus disease. Pediatr Infect Dis J 32:e134–e147. doi:10.1097/INF.0b013e31827d3b68.[PubMed][CrossRef] http://dx.doi.org/10.1097/INF.0b013e31827d3b68
151. Dick EC, Jennings LC, Mink KA, Wartgow CD, Inhorn SL. 1987. Aerosol transmission of rhinovirus colds. J Infect Dis 156:442448.[PubMed][CrossRef]
152. Gwaltney JM., 1997. Rhinoviruses, p 815838. In Evans AS,, Kaslow RA (eds), Viral infections of humans: epidemiology and control, 4th ed. Plenum Medical, New York.
153. Karim YG, Ijaz MK, Sattar SA, Johnson-Lussenburg CM. 1985. Effect of relative humidity on the airborne survival of rhinovirus-14. Can J Microbiol 31:10581061.[PubMed][CrossRef]
154. Calero L, Brusis T. 2003. Laryngeal papillomatosis—first recognition in Germany as an occupational disease in an operating room nurse. Laryngo-Rhino-Otolo 82:790793.[CrossRef]
155. Hallmo P, Naess O. 1991. Laryngeal papillomatosis with human papillomavirus DNA contracted by a laser surgeon. Eur Arch Otorhinolaryngol 248:425427.[PubMed][CrossRef]
156. Manson LT, Damrose EJ. 2013. Does exposure to laser plume place the surgeon at high risk for acquiring clinical human papillomavirus infection? Laryngoscope 123:13191320.[PubMed][CrossRef]
157. Kashima HK, Kessis T, Mounts P, Shah K. 1991. Polymerase chain-reaction identification of human papillomavirus DNA in CO2-laser plume from recurrent respiratory papillomatosis. Otolaryngol Head Neck Surg 104:191195.[PubMed]
158. Wisniewski PM, Warhol MJ, Rando RF, Sedlacek TV, Kemp JE, Fisher JC. 1990. Studies on the transmission of viral disease via the CO2-laser plume and ejecta. J Reprod Med 35:11171123.[PubMed]
159. Bergbrant IM, Samuelsson L, Olofsson S, Jonassen F, Ricksten A. 1994. Polymerase chain-reaction for monitoring human papillomavirus contamination of medical personnel during treatment of genital warts with CO2-laser and electrocoagulation. Acta Dermato-Venereolog 74:393395.
160. Barrett WL, Garber SM. 2003. Surgical smoke—a review of the literature—is this just a lot of hot air? Surg Endosc Other Intervent Tech 17:979987.[CrossRef]
161. Johnson GK, Robinson WS. 1991. Human immunodeficiency virus-1 (HIV-1) in the vapors of surgical power instruments. J Med Virol 33:4750.[PubMed][CrossRef]
162. Jewett DL, Heinsohn P, Bennett C, Rosen A, Neuilly C. 1992. Blood-containing aerosols generated by surgical techniques—a possible infectious hazard. Am Indust Hyg Assoc J 53:228231.[CrossRef]
163. Baggish MS, Poiesz BJ, Joret D, Williamson P, Refai A. 1991. Presence of human-immunodeficiency-virus DNA in laser smoke. Lasers Surg Med 11:197203.[PubMed][CrossRef]
164. Leffel EK, Reed DS. 2004. Marburg and Ebola viruses as aerosol threats. Biosec Bioterr Biodef Strat Pract Sci 2:186191.[CrossRef]
165. Dalgard DW, Hardy RJ, Pearson SL, Pucak GJ, Quander RV, Zack PM, Peters CJ, Jahrling PB. 1992. Combined simian hemorrhagic-fever and Ebola virus-infection in cynomolgus monkeys. Lab Animal Sci 42:152157.
166. Leduc JW. 1989. Epidemiology of hemorrhagic fever viruses. Rev Infect Dis 11:S730S735.[PubMed][CrossRef]
167. Alexeyev OA, Baranov BA. 1993. Puumala virus infection without signs of renal involvement. Scand J Infect Dis 25:525527.[PubMed][CrossRef]
168. Lee HW, Johnson KM. 1982. Laboratory-acquired infections with Hantaan virus, the etiologic agent of Korean hemorrhagic fever. J Infect Dis 146:645651.[PubMed][CrossRef]
169. Niklasson BS. 1992. Haemorrhagic fever with renal syndrome, virological and epidemiological aspects. Pediatr Nephrol 6:201204.[PubMed][CrossRef]
170. Peters CJ, Khan AS. 2002. Hantavirus pulmonary syndrome: the new American hemorrhagic fever. Clin Infect Dis 34:12241231.[PubMed][CrossRef]
171. Wong TW, Chan YC, Yap EH, Joo YG, Lee HW, Lee PW, Yanagihara R, Gibbs CJ Jr., Gajdusek DC. 1988. Serological evidence of hantavirus infection in laboratory rats and personnel. Int J Epidemiol 17:887890.[PubMed][CrossRef]
172. Keeler N, Lingappa L. 2004. Severe acute respiratory syndrome: public health response and clinical practice update for an emerging disease. Curr Opin Pediatr 16:6169.[PubMed][CrossRef]
173. Ng SK. 2003. Possible role of an animal vector in the SARS outbreak at Amoy Gardens. Lancet 362:570572.[PubMed][CrossRef]
174. Somogyi R, Vesely AE, Azami T, Preiss D, Fisher J, Correia J, Fowler RA. 2004. Dispersal of respiratory droplets with open vs closed oxygen delivery masks: implications for the transmission of severe acute respiratory syndrome. Chest 125:11551157.[PubMed][CrossRef]
175. Ijaz MK, Brunner AH, Sattar SA, Nair RC, Johnson-Lussenburg CM. 1985. Survival characteristics of airborne human coronavirus-229E. J Gen Virol 66:27432748.[PubMed][CrossRef]
176. Saw TA, Lim W, Shortridge K, Tam J, Liu KK, Mak KH, Tsang T, Ho YY, Lee FY, Kwong H. 1998. Isolation of avian influenza A (H5N1) viruses from humans—Hong Kong, May–December 1997. J Am Med Assoc 279:263264.[CrossRef]
177. Imperiale MJ, Hanna MGIII 2012. Biosafety considerations of mammalian-transmissible H5N1 influenza. MBio 3:e0004312. doi:10.1128/mBio.00043-12.[PubMed][CrossRef] http://dx.doi.org/10.1128/mBio.00043-12
178. Moutou F, Durand B. 1994. Modelling the spread of foot-and-mouth disease virus. Vet Res 25:279285.[PubMed]
179. Kandeil A, El-Shesheny R, Kayali G, Moatasim Y, Bagato O, Darwish M, Gaffar A, Younes A, Farag T, Kutkat MA, Ali MA. 2013. Characterization of the recent outbreak of foot-and-mouth disease virus serotype SAT2 in Egypt. Arch Virol 158:619627.[PubMed][CrossRef]
180. Park JH, Lee KN, Ko YJ, Kim SM, Lee HS, Park JY, Yeh JY, Kim MJ, Lee YH, Sohn HJ, Cho IS, Kim B. 2013. Diagnosis and control measures of the 2010 outbreak of foot-and-mouth disease A type in the Republic of Korea. Transbound Emerg Dis 60:188192.[PubMed][CrossRef]
181. Gibson CF, Donaldson AI. 1986. Exposure of sheep to natural aerosols of foot-and-mouth disease virus. Res Vet Sci 41:4549.[PubMed]
182. Hopkins SR, Drury LN. 1971. Efficacy of air filters in preventing transmission of Newcastle Disease. Avian Dis 15:596603.[PubMed][CrossRef]
183. Kournikakis B, Netolitzky D, Fildes J. 1987. Effects of temperature and relative humidity on the survival of Newcastle Disease Virus aerosols in the rotating drum (U). (1261). Defence Research Establishment Suffield, Ralston, AB.
184. Burge HA., 1995. Airborne contagious disease, p 2547. In Burge HA (ed), Bioaerosols. CRC Press, Boca Raton, FL.
185. Mitchell BW, King DJ. 1994. Effect of negative air ionization on airborne transmission of Newcastle disease virus. Avian Dis 38:725732.[PubMed][CrossRef]
186. Schoenbaum MA, Zimmerman JJ, Beran GW, Murphy DP. 1990. Survival of pseudorabies virus in aerosol. Am J Vet Res 51:331333.[PubMed]
187. Cramer SD, Campbell GA, Njaa BL, Morgan SE, Smith SK, McLin WR, Brodersen BW, Wise AG, Scherba G, ILangohr IM, Maes RK. 2011. Pseudorabies virus infection in Oklahoma hunting dogs. J Vet Diagn Invest 23:915923.[PubMed][CrossRef]
188. Winkler WG. 1968. Airborne rabies virus isolation. Wildl Dis 4:3740.[PubMed][CrossRef]
189. Winkler WG, Fashinell TR, Leffingwell L, Howard P, Conomy P. 1973. Airborne rabies transmission in a laboratory worker. J Am Med Assoc 226:12191221.[CrossRef]
190. Sattar SA. 2004. Microbicides and the environmental control of nosocomial viral infections. J Hosp Infect 56(Suppl 2):S64S69.[PubMed][CrossRef]
191. Sattar SA. 2007. Hierarchy of susceptibility of viruses to environmental surface disinfectants: a predictor of activity against new and emerging viral pathogens. J AOAC Int 90:16551658.[PubMed]
192. Griffiths WD, Bennett A, Speight S, Parks S. 2005. Determining the performance of a commercial air purification system for reducing airborne contamination using model micro-organisms: a new test methodology. J Hosp Infect 61:242247.[PubMed][CrossRef]
193. Cutler TD, Wang C, Hoff SJ, Zimmerman JJ. 2012. Effect of temperature and relative humidity on ultraviolet (UV 254) inactivation of airborne porcine respiratory and reproductive syndrome virus. Vet Microbiol 159:4752.[PubMed][CrossRef]
194. McDevitt JJ, Rudnick SN, Radonovich LJ. 2012. Aerosol susceptibility of influenza virus to UV-C light. Appl Environ Microbiol 78:16661669.[PubMed][CrossRef]
195. McDevitt JJ, Milton DK, Rudnick SN, First MW. 2008. Inactivation of poxviruses by upper-room UVC light in a simulated hospital room environment. PLoS One 3:e3186. doi:10.1371/journal.pone.0003186.[PubMed][CrossRef] http://dx.doi.org/10.1371/journal.pone.0003186
196. McDevitt JJ, Lai KM, Rudnick SN, Houseman EA, First MW, Milton DK. 2007. Characterization of UVC light sensitivity of vaccinia virus. Appl Environ Microbiol 73:57605766.[PubMed][CrossRef]