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Chapter 12 : Enteroviruses and Parechoviruses
Category: Clinical Microbiology
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Human enteroviruses (EVs) and parechoviruses (HPeV) belong to the family Picornaviridae ( 1 ). The human enteroviruses are classified into four species based on molecular and biologic characteristics: human enterovirus A (HEV A), HEV B, HEV C, and HEV D, with the traditional names retained for individual serotypes ( Table 1 ). Genetic characterization of two echovirus serotypes, 22 and 23, has resulted in their reclassification into a separate new genus, Parechovirus, and they are termed HPeV 1 and 2, respectively. Subsequent studies have demonstrated that there are now 16 distinct HPeV types, of which HPeV 1–6 are known to cause infections in humans.