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Virulence Mechanisms of Bacterial Pathogens, Fifth Edition

Editors: Indira T. Kudva1, Nancy A. Cornick2, Paul J. Plummer3, Qijing Zhang4, Tracy L. Nicholson5, John P. Bannantine6, Bryan H. Bellaire7
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Affiliations: 1: National Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Ames, IA 50010; 2: Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011; 3: Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011; 4: Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011; 5: National Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Ames, IA 50010; 6: National Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Ames, IA 50010; 7: Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011
Content Type: Monograph
Publication Year: 2016
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Despite the use of antibiotics, bacterial diseases continue to be a critical issue in public health, and bacterial pathogenesis remains a tantalizing problem for research microbiologists. This new edition of Virulence Mechanisms of Bacterial Pathogens broadly covers the knowledge base surrounding this topic and presents recently unraveled bacterial virulence strategies and cutting-edge therapies.

A team of editors, led by USDA scientist Indira Kudva, compiled perspectives from experts to explain the wide variety of mechanisms through which bacterial pathogens cause disease: the host interface, host cell enslavement, and bacterial communication, secretion, defenses, and persistence. A collection of reviews on targeted therapies rounds out the seven sections of this unique book. The new edition provides insights into some of the most recent advances in the area of bacterial pathogenesis, including:

  • how metabolism shapes the host-pathogen interface
  • interactions across species and genera
  • secretion systems mechanisms
  • evasion, survival, and persistence mechanisms
  • new therapies targeting various adaptive and virulence mechanisms of bacterial pathogens

Written to promote discussion, extrapolation, exploration, and multidimensional thinking, serves as a textbook for graduate courses on bacterial pathogenesis and a resource for specialists in bacterial pathogenicity, including molecular biologists, physician scientists, infectious disease clinicians, dental scientists, veterinarians, industry researchers, and technicians.

“This new edition of Virulence Mechanisms of Bacterial Pathogens is edited by renowned experts in the field and encompasses state-of-the-art review articles and critical overviews. From bacterial-host interactions and communication to bacterial secretion systems, persistence, and novel targeted therapies, this is a ‘MUST READ’ for anyone studying bacterial infectious agents.”

Carolyn Hovde Bohach, PhD, University Distinguished Professor, University of Idaho School of Food Science; Director, NIH Idaho INBRE Program; President, National Association of IDeA Principal Investigators (NAIPI)

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