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Chapter 29 : Recent Advances and Understanding of Using Probiotic-Based Interventions to Restore Homeostasis of the Microbiome for the Prevention/Therapy of Bacterial Diseases

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Recent Advances and Understanding of Using Probiotic-Based Interventions to Restore Homeostasis of the Microbiome for the Prevention/Therapy of Bacterial Diseases, Page 1 of 2

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Abstract:

The mammalian gastrointestinal (GI) tract is comprised of several hundred species of microorganisms including bacteria, archaea, fungi, bacteriophages, eukaryotic viruses, and protozoa. This complex and eclectic ecosystem is collectively known as the gut microbiota. Bacteria are by far the most abundant constituent of the microbiota; studies using DNA shotgun sequencing analysis have estimated that bacteria make up approximately 98% of all metagenomic sequences in fecal samples of various mammals ( ). The GI microbiota is acquired rapidly after birth and undergoes substantial compositional changes (from a more aerobic to a predominantly anaerobic flora) in the first 1 to 2 years of life before reaching a stable and symbiotic relationship with the host ( ). It then remains dynamic but relatively stable throughout adulthood unless perturbed.

Citation: Suchodolski J, Jergens A. 2016. Recent Advances and Understanding of Using Probiotic-Based Interventions to Restore Homeostasis of the Microbiome for the Prevention/Therapy of Bacterial Diseases, p 823-841. In Kudva I, Cornick N, Plummer P, Zhang Q, Nicholson T, Bannantine J, Bellaire B (ed),

Virulence Mechanisms of Bacterial Pathogens, Fifth Edition

. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.VMBF-0025-2015
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Figure 1

Potential mechanisms for probiotic activity.

Citation: Suchodolski J, Jergens A. 2016. Recent Advances and Understanding of Using Probiotic-Based Interventions to Restore Homeostasis of the Microbiome for the Prevention/Therapy of Bacterial Diseases, p 823-841. In Kudva I, Cornick N, Plummer P, Zhang Q, Nicholson T, Bannantine J, Bellaire B (ed),

Virulence Mechanisms of Bacterial Pathogens, Fifth Edition

. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.VMBF-0025-2015
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Image of Figure 2
Figure 2

Three-color FISH identifies mucosal bacteria adherent to the colonic mucosa in a dog receiving probiotic VSL #3 as therapy for IBD. spp. appear orange (Erec482-Cy3 probe) against green (Eub338-FITC probe) and blue (DAPI stain) backgrounds.

Citation: Suchodolski J, Jergens A. 2016. Recent Advances and Understanding of Using Probiotic-Based Interventions to Restore Homeostasis of the Microbiome for the Prevention/Therapy of Bacterial Diseases, p 823-841. In Kudva I, Cornick N, Plummer P, Zhang Q, Nicholson T, Bannantine J, Bellaire B (ed),

Virulence Mechanisms of Bacterial Pathogens, Fifth Edition

. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.VMBF-0025-2015
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References

/content/book/10.1128/9781555819286.chap29
1. Swanson KS,, Dowd SE,, Suchodolski JS,, Middelbos IS,, Vester BM,, Barry KA,, Nelson KE,, Torralba M,, Henrissat B,, Coutinho PM,, Cann IK,, White BA,, Fahey GC Jr . 2011. Phylogenetic and gene-centric metagenomics of the canine intestinal microbiome reveals similarities with humans and mice. ISME J 5 : 639649.[PubMed] [CrossRef]
2. Barry KA,, Middelbos IS,, Vester Boler BM,, Dowd SE,, Suchodolski JS,, Henrissat B,, Coutinho PM,, White BA,, Fahey GC Jr,, Swanson KS . 2012. Effects of dietary fiber on the feline gastrointestinal metagenome. J Proteome Res 11 : 59245933.[PubMed] [CrossRef]
3. Yatsunenko T,, Rey FE,, Manary MJ,, Trehan I,, Dominguez-Bello MG,, Contreras M,, Magris M,, Hidalgo G,, Baldassano RN,, Anokhin AP,, Heath AC,, Warner B,, Reeder J,, Kuczynski J,, Caporaso JG,, Lozupone CA,, Lauber C,, Clemente JC,, Knights D,, Knight R,, Gordon JI . 2012. Human gut microbiome viewed across age and geography. Nature 486 : 222227.[PubMed] [CrossRef]
4. Lederberg JM . 2001. ’Ome sweet ’omics: a genealogical treasury of words. Scientist 15 : 810.
5. Suchodolski JS . 2011. Companion animals symposium: microbes and gastrointestinal health of dogs and cats. J Anim Sci 89 : 15201530.[PubMed] [CrossRef]
6. Human Microbiome Project C . 2012. Structure, function and diversity of the healthy human microbiome. Nature 486 : 207214.[PubMed] [CrossRef]
7. Dunn WB,, Ellis DI . 2005. Metabolomics: current analytical platforms and methodologies. Trends Anal Chem 24 : 285294.[CrossRef]
8. Minamoto Y,, Otoni CC,, Steelman SM,, Buyukleblebici O,, Steiner JM,, Jergens AE,, Suchodolski JS . 2015. Alteration of the fecal microbiota and serum metabolite profiles in dogs with idiopathic inflammatory bowel disease. Gut Microbes 6 : 3347.[PubMed] [CrossRef]
9. Wishart D, . 2007. Metabolomics in humans and other mammals, p 253288. In Villas-Boas SG,, Roessner U,, Hansen AEH,, Smedsgaard J,, Nielsen J (ed), Metabolome Analysis: An Introduction, vol 1. John Wiley & Sons, Hoboken, NJ. [CrossRef]
10. Langille MG,, Zaneveld J,, Caporaso JG,, McDonald D,, Knights D,, Reyes JA,, Clemente JC,, Burkepile DE,, Vega Thurber RL,, Knight R,, Beiko RG,, Huttenhower C . 2013. Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences. Nat Biotechnol 31 : 814821.[PubMed] [CrossRef]
11. Arumugam M,, Raes J,, Pelletier E,, Le Paslier D,, Yamada T,, Mende DR,, Fernandes GR,, Tap J,, Bruls T,, Batto JM,, Bertalan M,, Borruel N,, Casellas F,, Fernandez L,, Gautier L,, Hansen T,, Hattori M,, Hayashi T,, Kleerebezem M,, Kurokawa K,, Leclerc M,, Levenez F,, Manichanh C,, Nielsen HB,, Nielsen T,, Pons N,, Poulain J,, Qin J,, Sicheritz-Ponten T,, Tims S,, Torrents D,, Ugarte E,, Zoetendal EG,, Wang J,, Guarner F,, Pedersen O,, de Vos WM,, Brunak S,, Dore J,, Antolin M,, Artiguenave F,, Blottiere HM,, Almeida M,, Brechot C,, Cara C,, Chervaux C,, Cultrone A,, Delorme C,, Denariaz G,, Dervyn R,, Foerstner KU,, Friss C,, van de Guchte M,, Guedon E,, Haimet F,, Huber W,, van Hylckama-Vlieg J,, Jamet A,, Juste C,, Kaci G,, Knol J,, Lakhdari O,, Layec S,, Le Roux K,, Maguin E,, Mérieux A,, Melo Minardi R,, M’rini C,, Muller J,, Oozeer R,, Parkhill J,, Renault P,, Rescigno M,, Sanchez N,, Sunagawa S,, Torrejon A,, Turner K,, Vandemeulebrouck G,, Varela E,, Winogradsky Y,, Zeller G,, Weissenbach J,, Ehrlich SD,, Bork P . 2011. Enterotypes of the human gut microbiome. Nature 473 : 174180.[PubMed] [CrossRef]
12. Jeffery IB,, Claesson MJ,, O’Toole PW,, Shanahan F . 2012. Categorization of the gut microbiota: enterotypes or gradients? Nat Rev Microbiol 10 : 591592.[PubMed] [CrossRef]
13. Aagaard K,, Petrosino J,, Keitel W,, Watson M,, Katancik J,, Garcia N,, Patel S,, Cutting M,, Madden T,, Hamilton H,, Harris E,, Gevers D,, Simone G,, McInnes P,, Versalovic J . 2013. The Human Microbiome Project strategy for comprehensive sampling of the human microbiome and why it matters. FASEB J 27 : 10121022.[PubMed] [CrossRef]
14. Suchodolski JS,, Markel ME,, Garcia-Mazcorro JF,, Unterer S,, Heilmann RM,, Dowd SE,, Kachroo P,, Ivanov I,, Minamoto Y,, Dillman EM,, Steiner JM,, Cook AK,, Toresson L . 2012. The fecal microbiome in dogs with acute diarrhea and idiopathic inflammatory bowel disease. Plos One 7 : e51907. doi:10.1371/journal.pone.0051907. [CrossRef]
15. Duboc H,, Rajca S,, Rainteau D,, Benarous D,, Maubert MA,, Quervain E,, Thomas G,, Barbu V,, Humbert L,, Despras G,, Bridonneau C,, Dumetz F,, Grill JP,, Masliah J,, Beaugerie L,, Cosnes J,, Chazouilleres O,, Poupon R,, Wolf C,, Mallet JM,, Langella P,, Trugnan G,, Sokol H,, Seksik P . 2013. Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases. Gut 62 : 531539.[PubMed] [CrossRef]
16. Frank DN,, Amand ALS,, Feldman RA,, Boedeker EC,, Harpaz N,, Pace NR . 2007. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci USA 104 : 1378013785.[PubMed] [CrossRef]
17. Sokol H,, Pigneur B,, Watterlot L,, Lakhdari O,, Bermudez-Humaran LG,, Gratadoux JJ,, Blugeon S,, Bridonneau C,, Furet JP,, Corthier G,, Grangette C,, Vasquez N,, Pochart P,, Trugnan G,, Thomas G,, Blottiere HM,, Dore J,, Marteau P,, Seksik P,, Langella P . 2008. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci USA 105 : 1673116736.[PubMed] [CrossRef]
18. Honneffer JB,, Minamoto Y,, Suchodolski JS . 2014. Microbiota alterations in acute and chronic gastrointestinal inflammation of cats and dogs. World J Gastroenterol 20 : 1648916497.[PubMed] [CrossRef]
19. Packey CD,, Sartor RB . 2009. Commensal bacteria, traditional and opportunistic pathogens, dysbiosis and bacterial killing in inflammatory bowel diseases. Curr Opin Infect Dis 22 : 292301.[PubMed] [CrossRef]
20. Barrett JC,, Hansoul S,, Nicolae DL,, Cho JH,, Duerr RH,, Rioux JD,, Brant SR,, Silverberg MS,, Taylor KD,, Barmada MM,, Bitton A,, Dassopoulos T,, Datta LW,, Green T,, Griffiths AM,, Kistner EO,, Murtha MT,, Regueiro MD,, Rotter JI,, Schumm LP,, Steinhart AH,, Targan SR,, Xavier RJ,, Libioulle C,, Sandor C,, Lathrop M,, Belaiche J,, Dewit O,, Gut I,, Heath S,, Laukens D,, Mni M,, Rutgeerts P,, Van Gossum A,, Zelenika D,, Franchimont D,, Hugot JP,, de Vos M,, Vermeire S,, Louis E,, Cardon LR,, Anderson CA,, Drummond H,, Nimmo E,, Ahmad T,, Prescott NJ,, Onnie CM,, Fisher SA,, Marchini J,, Ghori J,, Bumpstead S,, Gwilliam R,, Tremelling M,, Deloukas P,, Mansfield J,, Jewell D,, Satsangi J,, Mathew CG,, Parkes M,, Georges M,, Daly MJ . 2008. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn’s disease. Nat Genet 40 : 955962.[PubMed] [CrossRef]
21. Larsen N,, Vogensen FK,, Gobel R,, Michaelsen KF,, Abu Al-Soud W,, Sorensen SJ,, Hansen LH,, Jakobsen M . 2011. Predominant genera of fecal microbiota in children with atopic dermatitis are not altered by intake of probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium animalis subsp. lactis Bi-07. FEMS Microbiol Ecol 75 : 482496.[PubMed] [CrossRef]
22. Garcia-Mazcorro JF,, Lanerie DJ,, Dowd SE,, Paddock CG,, Grutzner N,, Steiner JM,, Ivanek R,, Suchodolski JS . 2011. Effect of a multi-species synbiotic formulation on fecal bacterial microbiota of healthy cats and dogs as evaluated by pyrosequencing. FEMS Microbiol Ecol 78 : 542554.[PubMed] [CrossRef]
23. McNulty NP,, Yatsunenko T,, Hsiao A,, Faith JJ,, Muegge BD,, Goodman AL,, Henrissat B,, Oozeer R,, Cools-Portier S,, Gobert G,, Chervaux C,, Knights D,, Lozupone CA,, Knight R,, Duncan AE,, Bain JR,, Muehlbauer MJ,, Newgard CB,, Heath AC,, Gordon JI . 2011. The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins. Sci Transl Med 3 : 106ra106. [PubMed] [CrossRef]
24. Sellon RK,, Tonkonogy S,, Schultz M,, Dieleman LA,, Grenther W,, Balish E,, Rennick DM,, Sartor RB . 1998. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun 66 : 52245231.[PubMed]
25. Imaoka A,, Matsumoto S,, Setoyama H,, Okada Y,, Umesaki Y . 1996. Proliferative recruitment of intestinal intraepithelial lymphocytes after microbial colonization of germ-free mice. Eur J Immunol 26 : 945948.[PubMed] [CrossRef]
26. Bauer E,, Williams BA,, Smidt H,, Verstegen MW,, Mosenthin R . 2006. Influence of the gastrointestinal microbiota on development of the immune system in young animals. Curr Issues Intest Microbiol 7 : 3551.[PubMed]
27. Bansal T,, Alaniz RC,, Wood TK,, Jayaraman A . 2010. The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation. Proc Natl Acad Sci USA 107 : 228233.[PubMed] [CrossRef]
28. Shahinas D,, Silverman M,, Sittler T,, Chiu C,, Kim P,, Allen-Vercoe E,, Weese S,, Wong A,, Low DE,, Pillai DR . 2012. Toward an understanding of changes in diversity associated with fecal microbiome transplantation based on 16S rRNA gene deep sequencing. MBio 3 : e00338-12. doi:10.1128/mBio.00338-12. [CrossRef]
29. Suchodolski JS,, Dowd SE,, Westermarck E,, Steiner JM,, Wolcott RD,, Spillmann T,, Harmoinen JA . 2009. The effect of the macrolide antibiotic tylosin on microbial diversity in the canine small intestine as demonstrated by massive parallel 16S rRNA gene sequencing. BMC Microbiol 9 : 210. [PubMed] [CrossRef]
30. Dethlefsen L,, Huse S,, Sogin ML,, Relman DA . 2008. The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing. PloS Biol 6 : e280. doi:10.1371/journal.pbio.0060280. [PubMed] [CrossRef]
31. Syer SD,, Wallace JL . 2014. Environmental and NSAID-enteropathy: dysbiosis as a common factor. Curr Gastroenterol Rep 16 : 377. [PubMed] [CrossRef]
32. US Food and Drug Administration . 2011. Medical Foods. Guidance for industry: frequently asked questions about medical foods. http://www.fda.gov/Food/GuidanceComplianceRegulatoryInformation/GuidanceDocuments/MedicalFoods/ucm054048htm.
33. Prakash S,, Rodes L,, Coussa-Charley M,, Tomaro-Duchesneau C . 2011. Gut microbiota: next frontier in understanding human health and development of biotherapeutics. Biologics 5 : 7186.[PubMed] [CrossRef]
34. Rossi G,, Pengo G,, Caldin M,, Palumbo Piccionello A,, Steiner JM,, Cohen ND,, Jergens AE,, Suchodolski JS . 2014. Comparison of microbiological, histological, and immunomodulatory parameters in response to treatment with either combination therapy with prednisone and metronidazole or probiotic VSL#3 strains in dogs with idiopathic inflammatory bowel disease. Plos One 9 : e94699. doi:10.1371/journal.pone.0094699. [CrossRef]
35. Soo I,, Madsen KL,, Tejpar Q,, Sydora BC,, Sherbaniuk R,, Cinque B,, Di Marzio L,, Cifone MG,, Desimone C,, Fedorak RN . 2008. VSL#3 probiotic upregulates intestinal mucosal alkaline sphingomyelinase and reduces inflammation. Can J Gastroenterol 22 : 237242.[PubMed] [CrossRef]
36. Mardini HE,, Grigorian AY . 2014. Probiotic mix VSL#3 is effective adjunctive therapy for mild to moderately active ulcerative colitis: a meta-analysis. Inflamm Bowel Dis 20 : 15621567.[PubMed] [CrossRef]
37. Collado MC,, Meriluoto J,, Salminen S . 2007. Role of commercial probiotic strains against human pathogen adhesion to intestinal mucus. Lett Appl Microbiol 45 : 454460.[PubMed] [CrossRef]
38. Collado MC,, Grzeskowiak L,, Salminen S . 2007. Probiotic strains and their combination inhibit in vitro adhesion of pathogens to pig intestinal mucosa. Curr Microbiol 55 : 260265.[PubMed] [CrossRef]
39. Lee YK,, Puong KY,, Ouwehand AC,, Salminen S . 2003. Displacement of bacterial pathogens from mucus and Caco-2 cell surface by lactobacilli. J Med Microbiol 52 : 925930.[PubMed] [CrossRef]
40. Jones SE,, Versalovic J . 2009. Probiotic Lactobacillus reuteri biofilms produce antimicrobial and anti-inflammatory factors. BMC Microbiol 9 : 35. [PubMed] [CrossRef]
41. Fukuda S,, Toh H,, Taylor TD,, Ohno H,, Hattori M . 2012. Acetate-producing bifidobacteria protect the host from enteropathogenic infection via carbohydrate transporters. Gut Microbes 3 : 449454.[PubMed] [CrossRef]
42. Lin PW,, Myers LE,, Ray L,, Song SC,, Nasr TR,, Berardinelli AJ,, Kundu K,, Murthy N,, Hansen JM,, Neish AS . 2009. Lactobacillus rhamnosus blocks inflammatory signaling in vivo via reactive oxygen species generation. Free Radic Biol Med 47 : 12051211.[PubMed] [CrossRef]
43. Lammers KM,, Brigidi P,, Vitali B,, Gionchetti P,, Rizzello F,, Caramelli E,, Matteuzzi D,, Campieri M . 2003. Immunomodulatory effects of probiotic bacteria DNA: IL-1 and IL-10 response in human peripheral blood mononuclear cells. FEMS Immunol Med Microbiol 38 : 165172.[PubMed] [CrossRef]
44. Shen TY,, Qin HL,, Gao ZG,, Fan XB,, Hang XM,, Jiang YQ . 2006. Influences of enteral nutrition combined with probiotics on gut microflora and barrier function of rats with abdominal infection. World J Gastroenterol 12 : 43524358.[PubMed] [CrossRef]
45. Simeoli R,, Mattace Raso G,, Lama A,, Pirozzi C,, Santoro A,, Di Guida F,, Sanges M,, Aksoy E,, Calignano A,, D’Arienzo A,, Meli R . 2015. Preventive and therapeutic effects of Lactobacillus paracasei B21060-based synbiotic treatment on gut inflammation and barrier integrity in colitic mice. J Nutr 145 : 12021210.[PubMed] [CrossRef]
46. Bayoumi MA,, Griffiths MW . 2012. In vitro inhibition of expression of virulence genes responsible for colonization and systemic spread of enteric pathogens using Bifidobacterium bifidum secreted molecules. Int J Food Microbiol 156 : 255263.[PubMed] [CrossRef]
47. Medellin-Pena MJ,, Wang H,, Johnson R,, Anand S,, Griffiths MW . 2007. Probiotics affect virulence-related gene expression in Escherichia coli O157:H7. Appl Environ Microbiol 73 : 42594267.[PubMed] [CrossRef]
48. Allaart JG,, van Asten AJ,, Vernooij JC,, Grone A . 2011. Effect of Lactobacillus fermentum on beta2 toxin production by Clostridium perfringens . Appl Environ Microbiol 77 : 44064411.[PubMed] [CrossRef]
49. Castagliuolo I,, Riegler MF,, Valenick L,, LaMont JT,, Pothoulakis C . 1999. Saccharomyces boulardii protease inhibits the effects of Clostridium difficile toxins A and B in human colonic mucosa. Infect Immun 67 : 302307.[PubMed]
50. Takeda K,, Kaisho T,, Akira S . 2003. Toll-like receptors. Annu Rev Immunol 21 : 335376.[PubMed] [CrossRef]
51. Schlee M,, Wehkamp J,, Altenhoefer A,, Oelschlaeger TA,, Stange EF,, Fellermann K . 2007. Induction of human beta-defensin 2 by the probiotic Escherichia coli Nissle 1917 is mediated through flagellin. Infect Immun 75 : 23992407.[PubMed] [CrossRef]
52. Granato D,, Bergonzelli GE,, Pridmore RD,, Marvin L,, Rouvet M,, Corthesy-Theulaz IE . 2004. Cell surface-associated elongation factor Tu mediates the attachment of Lactobacillus johnsonii NCC533 (La1) to human intestinal cells and mucins. Infect Immun 72 : 21602169.[PubMed] [CrossRef]
53. Matsuguchi T,, Takagi A,, Matsuzaki T,, Nagaoka M,, Ishikawa K,, Yokokura T,, Yoshikai Y . 2003. Lipoteichoic acids from Lactobacillus strains elicit strong tumor necrosis factor alpha-inducing activitives in macrophages through toll-like receptor 2. Clin Diagn Lab Immunol 10 : 259266.[PubMed]
54. Mack DR,, Ahrne S,, Hyde L,, Wei S,, Hollingsworth MA . 2003. Extracellular MUC3 mucin secretion follows adherence of Lactobacillus strains to intestinal epithelial cells in vitro . Gut 52 : 827833.[PubMed] [CrossRef]
55. Yan F,, Cao HW,, Cover TL,, Whitehead R,, Washington MK,, Polk DB . 2007. Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth. Gastroenterology 132 : 562575.[PubMed] [CrossRef]
56. Shima T,, Fukushima K,, Setoyama H,, Imaoka A,, Matsumoto S,, Hara T,, Suda K,, Umesaki Y . 2008. Differential effects of two probiotic strains with different bacteriological properties on intestinal gene expression, with special reference to indigenous bacteria. FEMS Immunol Med Microbiol 52 : 6977.[PubMed] [CrossRef]
57. Brisbin JT,, Zhou H,, Gong J,, Sabour P,, Akbari MR,, Haghighi HR,, Yu H,, Clarke A,, Sarson AJ,, Sharif S . 2008. Gene expression profiling of chicken lymphoid cells after treatment with Lactobacillus acidophilus cellular components. Dev Comp Immunol 32 : 563574.[PubMed] [CrossRef]
58. Panigrahi P,, Braileanu GT,, Chen H,, Stine OC . 2007. Probiotic bacteria change Escherichia coli-induced gene expression in cultured colonocytes: implications in intestinal pathophysiology. World J Gastroenterol 13 : 63706378.[PubMed] [CrossRef]
59. Sonnenburg JL,, Chen CT,, Gordon JI . 2006. Genomic and metabolic studies of the impact of probiotics on a model gut symbiont and host. PLoS Biol 4 : e413. doi:10.1371/journal.pbio.0040413. [PubMed] [CrossRef]
60. Walter J,, Heng NC,, Hammes WP,, Loach DM,, Tannock GW,, Hertel C . 2003. Identification of Lactobacillus reuteri genes specifically induced in the mouse gastrointestinal tract. Appl Environ Microbiol 69 : 20442051.[PubMed] [CrossRef]
61. Bron PA,, Grangette C,, Mercenier A,, de Vos WM,, Kleerebezem M . 2004. Identification of Lactobacillus plantarum genes that are induced in the gastrointestinal tract of mice. J Bacteriol 186 : 57215729.[PubMed] [CrossRef]
62. Denou E,, Berger B,, Barretto C,, Panoff JM,, Arigoni F,, Brussow H . 2007. Gene expression of commensal Lactobacillus johnsonii strain NCC533 during in vitro growth and in the murine gut. J Bacteriol 189 : 81098119.[PubMed] [CrossRef]
63. Gerard P,, Brezillon C,, Quere F,, Salmon A,, Rabot S . 2008. Characterization of cecal microbiota and response to an orally administered Lactobacillus probiotic strain in the broiler chicken. J Mol Microbiol Biotechnol 14 : 115122.[PubMed] [CrossRef]
64. Fuentes S,, Egert M,, Jimenez-Valera M,, Ramos-Cormenzana A,, Ruiz-Bravo A,, Smidt H,, Monteoliva-Sanchez M . 2008. Administration of Lactobacillus casei and Lactobacillus plantarum affects the diversity of murine intestinal lactobacilli, but not the overall bacterial community structure. Res Microbiol 159 : 237243.[PubMed] [CrossRef]
65. Mar JS,, Nagalingam NA,, Song Y,, Onizawa M,, Lee JW,, Lynch SV . 2014. Amelioration of DSS-induced murine colitis by VSL#3 supplementation is primarily associated with changes in ileal microbiota composition. Gut Microbes 5 : 494503.[PubMed] [CrossRef]
66. White RSR, G,, Atherly T,, Webb C,, Hill S,, Steiner JM,, Suchodolski JS,, Jergens AE . 2015. Effect of VSL#3 probiotic strains on the intestinal microbiota in canine inflammatory bowel disease. J Vet Intern Med 9 : 423483. doi:10.1111/jvim.12491. [CrossRef]
67. Mountzouris KC,, Tsirtsikos P,, Kalamara E,, Nitsch S,, Schatzmayr G,, Fegeros K . 2007. Evaluation of the efficacy of a probiotic containing Lactobacillus, Bifidobacterium, Enterococcus, and Pediococcus strains in promoting broiler performance and modulating cecal microflora composition and metabolic activities. Poult Sci 86 : 309317.[PubMed] [CrossRef]
68. Vahjen W,, Taras D,, Simon O . 2007. Effect of the probiotic Enterococcus faecium NCIMB10415 on cell numbers of total Enterococcus spp., E. faecium and E. faecalis in the intestine of piglets. Curr Issues Intest Microbiol 8 : 17.[PubMed]
69. Gardiner GE,, Casey PG,, Casey G,, Lynch PB,, Lawlor PG,, Hill C,, Fitzgerald GF,, Stanton C,, Ross RP . 2004. Relative ability of orally administered Lactobacillus murinus to predominate and persist in the porcine gastrointestinal tract. Appl Environ Microbiol 70 : 18951906.[PubMed] [CrossRef]
70. Casey PG,, Gardiner GE,, Casey G,, Bradshaw B,, Lawlor PG,, Lynch PB,, Leonard FC,, Stanton C,, Ross RP,, Fitzgerald GF,, Hill C . 2007. A five-strain probiotic combination reduces pathogen shedding and alleviates disease signs in pigs challenged with Salmonella enterica serovar Typhimurium . Appl Environ Microbiol 73 : 18581863.[PubMed] [CrossRef]
71. Ohya T,, Marubashi T,, Ito H . 2000. Significance of fecal volatile fatty acids in shedding of Escherichia coli O157 from calves: experimental infection and preliminary use of a probiotic product. J Vet Med Sci 62 : 11511155.[PubMed] [CrossRef]
72. Stephens TP,, Loneragan GH,, Chichester LM,, Brashears MM . 2007. Prevalence and enumeration of Escherichia coli O157 in steers receiving various strains of Lactobacillus-based direct-fed microbials. J Food Prot 70 : 12521255.[PubMed]
73. Bhandari SK,, Xu B,, Nyachoti CM,, Giesting DW,, Krause DO . 2008. Evaluation of alternatives to antibiotics using an Escherichia coli K88+ model of piglet diarrhea: effects on gut microbial ecology. J Anim Sci 86 : 836847.[PubMed] [CrossRef]
74. Konstantinov SR,, Smidt H,, Akkermans AD,, Casini L,, Trevisi P,, Mazzoni M,, De Filippi S,, Bosi P,, de Vos WM . 2008. Feeding of Lactobacillus sobrius reduces Escherichia coli F4 levels in the gut and promotes growth of infected piglets. FEMS Microbiol Ecol 66 : 599607.[PubMed] [CrossRef]
75. Strompfova V,, Marcinakova M,, Simonova M,, Gancarcikova S,, Jonecova Z,, Scirankova L,, Koscova J,, Buleca V,, Cobanova K,, Laukova A . 2006. Enterococcus faecium EK13: an enterocin a-producing strain with probiotic character and its effect in piglets. Anaerobe 12 : 242248.[PubMed] [CrossRef]
76. Taras D,, Vahjen W,, Macha M,, Simon O . 2006. Performance, diarrhea incidence, and occurrence of Escherichia coli virulence genes during long-term administration of a probiotic Enterococcus faecium strain to sows and piglets. J Anim Sci 84 : 608617.[PubMed]
77. Yoshida Y,, Tsukahara T,, Ushida K . 2009. Oral administration of Lactobacillus plantarum Lq80 and Megasphaera elsdenii iNP-001 induces efficient recovery from mucosal atrophy in the small and the large intestines of weaning piglets. Anim Sci J 80 : 709715.[PubMed] [CrossRef]
78. Di Giancamillo A,, Vitari F,, Savoini G,, Bontempo V,, Bersani C,, Dell’Orto V,, Domeneghini C . 2008. Effects of orally administered probiotic Pediococcus acidilactici on the small and large intestine of weaning piglets. A qualitative and quantitative micro-anatomical study. Histol Histopathol 23 : 651664.[PubMed]
79. Borody TJ,, Paramsothy S,, Agrawal G . 2013. Fecal microbiota transplantation: indications, methods, evidence, and future directions. Curr Gastroenterol Rep 15 : 337. [PubMed] [CrossRef]
80. Kelly CR,, Kahn S,, Kashyap P,, Laine L,, Rubin D,, Atreja A,, Moore T,, Wu G . 2015. Update on fecal microbiota transplantation 2015: indications, methodologies, mechanisms, and outlook. Gastroenterology 149 : 223237.[PubMed] [CrossRef]
81. Brandt LJ,, Aroniadis OC . 2013. An overview of fecal microbiota transplantation: techniques, indications, and outcomes. Gastrointest Endosc 78 : 240249.[PubMed] [CrossRef]
82. Eiseman B,, Silen W,, Bascom GS,, Kauvar AJ . 1958. Fecal enema as an adjunct in the treatment of pseudomembranous enterocolitis. Surgery 44 : 854859.[PubMed]
83. Cammarota G,, Ianiro G,, Gasbarrini A . 2014. Fecal microbiota transplantation for the treatment of Clostridium difficile infection: a systematic review. J Clin Gastroenterol 48 : 693702.[PubMed] [CrossRef]
84. Brandt LJ,, Borody TJ,, Campbell J . 2011. Endoscopic fecal microbiota transplantation: “first-line” treatment for severe Clostridium difficile infection? J Clin Gastroenterol 45 : 655657.[PubMed] [CrossRef]
85. Anderson JL,, Edney RJ,, Whelan K . 2012. Systematic review: faecal microbiota transplantation in the management of inflammatory bowel disease. Aliment Pharmacol Ther 36 : 503516.[PubMed] [CrossRef]
86. Xu MQ,, Cao HL,, Wang WQ,, Wang S,, Cao XC,, Yan F,, Wang BM . 2015. Fecal microbiota transplantation broadening its application beyond intestinal disorders. World J Gastroenterol 21 : 102111.[PubMed] [CrossRef]
87. Smits LP,, Bouter KE,, de Vos WM,, Borody TJ,, Nieuwdorp M . 2013. Therapeutic potential of fecal microbiota transplantation. Gastroenterology 145 : 946953.[PubMed] [CrossRef]
88. Teixeira TF,, Collado MC,, Ferreira CL,, Bressan J,, Peluzio Mdo C . 2012. Potential mechanisms for the emerging link between obesity and increased intestinal permeability. Nutr Res 32 : 637647.[PubMed] [CrossRef]

Tables

Generic image for table
TABLE 1

Clinical disorders associated with altered intestinal microbiota

Citation: Suchodolski J, Jergens A. 2016. Recent Advances and Understanding of Using Probiotic-Based Interventions to Restore Homeostasis of the Microbiome for the Prevention/Therapy of Bacterial Diseases, p 823-841. In Kudva I, Cornick N, Plummer P, Zhang Q, Nicholson T, Bannantine J, Bellaire B (ed),

Virulence Mechanisms of Bacterial Pathogens, Fifth Edition

. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.VMBF-0025-2015
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TABLE 2

Practical considerations for FMT

Citation: Suchodolski J, Jergens A. 2016. Recent Advances and Understanding of Using Probiotic-Based Interventions to Restore Homeostasis of the Microbiome for the Prevention/Therapy of Bacterial Diseases, p 823-841. In Kudva I, Cornick N, Plummer P, Zhang Q, Nicholson T, Bannantine J, Bellaire B (ed),

Virulence Mechanisms of Bacterial Pathogens, Fifth Edition

. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.VMBF-0025-2015

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