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The Bacterial Spore: from Molecules to Systems

Editors: Adam Driks1, Patrick Eichenberger2
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Affiliations: 1: Stritch School of Medicine, Loyola University Chicago, Maywood, IL; 2: Center for Genomics & Systems Biology, New York University, New York, NY
Content Type: Monograph
Format: Electronic
Publication Year: 2016

Category: Bacterial Pathogenesis

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The study of bacterial spores spans biosecurity to ecology.

The first articles describing the sporulation process were published by Robert Koch and Ferdinand Cohn in the late 19th century. Although most of the work accomplished in the past 50 years has focused on the model organism , more recent work significantly expanded the scope of sporulation research to integrate medically relevant spore pathogens, such as and , as well as investigations of the ecology of spore-forming species. This new direction is supported by an explosion of novel techniques that can also be applied to nonmodel organisms, such as next-generation sequencing, metagenomics, and transcriptomics.

provides a comprehensive series of reviews of the major topics in spore biology that represent intensive, cutting-edge spore research. Editors Adam Driks and Patrick Eichenberger assembled chapters written by a team of diverse and multidisciplinary experts in biodefense and microbial forensics to produce an overview of topics of spore research, such as spore molecular biology, bioremediation, systems biology, issues in biodefense, and the challenge of food safety that is accessible to any reader, regardless of expertise. also encompasses the diversity of spore research, which will appeal to those seeking to broaden their knowledge.

is a reference for a wide range of readers, including geneticists, cell biologists, physiologists, structural and evolutionary biologists, applied scientists, advanced undergraduate and graduate students, and nonresearchers, such as national security professionals.

is an ambitious effort at consolidating this body of research in a way that highlights the biological diversity of bacterial spore formers, their industrial and medical applications, and fundamental mechanistic insights gained from their study in a way that is accessible to both the novice and expert microbiologist.”

Kumaran S. Ramamurthi, Ph.D., Investigator, National Cancer Institute, National Institutes of Health

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