1887

Chapter 4 : Getting a Handle on Cell Organization

MyBook is a cheap paperback edition of the original book and will be sold at uniform, low price.

Preview this chapter:
Zoom in
Zoomout

Getting a Handle on Cell Organization, Page 1 of 2

| /docserver/preview/fulltext/10.1128/9781555819606/9781555819590_Chap04-1.gif /docserver/preview/fulltext/10.1128/9781555819606/9781555819590_Chap04-2.gif

Abstract:

Structural organization is one of the most conspicuous features of cells, and possibly the most elusive. No one really doubts that cell functions commonly require that the right molecules be in the right place at the right time, or that spatial organization is what distinguishes a living cell from a soup of its molecular constituents. But the tradition that has dominated biological research for the past century mandates a focus on the molecules, and so our first step is commonly to grind the exquisite architecture of the living cell into a pulp. Few molecular scientists have asked whether anything irretrievable is lost by this brutal routine. Such questions as how molecules find their proper place in a framework of orders of greater magnitude, or how spatial order is transmitted from one generation to the next, have been largely neglected until recently.

Citation: Harold F. 2016. Getting a Handle on Cell Organization, p 11-15. In Schaechter M, In the Company of Microbes: 10 Years of Small Things Considered. ASM Press, Washington, DC. doi: 10.1128/9781555819606.ch4
Highlighted Text: Show | Hide
Loading full text...

Full text loading...

Figures

Image of Untitled
Untitled

Citation: Harold F. 2016. Getting a Handle on Cell Organization, p 11-15. In Schaechter M, In the Company of Microbes: 10 Years of Small Things Considered. ASM Press, Washington, DC. doi: 10.1128/9781555819606.ch4
Permissions and Reprints Request Permissions
Download as Powerpoint
Image of Untitled
Untitled

Frank Harold is an affiliate professor in the Department of Microbiology, University of Washington Health Sciences Center. Now retired, he remains engaged with science as a writer and unlicensed philosopher.

Citation: Harold F. 2016. Getting a Handle on Cell Organization, p 11-15. In Schaechter M, In the Company of Microbes: 10 Years of Small Things Considered. ASM Press, Washington, DC. doi: 10.1128/9781555819606.ch4
Permissions and Reprints Request Permissions
Download as Powerpoint

References

/content/book/10.1128/9781555819606.chap04
1. Harold FMMolecules into cells: specifying spatial architecture.Microbiol Mol Biol Rev.20056954464
2. Karsenti ESelf-organization in cell biology: a brief history.Nat Rev Mol Cell Biol.2008925562
3. Lartigue C, Glass JI, Alperovich N, Pieper R, Parmar PP, Hutchison CA3rd,, Smith HO, Venter JCGenome transplantation in bacteria: changing one species to another.Science.2007317632638
4. Liu AP, Fletcher DAOpinion: Biology under construction: in vitro reconstitution of cellular function.Nature Reviews Molecular Cell Biology2009September10644650
5. Martin SGMicrotubule-dependent cell morphogenesis in the fission yeast.Trends Cell Biol20099447454
6. Ramamurthi KS, Lecuyer S, Stone HA, Losick RGeometric cue for protein localization in a bacterium.Science2009613541357
7. Terenna CR, Makushok T, Velve-Casquillas G, Baigl D, Chen Y, Bornens M, Paoletti A, Piel M, Tran PTPhysical mechanisms redirecting cell polarity and cell shape in fission yeast.Curr Biol.20081817481753

This is a required field
Please enter a valid email address
Please check the format of the address you have entered.
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error