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Chapter 26 : Fecal Transplants in the “Good Old Days”

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Fecal Transplants in the “Good Old Days”, Page 1 of 2

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Abstract:

I had a conversation with some colleagues last week about “personalized medicine,” which has been transformed now into the term “precision medicine.” The conversation revolved around what to do about the perceived effects of antibiotic treatment on the microbiota of individuals. How does one treat a patient without disrupting his or her microbiota? Do we create new classes of antimicrobials that target only a precise pathogen? I opined that I thought the day was coming when all individuals might have the microbiota from each anatomic site preserved so that it could be reconstituted after some catastrophic disruption caused by antimicrobial therapy for an infection, transplantation, surgery etc. The topic of fecal transplantation and how successful it has been for the treatment of intractable infection then came up. Would fecal reconstitution really work?

Citation: Falkow S. 2016. Fecal Transplants in the “Good Old Days”, p 106-109. In Schaechter M, In the Company of Microbes: 10 Years of Small Things Considered. ASM Press, Washington, DC. doi: 10.1128/9781555819606.ch26
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Citation: Falkow S. 2016. Fecal Transplants in the “Good Old Days”, p 106-109. In Schaechter M, In the Company of Microbes: 10 Years of Small Things Considered. ASM Press, Washington, DC. doi: 10.1128/9781555819606.ch26
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Stanley Falkow is Robert W. and Vivian K. Cahill Professor in Cancer Research, Emeritus, and Professor Emeritus of Microbiology and Immunology, Stanford University School of Medicine. He is also a past president of the ASM, where he has been a member for 61 years.

Citation: Falkow S. 2016. Fecal Transplants in the “Good Old Days”, p 106-109. In Schaechter M, In the Company of Microbes: 10 Years of Small Things Considered. ASM Press, Washington, DC. doi: 10.1128/9781555819606.ch26
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